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Cerebellar disorders

Some activities require


MORE COORDINATION

Relevant Points in the HISTORY:


- Frequent falls
- Clumsiness & difficulty with fine
coordinated movements
- Tremors
- Waxing & Waning of symptomsMS
- Stroke- Drug toxicity: Phenytoin, alcohol
abuse, lead poisoning & solvent abuse
- History of HYPOTHYROIDISM
- F.H--------FA & other hereditary ataxias

SIGNS

HYPOTONIA

Cerebellar
Ataxia

Causes: 1-Inhereted

Autosomal recessive
Progressive degeneration of dorsal root ganglia,
spinocerebellar tracts, corticospinal tracts and
cerebellar Purkinje cells.
Chromosome 9q13
Fraxatin
Progressive difficulty in walking occurs around
the age of 12. Death is usual before 40.

ataxia of gait and trunk


nystagmus (25%)
dysarthria
absent lower limb joint position and vibration
sense
absent lower limb reflexes
optic atrophy (30%)
pes cavus
cardiomyopathy.

ATAXIA TELANGIECTASIA

2.DEVELOPMENTAL
ARNOLD-CHIARI MALFORMATION
BASILAR INVAGINATION
CEREBRAL PALSY

3-VASCULAR

BLOOD SUPPLY
Superior surface-SUPERIOR
CEREBELLAR
Branch of BASILAR Artery

Inferior surface Anterior part:


ANTERIOR
INFERIOR CEREBELLAR
Branch of BASILAR Artery

Inferior surfacePosterior part:


POSTERIOR
INFERIOR CEREBELLAR
Branch of
VERTEBRAL Artery

VEINS: Straight sinus, Occipital


sinus, Transverse sinus

The Cerebellum is supplied by 3 major


arteries on each side:
1. PICA..The MOST common syndrome:
Lateral Medullary
syndrome.Wallenberg's
2. AICA, the second most common
syndrome
3. SCA; the least frequent syndrome

Wallenberg's Syndrome is typified by:


Vertigo
Ipsilateral hemiataxia
Dysarthria
Ipsilateral Horner's Syndrome (Central)
Most patients with this stroke
recover very well and often resume their
previous activities
Diagnosis is generally via MRI

Infectious:
- Abscess
- Acute cerebellitis---VIRAL
- Creutzfeldt-Jacob disease

Metabolic:
- Antiepileptic drugs
- CO poisoning
- Alcoholvitamin B1
deficiency
- Lead poisoning

4.Tumours

If you are allowed to perform ONE


investigation, which one you choose in a
Pt with a suspected cerebellar lesion?
MRI..

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