GNF

doenças sistemicas e rim

Exº
• Infecção
– GNF pós-infecciosas
– Dças víricas
• Inflamação
– Dças autoimunes
– Vasculites

Não é uma revisão exaustiva!

Primary Glomerular Diseases
Glomerular Diseases That Cause Nephrotic
Syndrome
Non-Immune Complex:

Minimal Change Disease

Focal Segmental Glomerulosclerosis

Collapsing Glomerulopathy
Tip Lesion Variant of FSGS
C1q Nephropathy
Primary Glomerular Diseases
Glomerular Diseases That Cause
Nephrotic Syndrome
Immune Complex

Membranous Glomerulonephritis

Membranoproliferative Glomerulonephritis

Dense Deposit Disease

Fibrillary Glomerulonephritis

Immunotactoid Glomerulopathy
 Glomerular Diseases That Cause
Hematuria Or Nephritic Syndrome

Postinfectious Glomerulonephritis

IgA Nephropathy/Henoch-Schönlein
Purpura
 Secondary Glomerular Diseases
Diseases Associated With Nephrotic Syndrome

Monoclonal Immunoglobulin Deposition Disease (MIDD):

Amyloid
Light Chain Deposition Disease

Other:
HIV Associated Nephropathy
Sickle Cell Nephropathy
Fabry Disease
Lecithin-Cholesterol Acyltransferase (LCAT) Deficiency
Type III Collagen Glomerulopathy (Collagenofibrotic
Glomerulopathy)
 Diseases Associated With Nephritic±Nephrotic
Syndrome or RPGN
Immune Mediated:
Mesangial Lupus Nephritis
Membranous Lupus Nephritis
Lupus Nephritis: Proliferative Forms (WHO III, IV)

Cryoglobulin-Related Glomerulonephritis

Anti-GBM Antibody-Mediated Glomerulonephritis

Non-immune Mediated:
Pauci-immune Necrotizing Crescentic
Glomerulonephritides: Wegener's
Granulomatosis/Microscopic Polyangiitis
 American Society of
Nephrology Annual Scientific
Meeting
October, 2000

Ronald Serologic Diagnosis of

J. Falk, Glomerular Disease
M.D.
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Source: Venkataseshan
VS et al, Medicine (Baltimore). 1990 Jul;69(4):200-1
Source: Venkataseshan
VS et al, Medicine (Baltimore). 1990 Jul;69(4):200-16.
Typical Hepatitis B - associated GN
biopsy: membranous and
membranoproliferative
 .
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Source: Venkataseshan
VS et al, Medicine (Baltimore). 1990 Jul;69(4):200-16.
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Source: Johnson RJ et al, Kidney Int. 1994 Dec;46(6
Typical appearance of MPGN with HCV on
renal biopsy
Treatment of HCV-associated severe MPGN and/or
vasculitis
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,
Pathology if HIVAN: Collapsing variant of
Focal pattern and microcysts in the renal tubules with
HIVAN
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A 27 year old patient with severe lupus
nephritis
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Source: Austin HA et al, Kidney Int. 1994 Fe

Prognostic factors
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Source: Hagen EC et al, Kidney Int. 1998 Mar;53(3):

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