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Name: Jenna Babcock & Chris Gutierrez

Date: 10/2/14

Focus Question: What is the effectiveness of occupational therapy on improving occupational performance, participant wellness, lifestyle modification, and to improve
quality of life in individuals with Parkinsons disease.

Rationale for inclusion/exclusion criteria applied to determine which


articles should be included in the evidence table:
Inclusion:
Publications matching the focus question population, intervention, and
outcome.
Research participants must present with clinical diagnosis of PD
Level I-II evidence (systematic review, randomized control trial, two group
nonrandomized studies)
Articles published within the last 5 years (2009-present)
Written in English
Articles were published in peer-reviewed journals
Only adult participants

Exclusion:
Articles missing one or more of the inclusion category (participant wellness, lifestyle
modification, personal control to improve quality of life)
Level III-V studies (one group nonrandomized, case descriptive statistics, single
subject design, case reports, and expert opinion)
Articles prior to 2009
Qualitative studies
Written in another language other than English
Driving
Group OT
Expressive behaviors

Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

To determine
whether people with
relatively early and
mild PD have
difficulty with
cognitively
demanding IADLs.

Level II

Intervention:

Small sample size.

Cross-sectional,
descriptive design.

Nine IADLs were used


for this study:

People with
relatively early PD
demonstrated
measurable deficits
in the performance
of cognitively
demanding IADLs.

Clinical & community-based


practice of OT:

Year
Foster, 2014

1) Oven use
77 participants with PD
and 57 non-PD
participants.

2) Stovetop use
3) Sharp utensil use
4) Bill paying by check
5) Checkbook balancing

Strategies to support the


performance of IADLs &
other complex activities in
the early stages of PD may
allow people to maintain
their independence,
participation, and quality of
life longer and may even
slow the rate of functional
decline.

6) Mailing bills
7) Shopping

Program development:

8) Medication
management

Interventions focused on
activities that take place in
the home; looked at
performance of IADLs.

9) Small home repairs

Measures:
Performance Assessment
of Self-care Skills
(PASS)
MMSE for global
cognitive function
Beck Depression
Inventory II
Unified Parkinsons
Disease Rating Scale
(UPDRS)

Societal needs:
Many pts with PD may
benefit from OT services;
specific treatments for
IADLs will improve
independence.

Healthcare delivery & health


policy:
OT is an evidence-based

profession. These
interventions examined the
cognitive ability of the
individuals to accomplish
IADLs.

Education & training of OT


student:
OT students should be aware
of increasingly difficult
IADLs with PD pts and
treatment techniques.

Refinement, revision, &


advancement of factual
knowledge or theory:
Consider subdividing the cue
levels at the higher end of the
spectrum to increase
sensitivity. Exploration of
factors that distinguish those
with PD who did and did not
require cues is warranted.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

Review RCTs
reporting on the
effectiveness of
exercise
interventions on
outcomes (physical,
psychological or
social functioning,
or quality of life) for

Level I

Intervention:

Results identified
that exercise is of
benefit to people
with PD in respect
of physical
functioning,
HRQOL, strength,
balance and gait
speed. Findings add

Participants
mainly men &
raised question if
interventions were
acceptable to
women.

Clinical & community-based


practice of OT:

Year
Goodwin,
Richards, Taylor,
& Campbell,
2008

Systematic review and


Meta-Analysis

While looking at multiple


studies, two of the studies
evaluated an exercise
intervention against a
non-exercise control,
another compared two
different exercise

Exercise is critical to
improve PD pts QOL.

people with PD.

Each RCT had a


different amount of
participants within their
study.

interventions and another


study compared three
different exercise
interventions.

to the growing body


of evidence
regarding the
effectiveness of
physiotherapy for
people with PD.

Program development:
Evidence from this study
showed that there are many
benefits of utilizing exercise
with individuals with PD.

Measures:
Modified Jadad score

Societal needs:
Many PD adults do not
exercise due to difficulty
regarding mobility. Specific
exercises will help pts
improve mobility.

Healthcare delivery & health


policy:
It is important to implement
exercise to PD adults in order
to increase strength and
balance.

Education & training of OT


student:
OT students should be aware
of which strength and
balance exercises are
beneficial for PD pts.

Refinement, revision, &


advancement of factual
knowledge or theory:

Future research needs to


establish what elements
constitute an optimal
exercise intervention for
people with PD such as the
dosage, component parts of
intervention, and the targeted
stage of the disease. This is
of particular importance
given the deteriorating nature
of this condition.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

To investigate
whether body
weight-supported
treadmill training
(BWSTT) is of
long-term benefit
for patients with
Parkinsons disease.

