UNIVERSI'TY Of JOlIDAN

Faculty OF Medicine

LECTURE NO: 15

,,------i[ DATE: 26/1 0/2008

,-.+------l DONE BY: MAJO KHAPER

'------I DR.: N ayf K aradsheh

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f'" ~ - ( C">
--,
-coo -CH1 -CH1 -C-COO
GOP g:re.,jLJ"- .
tt-KerogluUlate
~ co, -CO()-CH2-~CH2-C:JSCoA
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CQ}\SH ~ w~- tn> succinyl CoA PI CoASH
NAD"" Nl'DH ·H"'l- ... -, ....... succil'U.fe
d.-ketoglutarate 1hiGkinase _ t).1 kcal c... .._~,_;._
dehydrogenase

B //
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CH,2- 'C -COO'"
pyruva{e OM HS-CoA
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CcNsH ~~ <i CO,
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CH~-C~SCOA :_ _- :
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.<~"./ . .
N~O'" 11\IADh1 7- n1-
pYrUvate
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Act~1 CoA carMe
Synthase.
- 7· 7 K c ".f
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./~';-'

dehydrogenase

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C 1.0
-d'-o-
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CH
3 . ~ -r~} ~ d" ~I-) oAA HS-Co~
dfAytie. .-;» .~cetat; (p. "» , __d!. .._-+
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tfl<ltto/----;> Ii: oJ'" •
Cinllt
~
-
7/
CnASH ~::::;: , ~ CH,1-G ......0 SCoA ==~)
~TP AM P + PPj Acetyl CoA citta~ _1- 7 K c-l
~~ ~~...........-,~..,.
acetyl ccA synihlSI.
,
synthetase:
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........ q:\~~.!.'. 'Q.~9.?~'0.~~~\~ .. \':~'0?~ .
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AcetyL CoA
·.... ----aid-.,
. . . -. ------. / '- : F a:tty ~c :
: Amino acid : 4- Oxaloacetate Cilra{e -..-......,..... ~ : SYt:\thesis :
:__ ~~~~~~~i~ __: ( TCA \ ........•... -

cycle I .

lX-,/9futar.Ue 1'1>-:., .:~~.~~i~ "~.' _

.,
,- - - - -- . - -- . -- . - ~ - ~ ..& ~ -- --- Malate '~ : Amino acid :
: ~'~c.o~e~~~~:.s~: ; ~ \I

I
Succinyl CoA ~' N~urotransmIUe( I I
I (~rain) ii
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.-._.-.--_.--- I
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1 ... - - ....... · - .. - - - -

Heme
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synthesis
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.............................................................................................................................................

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.............................................................................................................................................

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.............................................................................................................................................

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