Antibiotic Actions of Herbs

John K. Chen Ph.D., Pharm.D., O.M.D., L.Ac.

Antibiotic
Antibacterial Antiviral Antifungal Antiparasitic Antineoplastic

Clinical Presentation of Heat

Heat/fire Damp heat Heat in the blood Toxic heat Deficient heat

Heat and Fire

High fever, aversion to heat, thirst, restlessness, irritability, delirium

Damp Heat
Burning and pain during urination Fatigue, yellow skin and sclera

Heat in the Blood

Restlessness, irritability, delirium, semiconsciousness, purpura and bleeding

Toxic Heat
Febrile diseases, diarrhea, dysentery, abscesses of internal organs, surface pus, burns, wounds, soreness and swelling of the throat

Deficient Heat
Sensations of steaming bones, warmth in the palms and soles, night sweats, dry throat and mouth, irritability, insomnia

Clinical Presentation of Heat

Heat/Fire: high fever, aversion to heat, thirst, restlessness, irritability, delirium Damp heat: burning and pain during urination Heat in the blood: restlessness, irritability, delirium, semi-consciousness, purpura and bleeding Toxic heat: febrile diseases, diarrhea, dysentery, abscesses of internal organs, surface pus, burns, wounds, soreness and swelling of the throat Deficient heat: sensations of steaming bones, warmth in the palms and soles, night sweats, dry throat and mouth, irritability, insomnia

Herbs that Clear Heat

Heat-clearing herbs address imbalances caused by excessive heat, whether mild or extreme, at various levels of pathological penetration of the body, by clearing heat, purging fire, or cooling organs or substances injured by heat.

Anti-Bacterial Effect
Da Qing Ye (Folium Isatis seu Baphicacanthus) Ban Lan Gen (Radix Isatidis seu Baphicacanthi) Huang Lian (Rhizoma Coptidis) Huang Qin (Radix Scutellariae Baicalensis) Huang Bai (Cortex Phellodendri) Zhi Zi (Fructus Gardeniae Jasminoidis) *

Da Qing Ye & Ban Lan Gen

Da Qing Ye (Folium Isatis seu Baphicacanthus) - leaves Ban Lan Gen (Radix Isatidis seu Baphicacanthi) - root

Da Qing Ye & Ban Lan Gen

Antibiotic: broad-spectrum antibacterial, antiviral and antifungal effects. Antineoplastic: inhibiting effect against cancer cells in treating leukemia, sarcoma, and lung cancer Anti-inflammatory:

Da Qing Ye & Ban Lan Gen

Upper respiratory infection Measles and pneumonia Encephalitis B

Da Qing Ye & Ban Lan Gen

Sulfonylurea antidiabetics Sulfonamide antibiotics

Huang Lian (Rhizoma Coptidis)

Antibiotic: broad spectrum of antibacterial, antifungal and antiviral effects Anti-inflammatory: Antipyretic:

Huang Lian (Rhizoma Coptidis)

Bacterial dysentery Acute gastroenteritis or enteritis Pulmonary tuberculosis Suppurative otitis media

Berberine

Huang Lian & Berberine

Huang Lian Single herb More effective Less resistance Systemic absorption Systemic infection Long half-life Berberine Single compound Less effective More resistance Poorly absorbed G.I. Infection only Short half-life

Huang Lian (Rhizoma Coptidis)

Prevents and treats cyclophosphamide urotoxicity (edema and bleeding) Allergenic (skin and anaphylactic reactions)

Huang Qin (Radix Scutellariae Baicalensis)

Antibiotic: Baicalin has a wide-spectrum of inhibitory effect Anti-inflammatory: Antipyretic: Antihypertensive:

Baicalin

Baicalin
Herb-Drug Interaction (Synergy) Beta-lactam-resistant Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). Baicalin restored effectiveness of ampicillin, amoxicillin, methicillin and cefotaxime

Huang Qin (Radix Scutellariae Baicalensis)

Hepatitis Epidemic encephalitis Scarlet fever

Huang Bai (Cortex Phellodendri)