Level I

Intervention:

The BWSTT group


had significantly
great improvement
over the PT group in
gait.. This was the
same for months 2
and 3 but at the 4
month mark.

Small sample size

Clinical & community-based


practice of OT:

Year
Miyai, Fujimoto,
Yamamoto,
Ueda, Saito,
Nozaki, & Kang,
20

RCT targeting
functional ambulation.

24 PD pts (12 men, 12


women) who
experienced freezing
phenomenon during
gait.

Pts were randomized to


receive either 45-minute
sessions of BWSTT or
45-minutes sessions of
conventional PT 3 days a
week for 1 month, for a
total of 12 sessions. Gait
speed and the number of
steps taken for a 10-m
walk were done at
baseline, 1, 2, 3, 4, 5, and
6 months.

Measures:
Unified Parkinsons
Disease Rating Scale
(UPDRS)

BWSTT has a lasting effect


on gait disturbance in PD
patients. BWSTT
specifically improved shortstep gait, which is a clinical
characteristic of PD, beyond
the time of the intervention.

Program development:
Improvement in the gait of a
PD individual helps for
functional ambulation to
complete many ADL and
IADLs.

Societal needs:
Many PD pts struggle with
short-step gait. Specific type

of step training would be an


effective treatment technique
for ambulation.

Healthcare delivery & health


policy:
BWSTT was specifically
effective in improving shortstep gait of PD patients. It is
possible that BWSTT
induces implicit motor
learning by enhancing such
alternative brain networks.

Education & training of OT


student:
OT students should be aware
of BWSTT treatment
techniques for adults with
PD.

Refinement, revision, &


advancement of factual
knowledge or theory:
To determine whether
reorganization of motorrelated areas also occurs
consistently after BWSTT.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

PD has a profound

Level I

Intervention:

This study

Small sample size.

Clinical & community-based

Year
Meek, Morgan,

Walker,
Furmston,
Aragon,
Birleson, &
Sackley, 2010

impact on a persons
ability to carry out
self-care and ADLs
resulting in
increased
dependence.

A pilot RCT
investigating
occupational therapy
for people with
Parkinsons disease
exhibiting difficulties
with activities of daily
living.

19 participants received
OT. The intervention log
demonstrated that a large
proportion of therapist
visits involved equipment
provision/environmental
adaptation,
mobility/transfers/ADL
training,
review/discussion, and
the teaching of
techniques/provision of
education.

confirmed the
feasibility and
acceptability of an
individualized,
community-based
OT intervention for
people with PD
experiencing
difficulties with
ADLs.

practice of OT:
Individualized and
community-based OT
treatment utilizing adaptation
and education is beneficial
for adults with PD.

Program development:
Individualized OT treatment
regarding ADLs is beneficial
for pts with PD.

Measures:
Nottingham Extended
Activity of Daily Living
Scale (NEADL)
Rivermead Mobility
Index (RMI)
Unified Parkinsons
Disease Rating Scale
(UPDRS)
Parkinsons Disease
Questionnaire 39 (PDQ39)
EuroQol-EQ-5D (EQ5D)

Societal needs:
Many adults with PD are not
able to conduct ADLs
independently and need
assistance from adaptation
techniques and
modifications.

Healthcare delivery & health


policy:
Evidence suggests that
individual OT treatments
regarding environmental
modifications/transfers/ADL
training/education are
effective for PD pts.

Education & training of OT

student:
OT students should be aware
of which ADLs are difficult
for each PD pt and
knowledge of adaptations for
environment.

Refinement, revision, &


advancement of factual
knowledge or theory:
Although the intervention log
was successful in capturing
some broad aspects of
treatment, the trial also
highlighted that techniques
used during therapy may be
useful.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

Determine if
increasing hours of
self-management
rehab had increasing
benefits for healthrelated quality of
life (HRQOL) in PD
beyond best medical
treatment.

Level I

Intervention:

Six weeks there was


a beneficial effect of
increased rehab
hours on HRQOL
measured with the
Parkinsons Disease
Questionnaire-39
summary index.
Benefits persisted at
follow-up.

This study did not


differentiate the
active
contributions of
rehab methods.

Clinical & community-based


practice of OT:

Year
Tickle-Degn,
Ellis, SaintHilaire, Thomas,
& Wagenaar,
2010

117 pts assessed on


HRQOL at baseline,
immediately post
intervention at six
weeks, and at two
months and six months
follow-up.

