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  • Rheumatic Fever

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    Jeaneta Cheryl Patrick
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    Rheumatic fever is an autoimmune disease that can affect the heart, joints, and skin following a streptococcal throat infection. It is most common in children ages 5-15, peaking at age 8. Clinical manifestations include sore throat, fever, headache, rash, and inflammation of the heart (carditis), joints (arthritis), or involuntary movements (Sydenham's chorea). Diagnosis is based on having two major signs or one major sign and two minor signs associated with a prior streptococcal infection. Treatment involves eradicating the streptococcal infection with penicillin or erythromycin and using anti-inflammatory drugs. Prognosis depends on the extent of heart involvement, and prevention involves

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    Rheumatic fever is an autoimmune disease that can affect the heart, joints, and skin following a streptococcal throat infection. It is most common in children ages 5-15, peaking at age 8. Clinical manifestations include sore throat, fever, headache, rash, and inflammation of the heart (carditis), joints (arthritis), or involuntary movements (Sydenham's chorea). Diagnosis is based on having two major signs or one major sign and two minor signs associated with a prior streptococcal infection. Treatment involves eradicating the streptococcal infection with penicillin or erythromycin and using anti-inflammatory drugs. Prognosis depends on the extent of heart involvement, and prevention involves

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    Attribution Non-Commercial (BY-NC)
    Scarica in formato PPT, PDF, TXT o leggi online su Scribd
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    362 visualizzazioni15 pagine

    Rheumatic Fever

    Caricato da

    Jeaneta Cheryl Patrick
    Rheumatic fever is an autoimmune disease that can affect the heart, joints, and skin following a streptococcal throat infection. It is most common in children ages 5-15, peaking at age 8. Clinical manifestations include sore throat, fever, headache, rash, and inflammation of the heart (carditis), joints (arthritis), or involuntary movements (Sydenham's chorea). Diagnosis is based on having two major signs or one major sign and two minor signs associated with a prior streptococcal infection. Treatment involves eradicating the streptococcal infection with penicillin or erythromycin and using anti-inflammatory drugs. Prognosis depends on the extent of heart involvement, and prevention involves

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    di 15

    RHEUMATIC FEVER

    Prof. Dr.dr. Syarifuddin Rauf, SpA(K)

    OUTLINE
    DEFINITION
    INCIDENCE CLINICAL MANIFESTATION JONESS CRITERIA DIAGNOSIS

    TREATMENT,PROGNOSIS,PROPHYLACSIS

    RF : Autoimmune disease (heart, joint, skin


    Following throat infection : A group Hemolyticus streptococcus(ABHS)

    INCIDENCE: 5 -15 YEARS

    Top age : 8 years

    CLINICAL MANIFESTATION
    50% proceded by : Sore throat Headache Rash Fever

    Carditis :

    Myocarditis
    Endocarditis

    Pericarditis
    Murmur, abnormal electrocardiogram, echocardiogram Cardiomegali Heart failure

    Sydenhams Chorea :

    Involuntary movement
    15% of patients > Involuntary movements (hands, face, tongue speech incoherent) Weeks - months

    Subcutaneous nodules :
    Small bumps (< 1 cm) Over bony areas (knees) 3 10% Disappear in 1 2 weeks

    Erythema marginatum:

    Red rash
    Transient Trunk & extremities

    JONES CRITERIA
    Major manifestations Carditis
    Polyarthtitis Sydenham Chorea Erythema marginatum Subacute nodules

    Minor manifestations
    History of RF / RHD Polyarthalgia Fever

    Lab. Examination :
    BSR Leucocytosis

    CRP
    ECG : P-R interval

    MAJOR MANIFESTATION
    Arthritis : 70% of patients Joint pain & swelling

    Numerous joints involved


    Migratory polyarthritis

    DIAGNOSIS
    I. 2 MAJOR SIGNS II. 1 MAJOR SIGN + 2 MINOR SIGNS I or II should be associated with signs of INFECTION WITH A GROUP B HEMOLYTICUS STREPTOCOCCUS

    TREATMENT
    1. Eradication of ABHS : Penicillin, erythromycin
    2. Anti Rheumatic drugs :

    Mild RF (arthritis) : salycilates


    Moderate severe carditis : salicylates &

    steroids

    PROGNOSIS
    Extend of heart disease Poor : signs of carditis (Cardiomegali, heart

    failure)

    PREVENTION
    1. Primary prophylaxis : eradication of ABHS 2. Secondary prophylaxis : prevention of Rec. RF/RHD Penicillin : 0,6 1,2 million U/IM every 4 weeks (5 21 years)

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