Genetics Questions 1, "A couple who are first cousins come to see you. They want to get married. There is a family history of mitochondrial disease in the family, What would be the risk of having a child affected with the disease? AL Less than 10% B. 10%-chance #C. No increased risk compared to a non consanguineous marriage | Db. More than a 25% chance risk VE, ‘Need a full family pedigree to determine 2/ For the following family tree of an autosomal disorder with a population carrier frequency of 10%, what is the chance of the daughter having an affected child? 3, Whieh is the mast likely genetic mistake that will affect protein production? “6A. Mis-sense 9B Nonsense Cc. ‘Transversion D. Splicing defect E. Trisomy4, How do you explain the following pedigree? a A. Polygenic B. Autosomal dominant C. Autosomal recessive - BD. Mitochondrial E. Xelinked ny |