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Tetramethylthiuram disulfide / thiram

Thiram is a fungicide, ectoparasiticide, and animal repellent. It is used to


prevent fungal diseases in seed and crops. It is also used as an animal
repellent to protect fruit trees and ornamentals from damage by rabbits,
rodents and deer. It is effective against Stem gall of coriander, damping off,
smut of millet, neck rot of onion, etc. Thiram has been used in the treatment
of human scabies, as a sun screen and as a bactericide applied directly to the
skin or incorporated into soap.
It is available as dust, flowable, wettable powder, water dispersible granules,
and water suspension formulations and in mixtures with other fungicides.
Thiram is irritating to the eyes, skin and respiratory tract. It is a skin
sensitizer. Symptoms of acute inhalation exposure to thiram include itching,
scratchy throat, hoarseness, sneezing, coughing, inflammation of the nose or
throat, bronchitis, dizziness, headaches, fatigue, nausea, diarrhea and other
gastro-intestinal complaints. Persons with chronic respiratory or skin disease
are at increased risk from exposure to thiram. (acute toxicity)
exposure to thiram in humans include drowsiness, confusion, loss of sex
drive, incoordination, slurred speech and weakness. Repeated or prolonged
exposure to thiram can also cause allergic reactions such as dermatitis,
watery eyes, sensitivity to light and conjunctivitis.(chronic toxicity)

Tetraethylthiuram disulfide
The tetraethylthiuram disulfide compound, known as Disulfiram, is commonly
used to treat chronic alcoholism by producing an acute sensitivity to alcohol
ingestion by blocking acetaldehyde dehydrogenase conversion of
acetaldehyde leading to a higher concentration of the aldehyde in the blood
producing symptoms of a severe hangover.
Can detect this chemical reaction by using patch test.

Colophony/resin
is a solid form of resin obtained from pines and some other plants, mostly
conifers, produced by heating fresh liquid resin to vaporize the volatile liquid
terpene components.
Rosin is an ingredient in printing inks, photocopying and laser printing paper,
varnishes, adhesives (glues), soap, paper sizing, soda, soldering fluxes, and
sealing wax.
Prolonged exposure to rosin fumes released during soldering can cause
occupational asthma (formerly called colophony disease[11] in this context)
in sensitive individuals, although it is not known which component of the
fumes causes the problem.

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