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  • Type 2 Treatment Algorithm

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    Octo Indradjaja
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    The IDF treatment algorithm for people with type 2 diabetes recommends lifestyle measures as the first line treatment. If HbA1c levels remain above 7%, metformin is considered as the first drug option, followed by sulfonylurea or alpha-glucosidase inhibitor as second-line options. If levels are still not at target, the algorithm suggests considering basal insulin, DPP-4 inhibitors, or thiazolidinediones as third-line treatment, and combining basal and meal-time insulin or intensifying to premix insulin as fourth-line options.

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    The IDF treatment algorithm for people with type 2 diabetes recommends lifestyle measures as the first line treatment. If HbA1c levels remain above 7%, metformin is considered as the first drug option, followed by sulfonylurea or alpha-glucosidase inhibitor as second-line options. If levels are still not at target, the algorithm suggests considering basal insulin, DPP-4 inhibitors, or thiazolidinediones as third-line treatment, and combining basal and meal-time insulin or intensifying to premix insulin as fourth-line options.

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    5 visualizzazioni1 pagina

    Type 2 Treatment Algorithm

    Caricato da

    Octo Indradjaja
    The IDF treatment algorithm for people with type 2 diabetes recommends lifestyle measures as the first line treatment. If HbA1c levels remain above 7%, metformin is considered as the first drug option, followed by sulfonylurea or alpha-glucosidase inhibitor as second-line options. If levels are still not at target, the algorithm suggests considering basal insulin, DPP-4 inhibitors, or thiazolidinediones as third-line treatment, and combining basal and meal-time insulin or intensifying to premix insulin as fourth-line options.

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    Attribution Non-Commercial (BY-NC)
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    IDF Treatment Algorithm for People with Type 2 Diabetes

    Lifestyle measures Then, at each step, if not to target (generally HbA1c 7.0 %) Consider first line
    Metformin Sulfonylurea or - Glucosidase inhibitor

    Consider second line


    Sulfonylurea Metformin (if not first line) or - Glucosidase inhibitor or DPP-4 inhibitor or Thiazolidinedione

    Consider third line


    Basal insulin or Pre-mix insulin or - Glucosidase inhibitor or DPP-4 inhibitor or Thiazolidinedione or GLP-1 agonist

    Consider fourth line


    Basal + meal-time insulin < Basal insulin, or Pre-mix insulin (later basal + meal-time) = usual approach = alternative approach

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