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Unit 2: Science and the world of work Assignment Brief 1

Hextable School

Science department

Course Title: BTEC First Diploma in Applied Science

Tutor name:

Assignment
GlaxoSmithKline Case Study Ref:
Title:
Learner Name
Start Date: Deadline:

Unit 2: Science and the world of work

Scenario

Science technicians or assistant practitioners working in a laboratory need an understanding and an

awareness of how their role and how the section/department in which they work fits within the overall

company structure/organisation and how the role of the company fits within the scientific and local

community.

To complete this assignment, you need an understanding of the work environment for a variety of

science-based occupations. This will be done by carrying out a case study on the operations of

GlaxoSmithKline carried out at the company’s Dartford manufacturing facility.

You will need to research two pharmaceutical compounds using books, specialist medical publications

such as the Medical Index of Medical Specialities (MIMS) the British National Formulary (BNF) brochures or

web-sites.

During your study, you should collect as much information as you can about the organisation. You will

need to organise the information carefully to help you to show what you have found out.

Tutor Support Material/” Edexcel Level 2 BTEC First Certificate and Diploma in Applied Science – Issue 1 –
February 2006”
1
Assessment Evidence:
Unit Grading Criteria
The grading criteria that this assignment relates to:

P1: illustrate the aims, structure and functions of a science-based organisation or an


organisation that uses science.

U2 M1: describe how the different departments of the organization work with each other,
explain how the products or services contribute to society

D1: describe the advantages and disadvantages that the organization has for the lives
of people in the area and for the general public

P2: investigate and describe a scientific product or service supplied by the organization

M2: describe why the product or service is fit for purpose

D2: identify and compare a scientific product/service from a competing organisation

P3: identify and practically investigate a process used to make the identified product or
service supplied

M3: identify the scientific principles involved in making the product or service supplies

D3: explain the scientific principles involved in making the product or service supplied

Summary Assessors Feedback

Internal Verifiers Comment

Learners Signature

2 Tutor Support Material/” Edexcel Level 2 BTEC First


Certificate and Diploma in Applied Science – Issue 1 –
February 2006”
Unit 2: Science and the World of Work

GlaxoSmithKline Case Study


Task 1

1a.
• Illustrate the aims, structure and functions of GlaxoSmithKline (GSK).
• Is the organisation profit or non-profit making?
• Does the organisation provide a service or make a product?
• Use flow charts and diagrams to illustrate the structure of GSK.
• What are the functions of the different departments of GSK?
P1

1b.
• Describe how the different departments within GSK work together with each other
• Explain how the products provided by GSK contribute to society.
M1

1c.
• Describe the advantages and disadvantages that GSK has for the lives of people in the area
and for the general public.
 You should consider the effect on the local economy and of employment
opportunities.
 should consider the effect of the organisation on the local environment, such
as transport and road usage, air quality, water and waste management.
D1
Task 2

2a.
• Zidovudine is an anti-HIV compound produced by GSK for the treatment of patients suffering
from AIDS. Investigate and describe this product.
P2

2b.
• Zidovudine attacks HIV by preventing the work of an enzyme that is essential for the
replication of the virus
 Investigate the lifecycle of a virus
 Carry out research into the ‘mode of action’ of Zidovudine.
M2

2c.
• Zidovudine is known as a ‘reverse transcriptase inhibitor.’ The pharmaceutical company
Merck is a rival to GSK. Merck produces a compound called Crixivan. Crixivan is known as a
‘protease inhibitor.’ Compare the Zidovudine with Crixivan. You could compare
 Mode of action
 Structure of the compound
 Route of administration
 Cost
 Side effects
 Risks associated with taking each product
 Advice given to doctors on the administration of both compounds
D2

Task 3

This task requires you to carry out the synthesis of the pharmaceutical compound ‘Aspirin’. Aspirin is
not produced by GSK at Dartford; however, very similar processes are used by GSK to produce many
other types of compound. It is not possible to produce these compounds within the college as many of
the compounds are toxic or too expensive.

You should consult with your tutor at all stages of the practical activities. Your tutor will need to see
your plans before you begin. You will also need to select equipment and materials to be used and carry
out a risk assessment. You must record all your results from your practical work and show how you
used them to draw conclusions from the work.

3a.
• Identify one of the main scientific processes that are used to make Aspirin. Investigate this
process by manufacturing Aspirin in the laboratory. Provide evidence of practical work you
have carried out that demonstrates the selected process.
P3

3b.
• Use your practical work to help you to identify the scientific principles involved in making
Aspirin.
M3

3c.
• Use equations, formulas and diagrams, where appropriate, to explain the scientific principles
involved in making Aspirin.

D3

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