FOREIGN ANTIGENS

Nose
Nose

Bind with IgE

Mast Cells Basophils

Granules the mast cells and basophils

result to release of receptor

Accumulation Increased Dilatation of blood vessel and Increases Increase mucus production
of neutrophils blood flow capillary permeability of the goblet cells

Mucus accumulation occurs

Inflammation of Inflammation of small
Release of endogenous because of lack of cilia due to
mucosal membrane airways metaplasia
pyogenes

Provide breeding ground for

Set hypothalamus to Narrowing of small Small airway microorganism growth
Nasal Obstruction of
increase body airways obstruction
congestion small nasal
temperature Microorganism invade cell
passages
lining of the small airways

Fever Cell death of small

Accumulation of discharges in
the nasal cavity Air trapping airways
Impaired gas
exchange apnea
Runny nose or stuffy
nose
No ica nd l
Impending

m no oid or
Increase air

n- tion No
ed l a
Ty

as
le ter mat
resistance in the respiratory

pi like -
Br Tria

rin
airways
s
in ag
fla en to onc l do
failure
m of an re h se
ief n c in du odil of
a

n
l fla ce at
Re stio ned m o
i m airw rs
ts

e
y
ng tta h ati
co e a oug ing a
on y Wheezin
b hr
t tion g
c
su

Hy lutio ase of s
pe n
Hypoxemia Dyspne

So incr tion tio

hypercapnia

rto for
a

ni
hy s s

c
m

dr ec
e
uc

a
u
Increase anterior posterior chest Decrease blood pH Hypoxia Use accessory

re
diameter muscles

n
Cyanosis
Hyperinflation of Respiratory Acidosis
the lungs

in -
avir anti
b )
Ri ole
z A
ir DN tion
a
(V ica
e pl
Chest Fatigue r
retractions

Pr irw ve s
A siti ou
Po tinu
n
Co

es ay
re
su