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Non-contact Tissue
Viability Diagnosis Device
Group 31
Presenter: Yoga Shentu
Team members: Xinzi Wang, Zhijie Qi
Client: Brady Clay

Background

10,000 cases of amputations per

year

94% involves finger

Replantation success rate >80%

Key: proper vascularization

Current diagnosis: Oximeter

Image Source: Operative Techniques in Hand, Wrist, and Forearm Surgery

Background

Limitation

Single spot

Cant operate on incision

Pressure on the tissue

Image Source: http://theladdermn.org/

Nonin Medical Inc.

Needs

Non-contact

Non-invasive

Monitor large area

Can operate on incision site

Handheld

Existing Solutions

Red blood cell flow

Partial pressure of O2

Oxygen level

Red Blood Cell Flow

Laser Doppler Imaging (LDI)

Laser Doppler Imaging of Skin Blood Flow for Assessing Peripheral Vascular Impairment in Hand-Arm Vibration Syndrome. Industrial Health. 2007:45:309317

Partial Pressure of O2
Transcutaneous Oximetry

Image source: http://www.perimed-instruments.com/transcutaneous-oxygen---tcom-tcposub2sub

Existing Solutions

Red blood cell flow

Partial pressure of O2

Oxygen level

Sensing Oxygen
Technique

Materials

Imaging of radioisotopes

PET scanner;
radioactive tracers

Resonance imaging

MRT or EPR scanner; contrast

agents

Optical StO2 measurements

optical systems

Phosphorescence quenching

sensor dyes, optical devices

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Existing Patent
US 20030139667 A1

Light source emitting in the wavelength region between 400-2500 nm

Detector measures wavelength data from the remitted light.

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Existing Patent
EP 0481612 A1

Disposable, flexible, adhesive member that includes radiation detector

Reusable member that includes electromagnetic radiation emitter.

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Project Scope

Non-invasive device to measure peripheral skin tissue viability

Real-time feedback

Monitor metabolic indicator in the incision area

Record, transmit data

Software interpret data and output plot

Mockup and software will be delivered

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Design Requirement
Design aspect

Specific requirement

Operation temperature

15 C to 30 C

Operation humidity

20% to 85%

Device dimensionality

< 13cm x 10cm x 15cm

Device mass

<500g

Output indication spatial resolution

< 1mm

Data sampling speed

> 5 cm2/s

Device cost

< $600

Software operation speed

<1 min between data input and result output

Software memory utilization

< 100M

Device lifespan

> 5 years

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Team Members

Xinzi Wang

electrical system

Metabolic indicator
literature research

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Team Members

Zhijie Qi

Programming

Software development

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Team Members

Yoga Shentu

Existing patents

Products on market

Build mockup device

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Client

Brad Clay

Principal Engineer at bioMerieux, Inc.

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Design Schedule