VET. PHYSIO.

52 1st One-Hour Examination NAME: SCORE:

________ 1. What is an approximate value for hemoglobin concentration in a normal healthy dog? a. 5 g/dl b. 20 g/dl c. 15 g/dl d. 10 g/dl ________ 2. An erythrocyte just entering the blood stream and having a net-like appearance because of polyribosomes and ribosomes is known as a/an: a. reticulocyte c. polychromatophilic rubricyte b. rubriblast d. eosinophil ________ 3. Where is erythropoitin produced? a. bone marrow b. lungs c. spleen d. kidneys ________ 4. What is the name of the transport form of iron? a. hemosiderin b. transferrin c. ferritin d. granolla ________ 5. Which WBC is most numerous in pigs, cows, sheep, and goats? a. eosinophil b. neutrophil c. lymphocyte d. basophil ________ 6. What substance is formed during the coagulation process that converts fibrinogen to fibrin? a. thromboxane A2 c. thrombin b. thromboplastin d. prothrombin ________ 7. Which of the following best describes plasma? a. about 40% of blood composition contains no protein b. the cellular part of blood, about 40% of blood composition c. about 60% of blood composition contains fibrinogen d. about 60% of blood composition clot removed ________ 8. The PCV of a hematocrit determination refers to the: a. white cells and thrombocyte layer between the erythrocyte mass and plasma b. the erythrocyte mass at the bottom c. the yellowish liquid layer at the top of the hematocrit d. the total length of the hematocrit tube content ________ 9. Which of the following most accurately approximates the amount of blood in an animal? a. 2 percent of body weight c. 8 percent of body weight b. 16 percent of body weight d. 24 percent of body weight ________ 10. Erythropoiesis refers to: a. blood coagulation c. the disintegration scheme for b. the recycling of iron RBCs d. RBC production ________ 11. Which one of the following time periods would approximate the life span of erythrocytes in most domestic mammals? a. 100 hours b. 60 days c. 100 days d. 35 seconds ________ 12. Which one of the following best describes the hemoglogin molecule of blood? a. has ferric iron (Fe3+ ), combines with 1 molecule of oxygen b. has 1 heme group and 1 globin molecule c. has ferrous (Fe2+ ), combines with 4 molecules of oxygen d. has ferrous iron (Fe2+) when unoxygenated and ferric iron (Fe3+ ) when oxygenated ________ 13. When erythrocyte is disintegrated, the hemoglobin disintegrates and is incorporated into new RBCs. a. true b. false ________ 14. A yellowish color of plasma which may be coupled with a red color of urine is caused by: a. hemoglobin b. bilirubin c. iron d. bilinogen ________ 15. The basophil is the most numerous leukocyte in all of the domestic species a. true b. false ________ 16. Which leukocyte will become a macrophage when it enters tissue spaces or becomes attached certain blood channels? a. neutrophil b. basophil c. eosinophil d. monocyte ________ 17. A term which refers to a reduced number of erythrocyte is: a. anemia c. leukocytosis b. leukopenia d. polycythemia ________ 18. Which of the following cells assists in the immune response a. basophil c. erythrocyte b. platelet d. lymphocyte ________ 19. The mesh of the blood clot is: a. thrombin b. fibrin c. fibrinogen d. prothrombin ________ 20. Which one of the following represents the number of erythrocytes for most domestic species?

a. 7,000,000 b. 7,000,000/microliter of blood (mm3) c. 7,000,000/milliliter of blood\ d. 7,000,000/pound of body weight ________ 21. Arterial blood changes from a bright red color to a darker purplish color when it becomes venous blood. Which one of the following causes this? a. loss of oxygen b. gain of carbon dioxide ________ 22. A normal value for arterial blood pH would be closest to which of the following values? a. 3.8 b. 6.5 c. 7.4 d. 8.2 ________ 23. A differential WBC count and a total WBC count have been determined. Sixty of the 100 WBCs counted in the differential were determined to be neutrophils. The total WBC count (per standard unit) was 10,000. What is the absolute number of neutrophils? a. 6,000/standard unit c. 60 percent b. 10,000/standard until d. 60/standard unit ________ 24. Someone tells you that the hemoglobin concentration in a baby pig is 4 gm/dl. What would you say is the status of that pig? a. normal b. anemic c. leukopenic d. polycythemic ________ 25. Which of the following leukocytes has as their function to provide immunity to antigens (foreign substances)? a. monocytes c. lymphocytes b. eosinophils d. basophils e. neutrophils ________ 26. Which of the following cations plays an important role in blood coagulation? a. Na+ b. Mg2+ c. K+ d. Ca2+ ________ 27. Which one of the following substances provides for the breakdown of fibrin to fibrin degradation products? a. plasmin b. thromboxane A2 c. fibrinogen d. EDTA ________ 28. The blood volume of a 25 kg dog is 2000 ml, of which the plasma volume is 1200 ml. What is the PCV of this dog? a. 8% b. 60% c. 40% d. Towser ________ 29. What is the stimulus for the production of erythropoietin? a. tissue need for oxygen c. no stimulus, but constantly produced b. iron deficiency d. sympathetic division of ANS ________ 30. Which body organ is the site whereby insoluble bilirubin that is released from MPS cells is made soluble before its transport to the intestine? a. kidney c. bone marrow b. liver d. spleen ________ 31. Which one of the blood coagulation mechanisms is activated when blood escapes from the vessels into the surrounding tissues? a. extrinsic b. intrinsic c. the curdler ________ 32. Nearly all of the clotting factors are: a. carbohydrates b. proteins c. lipids d. minerals ________ 33. Nearly all of the clotting factors are produced in the: a. kidney b. lung c. liver d. intestinal epithelium ________ 34. Loss of individual integrity, fusion of lipoprotein membranes, and exposure of receptors for coagulation factors is characteristic for: a. Platelet adhesion c. platelet release reaction b. platelet activation d. platelet aggregation ________ 35. Tissue plasminogen activator (t-PA) is associated with: a. heparin production b. initiation of the intrinsic mechanism of blood coagulation c. erythrocyte production d. fibrin degradation II. ESSAY
1.

A dog weighs 10 kg, has a PCV of 42%, and a plasma volume of 500 ml. What is its blood volume expressed as percent of body weight.

2. Why is venous blood more acidic than arterial blood?

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