Each group clinic session


involved physical
exercises, speech
exercises, functional
training, and a discussion
about self-management
strategies. Pts were
taught to problem solve
by asking themselves a
key question: Can I
change something about
myself, about the task, or
about the environment to
improve my ability?

Implementation of various
exercises and education
provided pts to become more
efficient with selfmanagement.

Program development:
This intervention allowed pts
to utilize tools in order to
problem solve.

Societal needs:
PD adults tend to be deficit
with ADLs. Education and
training helps improve adults
function.

Measure:
Parkinsons Disease
Questionnaire-39
Summary index score

Healthcare delivery & health


policy:
Each intervention session
was effective in improving
pts with problem solving
when conducting functional
activities.

Education & training of OT


student:
OT students should be aware
of which education
techniques enable PD pts to
conduct ADLs more
efficiently.

Refinement, revision, &


advancement of factual
knowledge or theory:
Improvement rates
anticipated to be 20% to 53%
greater than for medication
alone.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

Year
Protas, Mitchell,
Williams,
Qureshy,
Caroline,& Lai,
2005

To assess the benefit


of gait and step
perturbation training
in individuals with
PD.

Level I

18 men with idiopathic


PD diagnosed at the
Houston VA
Parkinsons Disease
Research, Education
and Clinical Center
(PADRECC).

Intervention:
Subj were tested in the
morning and asked to
take meds 1 hr prior to
the test in order to assure
that subjects were at their
best. Gait was assessed
by gait speed, cadence, &
stride length. Pt
completed 2 trials on the
walkway and average
speed calculated. Pts
received training 3 times
per wk for 8 wks.

Substantial
reduction occurred
in falls in the
trained group, but
not in the control
group. Gait speed
increased in the
trained group but
not in control group.
Stride lengths
increased for the
trained group but
not for the control
group.

Sample size was


small, especially
given the
variability in
individuals with
PD.

Clinical & community-based


practice of OT:
Gait and step perturbation
training with PD pts is
effective for reducing falls
when ambulating in
environment.

Program development:
Evidence should be used
regarding the step and gait
training when conducting
ADLs and IADLs.

Measures:
Self-report for falls
Neurobehavioral
Cognitive Status
Examination
Hoehn & Yahr staging

Societal needs:
Pts with PD often have an
increased risk of falling and
decreases their self-efficacy
of moving in their
environment, decreasing
their QOL.

Healthcare delivery & health


policy:
Interventions reduced pts
risk of falling and increased
strength and balance. This
rehab tool can be
implemented with OT
sessions.

Education & training of OT


student:
OT students should be aware
of training and
implementation of step and
gait techniques when
conducting ADLs and
IADLs.

Refinement, revision, &


advancement of factual
knowledge or theory:
Due to this studys small
sample size, further research
should focus on larger
sample size.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

To perform a pilot
trial of OT to
optimize functional
independence in PD
in order to assess
accrual/withdrawal
rates, acceptability,
outcome measures,
& inform samplesize calculation.

Level I

Intervention:

Minimally relevant
changes in NEADL
and PDQ-39.

The small pilot


study was not
intended to
provide definitive
data on the
effectiveness of
occupational
therapy for ADL
problems in
Parkinsons
disease, rather to
inform design of
future RTCs.

Clinical & community-based


practice of OT:

Year
Clarke,
Furmston,
Morgan, Patel,
Sackley, Walker,
& Wheatley,
2009

RCT with masked


assessment of standard
community-based
individual OT targeting
functional
independence and
mobility.

Pts were divided into two


groups. One group was
assessed at home and
then received six home
treatments sessions over
2 months. The other
group would not receive
any treatment sessions.
At 2 and 8 months post
randomization,
assessments were posted
to all pts for selfcompletion.

Benefits of OT functional
dependency is cost-effective
and better service provision
for pts with PD.

Program development:
This intervention had a short
time frame. More effective
OT sessions are needed to
determine effectiveness of

OT services over longer time


period.
Measures:
Nottingham Extended
Activity of Daily Living
Scale (NEADL)
Rivermead Mobility
Index (RMI)
Unified Parkinsons
Disease Rating Scale
(UPDRS)
Parkinsons Disease
Questionnaire 39 (PDQ39)
EuroQol-EQ-5D (EQ5D)
Hospital Anxiety and
Depression Scale
(HADS)

Societal needs:
PD pts are often deficit with
ADLs in their homes.
Specific home treatment
sessions provide pts with
increased independence.

