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Solutions to Signal Transduction Research.

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Selleck has new recommendations for you based on your research area.
Recommended products related to MEK/Erk.

S1008

AZD6244(Selumetinib)

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Papers

AZD6244 is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm. S1531 BIX 02189 more

using Selleck products

1.Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation ------ Ramin Nazarian et al. Nature 16 December 2010 2.Vertical Targeting of the Phosphatidylinositol-3 Kinase Pathway as a Strategy for Treating Melanoma ------ Saadia A. Aziz, Lucia B. Jilaveanu, Christopher Zito, et al.Clin Cancer Res 2010;16:60296039.

BIX 02189 is a selective MEK5/ERK5 inhibitor with an IC50 of 59 nM. S1020 CI-1040 (PD184352) more

MEK 1/2 inhibitor. Ki of 300nM

Other Related Targets: MEK P38 MAPK B-Raf JNK Ras

Reviews
AZD6244 supplied by Selleck Chemicals. Produced Independently by Dr.Zhang, Tianjin Medical University.

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