Documenti di Didattica
Documenti di Professioni
Documenti di Cultura
www.pharmacygraduates.org
CONTENTS
INTRODUCTION ANATOMICAL DIFFERENCE BETWEEN BABY AND ADULT SKIN PHYSIOLOGICAL DIFFERENCE BETWEEN BABY AND ADULT SKIN BABY POWDERS FORMULATION EVALUATION BABY SHAMPOOS FORMULATION EVALUATION
www.pharmacygraduates.org
Need different skin and hair care Their exist anatomical and physiological differences The skin of the newborn is unripe.
www.pharmacygraduates.org
EPIDERMIS:
Only in prematures The stratum corneum is lacking, a significant barrier function , photoprotection, immunological barrier, and receptor function, respectivelystill has to develop progressively. The stratum germinativum , melanocytes are less pigmented, which explains the pale color of the newborns skin.
www.pharmacygraduates.org
In the dermis, numerous fibroblasts produce elastic and collagen fibers but fewer in number than in adult life. It is known that the dermal matrix differs in composition depending on age. Indeed, during development, the water, glycogen, and hyaluronic acid contents of the matrix decrease, but its dermatan sulfate content increases
www.pharmacygraduates.org
Dermal absorption in newborn skin is similar to that observed in adult skin. For babies, however, a number of typical risk factors exist.
The surface area/body weight ratio is 2.3-fold higher in newborns than in adults .
www.pharmacygraduates.org
BABY CARE PRODUCTS: Baby care products are defined as the paediatric cosmetics which usually contain harmless ingredients that make no or therapeutic value and is used more or less to prevent rather than cure undesirable skin problems. Different kinds of baby care products are baby creams, baby lotions, baby oils, baby powders, baby shampoos, etc..,.
www.pharmacygraduates.org
www.pharmacygraduates.org
Baby powders are used for the maintenance of Epidermal physiology and the skin care in the new borns.
Formulation:
Talc Magnesium stearate light calcium carbonate Perfume
www.pharmacygraduates.org
Shade
control and lighting: Pressure testing: Flow property Particle size determination
www.pharmacygraduates.org
www.pharmacygraduates.org
BABY SHAMPOOS
www.pharmacygraduates.org
Baby shampoos are used to clean the scalp and the hair of the babies
FORMULATION:
Surfactants 15-30% Foam Stabilizers 1-4 % Thickener 0-5% Deionized Water Q.S
www.pharmacygraduates.org
Preservatives 0,1-1 % Humectants 1-5 % PH Buffers Q.S. neutral pH Chelating Agents 0-0,02 % Pearlescing/ opacifying agents 0,2-2% Perfume 0,5-1 % Colouring agents Q.S. Conditioning agents Q.S. desired effect
www.pharmacygraduates.org
Evaluation of Safety
Skin
www.pharmacygraduates.org
www.pharmacygraduates.org
Apply product
Since shampoos are liquid or viscous preparations, they are liable to microbial growth. Hence the preservative is added to prevent the microbial growth. This test is usually done by a method called as Challenge study. According to this study, the product is said to be preserved when it does not support microbial growth even after repeated attacks of various micro-organisms.
www.pharmacygraduates.org
Intially app. Starin of micro organism is selceted and is considered as test organism Culture of test organism is prepared
The product is inoculted repeated in culture media and studies are Carried out for 10- 12 weeks Along with test ,control samples are prepared and reserved for reference Usaually two types of control samples are prepared i.e., one sample long with preservative and with out preservative The test comes to conclusion only when it has been proven that has not supportedMicrobial growth
www.pharmacygraduates.org
Baby skin is very sensitive than adult, so we should take a lot of care What ever we are applying should be Non toxic Non irritant Free from microbial contamination Totally it must be mild and Safer to use.
www.pharmacygraduates.org
Sharma PP. Cosmetics-formulation, manufacturing and quality control. 3rd ed., Vandana Publications Pvt. Ltd., Delhi, 2005. Nanda S, Nanda A, Khar RK. Cosmetic technology. Brila Publications Pvt. Ltd., Delhi, 2007. Amparo Salvador, Alberto Chisvert. Analysis of Cosmetics products. 1st ed., Elsevier Publications Pvt. Ltd., U.K, 2007. Andre O. Barel, Marc Paye, Howard I. Maibach. Hand book of Cosmetic Science and Technology. 3rd ed., Informa Healthcare USA, 2009.
www.pharmacygraduates.org
www.pharmacygraduates.org