Antibiotic: Huang Bai has demonstrated moderate antibiotic and antiviral effect Antihypertensive:

Huang Bai (Cortex Phellodendri)

Chronic bacterial dysentery Chronic bronchitis

Zhi Zi (Fructus Gardeniae Jasminoidis)

Antibiotic: bactericidal and bacteriostatic Antihypertensive: Hepatoprotective:

Zhi Zi (Fructus Gardeniae Jasminoidis)

Musculoskeletal sprain and strain Coronary artery disorders

Anti-Viral Effect
Jin Yin Hua (Flos Lonicerae Japonicae) Lian Qiao (Fructus Forsythiae Suspensae) Chuan Xin Lian (Herba Andrographitis Paniculatae) *

Jin Yin Hua (Flos Lonicerae Japonicae)

Antibiotic: broad spectrum antibacterial and antiviral Anti-inflammatory and antipyretic

Jin Yin Hua (Flos Lonicerae Japonicae)

Common colds and influenza Prevention of upper respiratory tract infections

Lian Qiao (Fructus Forsythiae Suspensae)

Antibiotic: antibacterial and antiviral Anti-inflammatory:

Chuan Xin Lian (Herba Andrographitis Paniculatae)

Antibiotic: antibacterial and antiviral Antipyretic: Anti-inflammatory: Immunostimulant:

Chuan Xin Lian (Herba Andrographitis Paniculatae)

Nasosinusitis and rhinitis Upper respiratory tract infection

Anti-Neoplastic Effect
Ku Shen Zi (Semen Sophorae Flavescentis) Ban Zhi Lian (Herba Scutellaria Barbatae) Bai Hua She She Cao (Herba Hedyotidis Diffusae) *

Anti-Pyretic Effect
Shi Gao (Gypsum) Zhi Mu (Rhizoma Anemarrhenae Asphodeloidis)

Synergistic Anti-Pyretic Effect

Shi Gao: quick onset but short duration of action. Zhi Mu: slower onset but much longer duration of action.

Time

Anti-Hypertensive Effect
Zhi Zi (Fructus Gardeniae Jasminoidis) Long Dan Cao (Radix Gentianae Scabra) Ye Ju Hua (Flos Chrysanthemi Indici) Xia Ku Cao (Spica Prunellae Vulgaris) *

Hepatoprotective Effect

Huang Qin (Radix Scutellariae Baicalensis) Zhi Zi (Fructus Gardeniae Jasminoidis) Long Dan Cao (Radix Gentianae Scabra) Yin Chen Hao (Herba Artemisiae Capillaris) *

Antibiotic Formulas (Localized)

Yin Qiao San (Honeysuckle and Forsythia Powder) Qing Fei Tang (Clear the Lung Decoction) Qing Qi Hua Tan Wan (Clear the Qi and Transform Phlegm Pill) Yu N Jian (Jade Woman Decoction) Bai Tou Weng Tang (Pulsatilla Decoction) Ba Zheng San (Eight-Herb Powder for Rectification)

Antibiotic Formulas (Systemic)

Long Dan Xie Gan Tang (Gentiana Longdancao Decoction to Drain the Liver) Huang Lian Jie Du Tang (Coptis Decoction to Relieve Toxicity) Pu Ji Xiao Du Yin (Universal Benefit Decoction to Eliminate Toxin)

Antipyretic Formulas
Bai Hu Tang (White Tiger Decoction) Ma Xing Gan Shi Tang (Ephedra, Apricot Kernel, Licorice, and Gypsum Decoction) Sang Ju Yin (Mulberry Leaf and Chrysanthemum Decoction)

Herbal ABX
Baphicacanthus Leave (Da Qing Ye) Dandelion (Pu Gong Ying) Bidens (Xian Feng Cao) Pteris (Feng Wei Cao) Physalis Angulata (Pao Zai Cao)

Coptis (Huang Lian) Justicia (Shu Wei Huang) Lippia (Ya She Huang) Solidago (Liu Zhi Huang) Leucas (Hu Yao Huang) Stellaria (Cha Chi Huang)