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Pharmacrystal NIPER JEE Question Notes

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FISCHER PROJECTN:2d(haworth:cyclic form).. Torsion angle0-30:SYN PERIPLANAR.Oto 30: SYN.O--30:-SYN.3090:SYN CLINAL.90-150:ANTICLINAL/GOUCHE/SKEW150180:ANTIPERIPLANAR(TRANS) SAW HORSE,NEUMANN,WEDGE:3d(eclipse) 1 rupee print: FINANCE MINISTER. Agarose gel:DNA. Orange book:list of drugs approvd by FDA. Red BOOK:Guidelines 4 toxicity. YELLOW BOOK:IPR. 3d QSAR:Molecular modeling Drug usd 4 chronic pain:METHADONE. SDS-PAGE: proteins identification 2010 us fda approval.. DALFAMPRIDINE:treat walking ability in people vd MULTIPLE SCLEROSIS..Moa:oral Potassium channl blocker. 2011 us fda.IOFLUPANE:radiop'ceutical indicatd 4 visualizatn of striatal dopamine transporter inpatients vd parkinsons disease.

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2011 US FDA VILAZODONE:Dual actng potent n SSRI and a 5HT1A receptor partial agonist.Treat MAJOR DEPRESSIVE DISORDER.Start prep. IgE: TYPE 1. IgA, IgG-TYPE 2 ( blood, thyroid ).

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ADENOSINE+DIPYRADAMOLE-POTENTIATION.as inhibit reuptake of adenosine by rbc. Drug 4 digitalis induced arythmia-PHENYTOIN,LIDOCAINE EPA-Environmental protectn act. OECD-Organisatn for Economic Cooperatn Development. EMEA-European Medicines for Evaluatn Agency CDSCO-Central Drug standards Control Organisatn. ICMR-Indian Council Of Medical Research, Welfare Ministry Health and Family

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GABAPENTIN ENACARBIL:Gabapentin is a prodrug..Treat:RESTLESS LEGS SYNDROME. VANDETANIB:kinase inhbtr..Treat THYROID CANCER. LINAGLIPTIN:dipeptidyl peptidase-4(DPP-4) Inhbtr..Improve glycemic cotrol in adults.. Treat TYPE 2 DIABETES MELITUS. ABIRATERONE ACETATE:Moa:CYP17 INHB..Usd in comb vd PREDNISONE 4 treating METASTATIC CASTRATION-RESISTANT PROSTATE CANCER BRACKETNG N MATRIXNG DESIGNS EVALUATN OF STABILITY DATA. Stability data package 4 REGISTRTN APPL IN CLIMATIC ZONES 3 AND 4

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Text on VALIDATN OF ANALYTICAL PROCEDURE IMPURITIES IN NEW DRUG SUB QUALITY OF BIOTEC PRDTS TEST PROCEDURE N ACEPTNCE stability test of NEW DRUG SUB N PRDTS PHOTOSTABILITY TESTNG of new drug sub n prdt Stability test 4 NEW DOSAGE FORMS ulman rxn: SYN OF DIPHENYL AMINE,DIPHENYL ETHERS,DIPHENYLS. wolfkishner red: SYN OF HIGH MOL WT Compounds wolf rearang: SYN OF KETENES. COELESEVELAM:more prefrd than other bile a' sesquesterant bcoz NO GIT DISTURBANCE..less costipatn bcoz holds more water as H-BOND present. ACE inhibtrs,diuretics should not be given vd NSAIDS(cox2 inhbtr) as decreases d activity.site of actn cox 1-ISOLEUCINE..COX 2-VALINE.. pencillin,cephalosporin,sulfonamide: cause HYPERSENSITIVITY RXN(ALLERGY)as contain NH2 grp.undergo GLUCURONIDE CONJUG generaly . disease genetherapy..SCID-Adenosine deaminase.

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HAEMOPHILIA B-factor9.SICKLE CEL ANEMIA-beta globin.DIABETES-GLUT 2,glucokinase. Coenzyme -TPP:Thiamine. FMN,FAD-Riboflavin. NAD+,NADP+:Niacin. COENZYM A(Co A)-Panthothenic acid quinine on oxd:QUINIC A'+MEROQUININE. Ketone body formatn:LIVER.

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