Pathophysiology

Graves Disease (Autoimmune)

Release of Thyroid stimulating

antibodies

Anterior Pituitary Glands release of

Thyroid Stimulating Hormone (TSH)

Thyroid Glands stimulation of

producing
T3 and T4 in normal amount

Presence of Thyroid
Secreting Pituitary Tumor

Increased TSH production

Facilitation of normal
metabolism process

Increased T3 and T4 in the blood

HYPERTHYROIDISM

Increased oxygen
consumption

Increased body heat

production

Increased
metabolism

Increased cellular
metabolism

Insomnia
Restlessness
Fatigue
Irritability
Tremors
Nervousness
Hyperactivity

Heat intolerance
Diaphoresis
Red, flushed and warm
to touch skin

Weight loss in spite

of
increased appetite

Increased vital
signs and peristaltic
movement