PALAWAN STATE UNIVERSITY

COLLEGE OF NURSING AND HEALTH SCIENCES

PUERTO PRINCESA CITY

DRUG STUDY
NAME OF
DRUG

Diclofenac

CLASSIFICATION

DOSE,
FREQUENCY
AND ROUTE

Antiinflammatory
NSAID

500
/tab
,PO

MECHANISM OF
ACTION

mg Unclear.
TID Thought
to
block activity
of
cycooxygenas
e , thereby
inhibiting
inflammation
responses of
vasodilation
and swelling
and blocking
transmitions
of
painful
stimuli

INDICATIONS

CONTRAINDICATIONS

SIDE EFFECTS AND

ADVERSE
REACTIONS

NURSING
RESPONSIBILITIES

Analgesia,
Dysmenorrhe
a, rheumatoid
arthritis,
osteoarthritis
ankylosing
spondylitis

Hypersensitivit
y to drug or
its
components,
other NSAIDs,
or aspirin
Active
GI
bleeding
or
ulcer disease

CNS:
headache,
dizziness,
drowsiness
CV: hypertension
GI:
diarrhea,
abdominal
pain,
dydpepsia, heart
burn, peptic ulcer,
GI bleeding
GU:
dysuria,
frequent
urinations,
nephritis
Hepatic:
hepatotoxicity
Skin: rash, contact
dermatitis

1.Assess
for
hypertension
2. monitor hepatic and
renal function
3. Observe for and report
signs and symptoms of
bleeding

Patient teaching
1. instruct patient to
take a drug on empty
stomach for 1 hour
before or after a meal
2. advice patient not to
lie down for 15 to 30
minutes
after
taking
drug,
to
minimize
esophageal irritation
3. instruct patient to
immediately report signs
Page | 17

or
symptoms
hypersensitivity
reaction .

PALAWAN STATE UNIVERSITY

COLLEGE OF NURSING AND HEALTH SCIENCES
PUERTO PRINCESA CITY

DRUG STUDY
NAME OF
DRUG

CLASSIFICATIO
N

DOSE,
FREQUENCY
AND ROUTE

MECHANISM OF
ACTION

INDICATIONS

CONTRAINDICATIONS

SIDE EFFECTS AND

ADVERSE
REACTIONS

NURSING
RESPONSIBILITIES

Page | 18

of

Ampicillin

Antibiotic
Penicillin

May
be
given
IV,
IM or PO.
Use
parentarel
routes
severe
infections,
and switch
to
oral
route
as
soon
as
possible.

Bactericidal
action against
sensitive
organism;
inhibits
synthesis
of
bacterial cell
wall, causing
cell death.

Treatment of
infections
caused
by
susceptible
strains
of
Shigella,
salmonella, E.
coli,
H.
influenza,
P.
mirabilis,
N.
gonorrhea,
enterococci,
gram-positive
organisms( pe
nicillin
Gsensitive
staphylococci,
sterptococci,
pneumococci)
Meningitis
cause
by
Neisseria
meningitidis
Unlabeled
use:
Prophylaxis in
cesarean
section
in
certain
high

Contraindicate
d with allergies
to
penicillin
cephalosporins
,
or
other
allergens.
Use cautiously
woth
renal
diorders.

CNS:
Lethargy,
hallucinations,
seizure
CV: CHF
GI:
glossitis,
stomatitis,
gastritis,
sore
mouth,
furry
tongue,
black
hairy
tongue,
nausea, vomiting,
diarrhea,
abdominal
pain,
bloody
diarrhea,
enterocolitis,
pseudomembrano
us
colitis,
nonspecific
hepatitis
GU: Nephritis
Hematologic:
Anemia,
thrombocytopenia,
leukopenia,
neutropenia,
prolonged
bleeding time
Hypersensitivity:
Rash,
fever,

Instruct the patient to

take this drug around
the clock.
Advice the patient to
take full course of
therapy; do not stop
taking the drug if you
feel better.
Instruct the patient to
report
pain
or
discomfort at sites,
unusual bleeding or
bruising , mouth sores
, rash ,hives, fever,
itching
,
severe
diarrhea,
difficulty
breathing.

Page | 19

risk patients.

wheezing,
anaphylaxis
Local:
Pain,
phlebitis,
thrombosis
at
injection
site( parenteral)
Other:
superinfectionsoral and rectal
moniliasis,
vaginitis

Page | 20