Process

Development

Rapidly scaled-up
bulk cGMP liquid media

www.safcbiosciences.com Member of the Sigma-Aldrich Group

QUICK SCALE™ liquid media
• cGMP liquid media rapidly scaled-up
• Consistent and reliable performance
• Focused on industrial process development customers

Process development groups in the biopharmaceutical

industry are under dynamic timelines which require flexibility
and responsiveness. When you do not have the time to wait
for bulk cGMP liquid media, we offer you QUICK SCALE™.

Bigger Better
• Catalog and custom media • cGMP production with cGMP
formulations available in media specifications
standardized 10 L, 20 L, 50 L,
• Single-use disposable bags, in
100 L and 200 L bag packaging
Polyethylene (PE) or Ethyl Vinyl
• 200 L to 2,000 L cGMP lot sizes Acetate (EVA) films
• Scaleable package options • Consistent and scaleable media
support small to large lot sizes packaging systems “on the shelf”
and ready to fill
• Rigging sets compatible with a
variety of applications

Features Specifications

Lot Size (Liters) 200 L - 2,000 L

Quality Status cGMP

Bag Sizes 10 L, 20 L, 50 L, 100 L and 200 L

Bag Films PE or EVA

Connectors 1⁄4” and 3/8” Male Quick Connect and weldable Size C16 C-Flex ®*

Sample/Supplementation Yes, spike or medicinal port

Additional Connectivity Yes, see table of additional rigging sets

cGMP Media Specifications Yes**

Documentation cGMP batch records

Validated Manufacturing Yes

* 1/4" for 10 L and 20 L bags and 3/8" for 50 L, 100 L and 200 L bags. Additional rigging sets are available
through BIOEAZE™. Please contact your Business Development Manager or Customer Service for details.
** Custom specifications require customer sign-off and approval prior to production.
SAFC Biosciences
10 L SAFCB PE Bag
Item #2288B

Faster
• Same lead times as 500 mL
and 1 L bottles
• Manufacturing/distribution sites in
SAFC Biosciences
10 L SAFCB EVA Bag both the US and Europe
Item #2720B
• Rapid sampling and
supplementation through spike port

QUICK SCALE™ lead times

10

Weeks

0
Media in standard QUICK SCALE™
or custom bags
Benefits
• Responsive solution: consistent
and scaleable
• Speed to market: reduce validation
time associated with switching bag
film and packaging size
• Convenience and connectivity with
weldable and quick connection fittings
• Time saved by filling bioreactors
with media from a single bulk bag
• QC testing records sooner to
provide data for specifications
• Saving time equals more time for
formulation/concentrate development
and optimization

Item No. Product Purpose

2720B 10 L Ethyl Vinyl Acetate (EVA) Bag Sterile 10 L EVA film bag

2721B 20 L Ethyl Vinyl Acetate (EVA) Bag Sterile 20 L EVA film bag

2286B 10 L Polyethylene (PE) Bag Sterile 10 L PE film bag

2287B 20 L Polyethylene (PE) Bag Sterile 20 L PE film bag

2321B 50 L Polyethylene (PE) Bag Sterile 50 L PE Film Bag

2320B 100 L Polyethylene (PE) Bag Sterile 100 L PE Film Bag

2319B 200 L Polyethylene (PE) Bag Sterile 200 L PE Film Bag

2675R Female Quick Connect to Fluid transfer for weldable application

Aseptic Connecting Device (ACD) Sterile

2674R Female Quick Connect to Male Versatile transfer set for Quick Connect
or Female Luer Lock Option Sterile to luer lock applications

2676R Female Quick Connect to Dual Quick Connects Sterile Single to Double Quick Connect

2677R Female Quick Connect to Dual Sanitary Fittings Sterile Transfer set with sanitary fitting options

2671R Dispensing Bell Tube Set Sterile Female Quick Connect to filling bell
for dispensing

2672R Female Quick Connect to Steam-in-Place fluid transfer set

Steam-Thru™ Connection Sterile

1336R BIOEAZE™ Rigging Set 1⁄4” with 1⁄4” fluid transfer set 10 ft. length
Male-Female Quick Connects Sterile

1337R BIOEAZE™ Rigging Set 3/8” with 3/8” fluid transfer set 10 ft. length
Male-Female Quick Connects Sterile

1520R BIOEAZE™ Rigging Set 3/8” with 3/8” fluid transfer set 10 ft. length
Male-Female Quick Connects Sterile

1654R BIOEAZE™ Dispensing Tube Set Sterile Bottle/flask fluid transfer or dispensing
applications
Responsive Expertise
SAFC Biosciences is the world’s leading supplier
of cell culture reagents to producers of marketed biological
products. We are committed to supplying high-quality
critical raw materials and specialized cell culture products
and services to the global healthcare industry.

By providing the broadest range of highly customized

products and services possible to cell culture-based
manufacturing companies we demonstrate our commitment
to being responsive experts.
Contact us

United States

SAFC Biosciences, Inc.

13804 W. 107th Street
Lenexa, Kansas 66215
USA

Tel: +1 913-469-5580
Toll Free - USA: 1 800-255-6032
Fax: +1 913-469-5584
E-mail: info-na@sial.com

Europe

SAFC Biosciences Ltd.

Smeaton Road, West Portway
Andover, Hampshire SP10 3LF
UNITED KINGDOM

Tel: +44 (0)1264-333311

Fax: +44 (0)1264-332412
E-mail: info-eu@sial.com

Asia Pacific

SAFC Biosciences Pty. Ltd.

18-20 Export Drive
Brooklyn, Victoria 3025
AUSTRALIA

Tel: +61 (0)3-9362-4500

Toll Free - AUS: 1 800-200-404
Fax: +61 (0)3-9315-1656
E-mail: info-ap@sial.com

BIOEAZE™ is a trademark
of SAFC Biosciences, Inc.

C-Flex® is a registered trademark of

Consolidated Polymer Technologies, Inc.

Steam-Thru™ is a trademark
of Colder Products Company.

© 2006 SAFC Biosciences, Inc.

Issued November 2006 G051

www.safcbiosciences.com Member of the Sigma-Aldrich Group