ScienceLeadershipAcademy

G10Bio/Chemistry

GeneticsProject

AIM:
Youwillcollaboratewithyourteamtoresearchandpresentageneticcondition.Yourwork
shoulddemonstratethatyouunderstandhowtraitsareinherited,andhowchangestoourgenes
canaffectthebody.

Part1:Groupwork

(allofthisshouldbeinyourgroupgoogledoc.)

1. DescriptionProvideanoverviewofthiscondition.Whatarethesymptoms?Howdidit
getitsname?Whatisthisconditionshistory?Giveanexampleofareallifepersonwho
has/hadthiscondition.
2. GeneticchangesDiscusshowthegene(s)associatedwiththeconditionis/aredifferent
fromthenormalgene(s).Howdoesthegeneticconditionalterbiochemicalprocessesor
reactions?Whichproteinsareaffected?Howdoesthisaffectthebodyoverall?
3. DiagnosisHowdowetestforthisconditionand/ordetermineifsomeoneisaffectedwith
thiscondition?Referbacktothepersonyoumentionedinpart1.
4. Treatment/RecommendationsOncesomeoneisdiagnosed,whatdowedo?Again,
referbacktoyourcasestudyexample.
5. InheritancepatternIsitrecessive,dominant,sexlinked,codominantorincomplete
dominant?Whatdoesthismean?Explainhowyourcasestudyinheritedthiscondition.

Part2:Individualwork
6. Provideatleast5Punnettsquareexamples,listingallgenotypes,phenotypes,and
percentchanceofeach.
7. FirstPedigreechartShowasamplepedigreeofafamilywiththiscondition(couldbe
yourcasestudy,oranimaginaryfamily).Atleastoneparentingeneration2musteither
beacarrieroranaffectedindividual.
Downloadblankpedigreesheethere.
8. SecondPedigreechartShowasamplepedigreewithyourselfandacelebrityspouse
foraspecifictraitthatyouchoose(bloodtype,curlyhair,etc).

Part3:Teachtheclass
Afterresearchingageneticcondition,youwillthenteachtheclasswhatyouhavelearned
using
acasestudyasanexample(thisisthereallifepersonwhohas/hadthecondition)
.
1.Yourlessonshouldcoverandinclude:
a)Allthethingslistedundergroupwork(Donotcopyandpaste,summarizeyourwork).
b)Anactivityoranassignment(suchaspracticepunnettsquareproblems,apedigree,etc.).
2.Alloftheworkforthelessonshouldbeonthegoogledoc(thisincludesanynotesyouwrote
downforyourselfandanyhandoutsyoumayhavemade).

Collaboration
:Onepersoninyourgroupshouldcreateagoogledocandshareitwith

everyoneelse.Eachindividualshouldputthisgoogledocintheirbiochemfolder.Youshould
eachchooseacolortouseonthisdocument,andnotewhichgroupmemberscorrespondto
eachcoloratthetopofyourdocument.Yourgroupwillusethisdocumentforplanning,writing
drafts,andpossiblyturninginyourfinalproduct.Thegoalistobeabletoseeequal
contributionsfromeachpartner.

SincecollaborationisoneofSLAscorevalues,itsveryimportantthatwelearnhowtowork
welltogether.Ifyourgroupishavingtroubles,youneedtoletmeknowASAP.Ifyouwaituntil
thedaybeforetheprojectisdue,Iwontbeabletohelpyou.

Thinkofitthisway:Ratherthandividetheprojectinto4parts(oneforeachstudent),have
each
groupmemberworkon
each
part.Thiswillproduceabetterproject,and,moreimportantly,will
resultineveryonelearningmore!Also,thiswillensurethateachmemberofthegroupis100%
comfortablewiththefinalsubmittedproduct.

ImportantNotes:
Anyformofplagiarismwillresultina0forthisbenchmark,asoutlinedinSLAs

academic
integritypolicy
.Also,sincethisisagroupproject,thefollowingpartofouracademicintegrity
policyisimportant:Ifagroupprojectissubmittedthatcontainsplagiarizedorcopiedwork,
othergroupmemberswhodidntplagiarizewillbepenalizedonefulllettergrade(10%)forthe
project,andthegroupmemberwhoplagiarized/copiedwillfallundertheaboveconsequences.
Ifthereisaconcernaboutagroupmemberpossiblyplagiarizingornotcompletinghisorher
shareofagroupswork,othergroupmembersshouldvoicethisconcernwiththeirteacheras
earlyaspossible,andtheteacherwillworkwiththegrouptocomeupwithasolution.

The

GeneticsHomeReference
isagreatresource.

Checkpoints:
Checkpoint1:
Writtenfirstdraftforparts14(description,geneticchanges,diagnosis,
treatment/recommendations).Ongoogledoc,colorcodedtoshowwhodidwhat.

Checkpoint2:
a)5Punnettsquaresfromeachindividual,onpaper.

Checkpoint3:
a)Completedpedigreesfromeachindividual,onpaper.
b)Writtenexplanationofpart5(inheritancepattern).Ongoogledoc.

Checkpoint4(finalproject):
a)Useyournotes/draftsonthegoogledoctocreatealessonfortheclass,
thelessonshould

benomorethan10minutesbutatleast5minutes
.Thiscouldinvolveapresentation,
handouts,anactivity,etc.

Checkpoint5:
Reflectionafterteachingyourlesson,completeanindividualreflectiononcanvas.

Timeline(tobedetermined

Monday

Tuesday

Wednesday

Thursday

Friday

11/16

Au:introproject

11/17

Ag:introproject

11/18

11/19

11/20

engineering

11/23

Checkpoint1

11/24

11/25

11/26

NoSchool
Thanksgiving

11/27

NoSchool

11/30

12/1

12/2

12/3

12/4

engineering

12/7

12/8

12/9

12/10

12/11

12/14

12/15

12/16

12/17

12/18

Rubric:

2019:exceedscriteria
1816:meetscriteria
1513:approachescriteria
120:doesnotmeetcriteria

Category

MeetsExpectations

Points

Design

Presentation/lessondeliversnecessarycontentina
logicalandappropriatefashion.

Application

Acasestudyisusedasanexampleofsomeonewiththis
geneticcondition.Basicgeneticknowledgeisappliedto
thiscasestudytoindicateinheritance,treatments,
symptoms,etc.

Knowledge

Explanationofthegeneticscausingtheconditionis
thoroughandcorrect.

Presentation

Presentation/lessonmaterialsarevisuallyappealingand
aidintheteachingprocess

Process

Individualreflectionshowsdeepunderstandingofthe
processofcompletingthisproject.

Total

SuggestedConditions:

InheritancePattern

PossibleDisorders

Recessive

TaySachs
Phenylketonuria(PKU)
CysticFibrosis
Canavandisease
Congenitalinsensitivitytopain
otherwithapproval

Dominant

Dwarfism
HuntingtonsDisease
Marfanssyndrome
CongenitalHypoventilationSyndrome(Ondinessyndrome)
otherwithapproval

Codominant

Bloodgroups(nottechnicallyadisorder)
Sicklecellanemia
otherwithapproval

Sexlinked

Baldness

Hemophilia
Kennedysdisease
ColorBlindness
HemophiliaA/B
Duchennemusculardystrophy
VitaminDresistantRickets
otherwithapproval
Incompletedominance

Wavyhair
otherwithapproval