Receptor Selected action

Agonist potency order Agonists Antagonists

type of agonist

(Alpha-1 agonists) (Alpha-1 blockers)

 Doxazosin
 Noradrenaline  Phenoxybenzamine

α1 adrenaline ≥ noradrenaline >>

isoprenaline
smooth muscle contraction



Phenylephrine
Methoxamine
Cirazoline
 Phentolamine
 Prazosin
 Tamsulosin

 Xylometazoline  Terazosin

(Alpha-2 agonists)
(Alpha-2 blockers)
 Yohimbine
 Clonidine
 Idazoxan

α2 adrenaline ≥ noradrenaline >>

isoprenaline
smooth muscle contraction and
neurotransmitter inhibition



Guanafacin
Monoxidine
Alpha.methydopa
 Tolazoline
 Rauwolscine

 .
 Guanfacine

 Noradrenaline
 Metoprolol
β1 isoprenaline > adrenaline =
noradrenaline
heart muscle contraction



Isoprenaline

Dobutamine
 Atenolol

 Salbutamol, Albuterol
(Beta blockers)
 Bitolterol mesylate
 Butoxamine
 Formoterol
 Propranolol
 Isoprenaline
 Nadolol

β2 isoprenaline > adrenaline >>

noradrenaline
smooth muscle relaxation



Levalbuterol
Metaproterenol
Salmeterol
 Carteolol
 Timolol
 Sotalol
 Terbutaline

 Ritodrine

 Amibegron
β3 isoprenaline = noradrenaline >
adrenaline
Enhance lipolysis
 Solabegron