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    Membrane protein biogenesis and trafficking - A typical cell - anatomical architecture and activity partition. Cells, organelles, molecules and signals. Membrane and spatial distribution of macromolecules. Three trafficking pathways: Gated transport Transmembrane transport vesicular transport.

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    Membrane protein biogenesis and trafficking - A typical cell - anatomical architecture and activity partition. Cells, organelles, molecules and signals. Membrane and spatial distribution of macromolecules. Three trafficking pathways: Gated transport Transmembrane transport vesicular transport.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Scarica in formato DOC, PDF, TXT o leggi online su Scribd
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    15 visualizzazioni1 pagina

    Outline and References

    Caricato da

    api-3700537
    Membrane protein biogenesis and trafficking - A typical cell - anatomical architecture and activity partition. Cells, organelles, molecules and signals. Membrane and spatial distribution of macromolecules. Three trafficking pathways: Gated transport Transmembrane transport vesicular transport.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Scarica in formato DOC, PDF, TXT o leggi online su Scribd
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    di 1

    Membrane protein biogenesis and trafficking

    Contact:

    Min Li, Ph.D.


    Johns Hopkins University School of Medicine
    733 North Broadway, BRB 319
    Baltimore, MD 21205

    410-614-5131
    minli@jhmi.edu
    www.molecularinteraction.org

    Outline:

    1. A typical cell – anatomical architecture and activity partition


    2. Cells, organelles, molecules and signals

    3. Membrane and spatial distribution of macromolecules

    4. Three trafficking pathways:

    • Gated transport
    • Transmembrane transport
    • Vesicular transport

    5. Defects in vesicular transport and human diseases

    Reviews:

    Mellman, I., and Warren, G. (2000). The road taken: past and
    future foundations of membrane traffic. Cell 100, 99-112.

    Bonifacino, J. S., and Glick, B. S. (2004). The mechanisms of


    vesicle budding and fusion. Cell 116, 153-166

    Discussion Paper:

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