MEDICATION INFORMATION

GENERIC NAME TRADE NAMES Sevelamer Renagel NORMAL DOSAGE RANGE (ALSO INCLUDE ROUTE AND FREQUENCY) 800-1600mg per meal LAB VALUE ALTERATIONS CLASSIFICATION phosphate binders ONSET DURATION 5 days Unknown DRUG INTERACTIONS
May absorption of other drugs and effectiveness, especially drugs whose efficacy is dependent on tightly controlled blood levels absorption of ciprofloxacin

PEAK 2 Weeks

Monitor serum phosphorous, calcium, bicarbonate, and chloride levels periodically during therapy

MECHANISM OF ACTION (How does it work?)

A polymer that binds phosphate in the GI tract, preventing its absorption

Why is your patient getting this medication? Or What are some reasons that these medications are ordered?

Decreased serum phosphate levels and reduction in the consequences of hyperphosphatemia, in pt with Kidney failure

COMMON SIDE EFFECTS Diarrhea, dyspepsia, vomiting, constipation, flatulence, nausea.

NURSING IMPLICATIONS (What to focus on.) Doses of

concurrent medications, especially antiarrhythmics, should be spaced at least 1 hr before or 3 hr after sevelamer. Administer with meals. Do not break, chew, or crush tablets ; contents expand in water. Place contents of powder packet in a cup and mix thoroughly with at least 1 ounce of water for the 0.8 g dose or 2 ounces of water for the 2.4 g dose packet. Stir mixture vigorously (it does not dissolve) and drink entire preparation within 30 minutes or re-

TEACHING
Instruct patient to take sevelamer with meals as directed and to adhere to prescribed diet. Caution patient to space concurrent medications at least 1 hr before or 3 hr after sevelamer. Advise patient to notify health care professional if GI effects are severe or prolonged.

PREADMINISTRATION ASSESSMENT? GI Assessment

WHEN/WHY WOULD YOU HOLD? When ordered

WHAT WOULD YOU ASSESS POSTADMINISTRATION? Lab values, Monitor for GI issues.

suspend the preparation right before drinking.

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