Healthcare delivery & health


policy:
Home-based OT is a
common treatment, and
insurance companies
regularly pay for this
intervention. This study does
not have any implications in
regards to healthcare delivery
or health policy, beyond
offering additional evidence
that home-based OT is an
effective treatment for pts
with PD.

Education & training of OT


student:
OT students need to be aware
of how to implement
environmental modifications
for individualized clients and
their homes.

Refinement, revision, &


advancement of factual
knowledge or theory:
The results of the study
reviewed here support the
use of home-based OT
treatment as an intervention
for pts with PD. However,
this small pilot study was not
intended to provide definitive
data on the effectiveness of
occupational therapy for
ADL problems in PD, rather
to inform design of future
RTCs.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

PD affects pts
occupational
performance; this
study aims to
identify if OT is
beneficial for PD
pts.

Level I

Intervention:

Primary outcome
measures at three
months
demonstrated a
small positive trend
in favor of the
intervention group.
COPM measure
indicated that pts &
caregivers were
mostly or absolutely
satisfied with the
results of the
intervention. Was
not statistically
significant.

OTs treated a
relatively small
number of pts
each. OTs stated
interventions need
to be longer than
10 weeks.

Clinical & community-based


practice of OT:

Year
Sturkenboom,Gr
aff, Borm,
Veenhuizen,
Bloem,
Munneke, &
Nijhuis-van der
Sanden, 2013

Random allocation of
intervention 2:1
control, & an assessorblinded postintervention
measurement at three
months followed by a
qualitative evaluation
of the intervention
procedures & outcome.

OT services included
individualized
interventions for pts &
caregivers. The control
group did not receive any
OT intervention until
after the three months
measurement.

Measures:
COPM
AMPS
Consumer Quality index

OT interventions lead PD pts


to more self-efficacy w/
occupational performance.

Program development:
Based on this study, the
intervention of individualized
OT services should be
implemented for pts with PD.
The results indicate that pts
and caregivers were
absolutely satisfied with the
treatment.

Societal needs:
PD adults often function
within their own homes and
would benefit from homebased therapy compared to a
traditional rehab facility.

Healthcare delivery & health


policy:
Results indicate the
satisfaction of pts and
caregivers with OT
interventions, however,
treatments need to be longer
than 10 weeks.

Education & training of OT


student:
OT students should be aware
of how to conduct home
modification evaluations for
PD pts and develop
individualized treatment
plans.

Refinement, revision, &


advancement of factual
knowledge or theory:
Due to this studys small
sample size and limited
amount of time, further

research is needed to
determine if interventions
implemented will continue
longer than 10 weeks.
Author/

Study Objectives

Level/Design/ Subjects

Intervention and
Outcome Measures

Results

Study Limitations

Implications for OT

Pts QOL when


performing
ADLs/IADLs with
PD.

Level I

Intervention:

At 3 and 6 months,
intervention group
had significantly
better self-perceived
performance on
prioritized activities
(COPM) compared
to the control group.

Control group was


not offered an
intervention,
cannot exclude if
placebo effects
contributed to the
benefits
experienced by pts
in the intervention
group. Results
presented here
focused on
efficacy.

Clinical & community-based


practice of OT:

Year
Sturkenboom,
Graff, Hendriks,
Veenhuizen,
Munneke,
Bloem, & der
Sanden, 2014

RCT in ten hospitals,


using assessment at 3
and 6 months. 191
eligible pts who were
randomly assigned and
have PD and selfreported difficulties in
ADLs along with
caregivers.

Intervention group
received 10 weeks of
home-based OT.
Intervention strategies
were individually tailored
to alleviate the problems
in activities prioritized by
the pt.

Measures:
COPM for perceived
activity performance

OT intervention group
significantly improved pts
self-perceived performance
in meaningful daily
activities.

Program development:
It would be beneficial to
implement intervention
strategies based on the pts
prioritized problems. These
interventions are individually
tailored to alleviate problems
associated with PD.

Societal needs:
Many PD pts have different
priorities regarding ADLs
that are most affected. Homebased OT treatments are
most effective.

Healthcare delivery & health

policy:
Results of this study
indicated better selfperceived performance on
prioritized activities.

Education & training of OT


student:
OT students should be aware
of how PD affects each pt
individually in their home
environment and how to
implement adaptations in
order to be more efficient w/
ADLs.

Refinement, revision, &


advancement of factual
knowledge or theory:
In order for PD pts to feel
self-efficacy when
performing ADLs, OT
treatments need to be
measured and researched.

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