Generic/ Classificatio Dosage Mode of Action Indication Contraindications Drug Interaction Nursing Considerations

Brand Name n / Cautions

Magnesium Mineral and Drip An important Magnesium Magnesium CNS Depressants— Parenteral administration
Sulfate electrolyte with cofactor for sulfate is also sulfate should not When barbiturates, should be used with
(Epsom salt) replacements D5LR enzymatic used to prevent be administered narcotics or other caution in nursing
/ 1000cc reactions and or treat parenterally in hypnotics (or women since it can be
supplements + 10g plays an magnesium patients with systemic distributed through milk.
important role deficiency in heart block or anesthetics), or other
in patients myocardial CNS depressants are
neurochemical receiving total damage. to be given in
transmission parenteral conjunction with
and muscular nutrition. magnesium, their
excitability. dosage should be
Magnesium adjusted with
prevents or caution because of
controls additive CNS
convulsions by depressant effects of
blocking magnesium. CNS
neuromuscular depression and
transmission peripheral
and decreasing transmission defects
the amount of produced by
acetylcholine magnesium may be
liberated at the antagonized by
end plate by the calcium.
motor nerve
impulse.
Magnesium is
said to have a
depressant
effect on the
central nervous
system (CNS),
but it does not
adversely affect
the mother,
fetus or neonate
when used.
Magnesium acts
peripherally to
produce
vasodilation.
With low doses
only flushing
and sweating
occur, but larger
doses cause
lowering of
blood pressure.