Sei sulla pagina 1di 3

Patofisiologi

dan manifestasi klinis

Precipitating factor

Predisposing
factors

Plaques/ Deposits of Nicotine


on veins
Inflamation of the small and medium-sized arteries and veins of
the extremities
Thickned artery and
veins
Platelets Deposits on the
thickned artery

Fibrinoid
Occlusion
Impairmend blood
supply
Early sign and
symptomps
Claudication type of
pain
Color Changes
(Pallor)
Temperature
Changes
Cold Sensitivity
( Reynauds
Phenomena)
Ulceration
Gangrene

Ischemia

Injury to blood
vessels
Necrosis

Advance/ late sign and


symptomps
Thrombophlebitis
with trauma
Ulceration
Gangrene
Pulsation of the
extremities involed
are weak or absence
Color changes
( Cyanotic)

Potrebbero piacerti anche