Code No: R050212306 Set No.

1
II B.Tech I Semester Regular Examinations, November 2007
TRANSPORT PHENOMENA IN BIOPROCESS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
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1. (a) What are the different parameters effecting the convective mass transport.
(b) Explain the mass transfer process .
(c) Define interfacial area. [8+6+2]

2. (a) Mention the different phases between which the mass transfer takes place.
(b) Write the equation to determine the liquid mass transfer flux.
(c) Write the equation to determine the mass transfer flux through gas film.
(d) Write the units of concentration. [4+5+5+2]

3. In an aerobic fermentation process, the typical average bubble diameter is 3 mm,

with an average raise velocity of 18 cm/s. If the diffusivity coefficient is 8 ×10−10 m2 /s.
Find the mass transfer coefficient on the basis of penetration theory. [16]

4. (a) Define power number and explain each term .

(b) Define impeller Reynolds number and explain each term .
(c) Define Froude number. What is its significance. [6+5+5]

5. (a) What are impellers, why are they used. Mention some important type of
impellers with figures.
(b) Sketch the following baffle arrangements [8+8]
i. Baffle set away from wall and at an angle for high viscosity liquids
ii. Baffles attached to the wall for low viscosity liquids.

6. Explain the role of shear in stirred fermenters . [16]

7. A hot flue gas at 800 C is flowing through a composite spherical shell formed by two
spheres having inner, middle and the outer radius as 10cm , 15cm, and 20cm.
Thermal conductivity of inner shell = 38 w/m0 C
Thermal conductivity of outer shell = 45 w/m0 C
Film coefficient of heat transfer at the outer surface of composite spherical shell is
10w/m2 0 C. Ambient air temperature is 280 C.
Calculate the rate of heat flow through the wall of composite spherical shell and
the temperature at the inner surface, at the interface and at the outer surface. [16]

8. (a) Write a general form of correlation to predict heat transfer coefficient .

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Code No: R050212306 Set No. 1
(b) Write equations for dimensionless numbers in the above equation.
(c) What is the significance of Nusselt number, Reynolds number, Prandtl number
and Grashof mumber. [4+4+8]

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Code No: R050212306 Set No. 2
II B.Tech I Semester Regular Examinations, November 2007
TRANSPORT PHENOMENA IN BIOPROCESS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. (a) Define a transfer process

(b) What is the transport property for momentum transfer, write the units.
(c) What is the transport property for energy transfer, write the units. How does
it vary with temperature. [4+4+8]

2. Write the expression to calculate maximum cell concentration. Define each term in
the above equation and write the units. [16]

3. Write the equation to calculate the mass transfer coefficient for mould pellets and
suspensions. Define the dimensionless numbers and write the units of each term
appearing in the above equation. [16]

4. Discuss the parameters on which the mixing power for non aerated fluids depend.
[16]

5. (a) Write the dimensions of dynamic viscosity.

(b) Write the SI units of viscosity.
(c) Define drag force.
(d) Define wall turbulence and free turbulence . [4+4+4+4]

6. Discuss the rheological parameters of the following cultures

(a) Endomuces sp
(b) Aureobasidium pullulans
(c) Penicillium chrysogenum
(d) Xanthomonas campestris [4+4+4+4]

7. Derive an equation for steady state heat flow through a flat wall of three layers.
The layers are in perfect thermal contact. [16]

8. A liquid stream is cooled from 700 C to 320 C in a double pipe heat exchanger. Fluid
flowing counter currently with this stream is heated from 20 0 C to 440 C. Calcu-
late the log mean temperature difference and the arithmetic mean temperature
difference. [16]

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Code No: R050212306 Set No. 3
II B.Tech I Semester Regular Examinations, November 2007
TRANSPORT PHENOMENA IN BIOPROCESS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. Explain the process of diffusion in bio processing. [16]

2. What are the various factors affecting oxygen mass transfer rate in fermentation
broths. [16]

3. How are the agitators used to improve the mass transfer rate are classified. What
type of agitators are used for better gas liquid contact, viscous liquids and slurries,
semi solid masses. [16]

4. Discuss the significance of impeller Reynold’s number and power number of gassed
and un gassed Newtonian fluids. [16]

5. (a) What is a stream line and a stream line flow.

(b) Sketch the stream lines for a constant fluid velocity and for a steady flow over
a submerged object. [8+8]

6. Describe the importance of mixing in bio processing. [16]

7. (a) Draw the temperature profile for heat transfer between fluids separated by a
solid wall.
(b) Explain the formation of thermal boundary layer. [6+10]

8. A stirred fermenter of diameter 4m contains a jacket for heat transfer. The fer-
menter is mixed using and impeller of diameter of one meter and operated at
50rpm. The physical properties of the broth are viscosity is 4 ×10−3 PaS; density
is 900kg/m3 ; heat capacity is 4.18KJ/kg 0 C; thermal conductivity is 0.67 w/m0 C.
Calculate the heat transfer coefficient. [16]

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Code No: R050212306 Set No. 4
II B.Tech I Semester Regular Examinations, November 2007
TRANSPORT PHENOMENA IN BIOPROCESS
(Bio-Technology)
Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
⋆⋆⋆⋆⋆

1. (a) Define a transfer process

(b) What is the transport property for momentum transfer, write the units.
(c) What is the transport property for energy transfer, write the units. How does
it vary with temperature. [4+4+8]
2. (a) Mention the different phases between which the mass transfer takes place.
(b) Write the equation to determine the liquid mass transfer flux.
(c) Write the equation to determine the mass transfer flux through gas film.
(d) Write the units of concentration. [4+5+5+2]
3. Write the equation to calculate the mass transfer coefficient for mould pellets and
suspensions. Define the dimensionless numbers and write the units of each term
appearing in the above equation. [16]
4. Write briefly on power requirement for mixing. [16]
5. (a) What are the factors to be considered while selecting an impeller for a partic-
ular operation.
(b) Sketch the impellers used for low to medium viscosity liquids.
(c) What are the important type of impellers used for mixing in agitated tanks.
(d) Draw the figure and explain the arrangement of baffles set away from the wall
for moderate viscosity liquids. [4+4+4+4]
6. Write briefly on mixing and the importance of mixing in bio processing. [16]
7. (a) What is conduction.
(b) State Fourier’s law of heat conduction.
(c) The front of a slab of lead (k = 35 w/m0 k) is kept at 1100 C and the back is
kept at 500 C. If the area of the slab is 0.4m2 and it is 0.03m thick, compute
the heat flux q, and the heat transfer rate, Q. [2+4+10]
8. (a) Give the Schematic representation of the double pipe heat exchanger.
(b) Draw the profile for temperature changes for counter current flow in a double
pipe heat exchanger.
(c) Draw the profile for temperature changes for co current flow in a double pipe
heat exchanger. [6+5+5]

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