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CHROMIUM COBALT SELENIUM MANGANESE MOLYBDENUM ZINC

Properties w/ B12 in Glutathione Widely distributed (second to


LIVER peroxidase-“active” iron)

P = 1 mg/ 100 20 mg esp in  LIVER, PANCREAS,


mL Mitochondria KIDNEY, BONE and MXs

Absorption Transmanganin – bound Fe2+/Ca2+/Cu2+


to B-Globulin - interfere in absorption
Function 1. FAT / CHO 1. RBC 1. Anti-oxidants 1. Coenzyme 1. Coenzyme 1. fat/CHO/CHON
metab. a. Glutamine synthase a. XO metabolism
2. normal fx’g 2. FR scavengers b. PYR carboxylase b. Aldehyde oxidase 2. Stabilize CHON, NA
2. Insulin of cells c. Mito SOD c. Sulfite oxidase 3. Integrity of subcell
3. acts w/ Vit. E organelles
3. “glucose a. Protect cell and 2. Form CT 2. Prosthetic group in 4. transport
tolerance factor” organelles from O2 enzymes that catalyze 5. immune function
 Cr complx 3. Growth and Reprod’cn REDOX 6. expression of genetic
b. unite H + O2 information
c. transfer ions 4. Fat/CHO metab
d. aid in Ig and 7. METALLOTHIONEIN
Uq synthesis - abundant
- detoxify metals
- inhibit thionein

8. stabilize DNA/RNA struc.


9. reqt: RNA POL
10. Replication/Transcription
- chromatin proteins
11. OB activity in BF

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