IBRO-TIFR

Neuroscience Symposium-PROGRAM

Tuesday - February 3, 2015 Venue: Faculty Lounge

Global Advocacy in APRC Region
9.00

Opening remarks by Keiji Tanaka (Chair, APRC)

9.10

Global Advocacy activities in IBRO (Sten Grillner)

10.00

Situations of neuroscience funding and research in individual countries 1

Japan (Tadashi Isa)

Korea (Yoo-Hun Suh)
China and Hongkong (Y.S. Chan)
Taiwan (Ding-I Yang)

12.00

Lunch Break

13.00

Situations of neuroscience funding and research in individual countries 2

Malaysia (Pike-see Cheah)

Singapore (S. Thameem Dheen)
Australia (John Rostas)
India (Upinder S. Bhalla)
Sri Lanka (Ranil De Silva)
Iran (Saeed Semnanian)

16.30

Coffee Break

17.00

Discussion on possible collaboration of global advocacy in APRC region

18.00

Indian Dance Program - Kathak by students of the Beej School

Venue: Homi Bhabha Auditorium Foyer

18.30

Departure from A Block Reception for Banquet Dinner

19.00

Banquet Dinner at Konkan Caf, Vivanta by Taj President

Wednesday - February 4, 2015 Venue : AG66

IBRO-TIFR Neuroscience Symposium
9.00

Opening remarks by Keiji Tanaka (Chair, APRC)

9.10

Plenary lecture: The Computational Logics of Network in Motion from

Microcircuits to Selection of Behaviour by Sten Grillner

10.00

Lecture 1: What Does Our Visual System Know about the World? by S.P. Arun

10.35

Lecture 2 : Developmental Plasticity of Vestibular Circuits Regulates

the Behavioral Outcome of Spatial Coding by Ying-Shing Chan

11.10

Coffee Break

11.30

Lecture 3: Functional Division among Prefrontal Areas of Macaque Monkeys by

Keiji Tanaka

12.05

Lecture 4: Pathogenesis and Therapy for Alzheimers Disease (AD) and Parkinsons
Disease (PD) by Yoo-Hun Suh

12.40

Lecture 5: Large-scaled Network Reorganization during Recovery from Partial

Spinal Cord Injury by Tadashi Isa

13.15

Lunch Break

14.15

Lecture 6: Early Adverse Experience and the Development of Psychopathology by

Vidita A. Vaidya Lecture 6: Ischaemia-Induced Neuronal Cell Death is Mediated by
Molecular Targeting of CaMKII Phosphorylated at T253 by JAP Rostas

14.50

Lecture 7: Controlling flow of synaptic vesicles in neurons by Sandhya Koushika

15.25

Lecture 8: Ischaemia-Induced Neuronal Cell Death is Mediated by Molecular

Targeting of CaMKII Phosphorylated at T253 by JAP Rostas

16.00

Colloquium: Molecular-motor transport in cells: what is the importance of motor

number, and how might this be regulated? by Steven Gross

17.00

High Tea

18.00

Indian Music Program - Pritam Bhattacharjee, Indian Classical vocalist from

Mewati Gharana.
Venue: Homi Bhabha Auditorium Foyer

20.00

Banquet Dinner at TIFR Almond Groove

Why the Brain?

- why advocacy?

Sten Grillner
IBRO

The HUMAN BRAIN is the challenge

of the 21st century

It is an electrochemical machine that enables us to think,

perceive, act and remember that consists of:
100 000 000 000 nervecells
10 000 000 000 000 synapses (contact points)
nervecells form functional modules/networks that
subserve different functions
Energy efficient runs on 30 60 watts
Diseases of the nervous system causes 35% of the
costs for healthcare in North-America and Europe

Sten Grillner
INTERNATIONAL BRAIN RESEARCH ORGANIZATION

IBRO Organiza9on

Founded in 1961, IBRO is governed by

an Execu9ve CommiIee and a Governing Council.

IBRO Mission
develop, support, coordinate and promote
scienti2ic research in all 2ields concerning
the brain
Promote neuroscience through interna0onal
collabora0on and global interchange of
scien0c informa0on
provide for and assist in educa0on and
dissemina0on of informa0on rela0ng to
neuroscience research

IBRO Membership
Corporate Members: 70
Neuroscience society or commi:ee, IBRO
na0onal chapter, research council or similar
- e.g., Argen0nian Society for Research in
Neurosciences, Chilean Neuroscience Society
Academic Members: 12
Na0onal academies of science or similar
- e.g. La0n American Academy of Sciences
(Mexico), Venezuelan Society of Physiological
Sciences

IBRO Organiza9on
Secretariat in Paris
Execu0ve Director Stephanie de la Rochefoucauld
Execu9ve CommiIee
Chair: Sten Grillner (Secretary-General)
Pierre MagistreP (President )
Quen0n Pi:man (Treasurer)
Chairs of the 6 Regional Commi:ees
Co-opted Members

Governing Council
Chair: Pierre MagistreP (president)
Representa0ves of Member Aliated Organiza0ons
Directors of Programmes & Chair of the World Congress Commi:ee
Members of the Execu0ve Commi:ee

IBRO REGIONS

IBRO Regional CommiIees & Chairs

AFRICA: Pierre Luabeya (Democra0c Republic of Congo)

ASIAN/PACIFIC: Keiji Tanaka (Japan)
LATIN AMERICA: Dora Fix Ventura (Brazil)
PAN EUROPEAN: Juan Lerma (Spain)
USA/CANADA: Sharon Juliano (USA)
MIDDLE EAST/NORTHERN AFRICA (Sub-region):

Omar El-Agnef (UAE)

Global Advocacy CommiIee

coordinated by IBRO
Global Advocacy CommiIee formed by SfN, FENS,
IBRO, DANA, ISN, Japanese NS, Australian NS
At the na9onal level only the Na9onal socie9es can
act.
For each region an advocacy workshop
GAC plans to provide seed-money to the dierent
global regions of IBRO

 Global Advocacy Ini9a9ve

2014-15: Kinshasa, Buenos Aires, Mumbai

Neuroscience and society?

The goal must be to inform at all levels of society
Legislators
Funding organisa9ons
Lay public
solid informa9on on important items delivered by
the best available scien9sts credibility. No Hype.

Public funding Cancer and Brain Research

Costs for Cancer and Diseases of the Brain

Disability Adjusted Life Years

Diseases of the nervous system cause 35% of the costs

for healthcare in North-America and Europe.

The BRAIN in
focus for a great
number of
disciplines
Psychiatry
Neurology
Psychology
Linguistics
Geriatrics

Cognitive and Systems

mmNeuroscience
Neurophysiology
Molecular biology
Pharmacology

The Brain not only in disease

How to maintain a healthy brain throughout life
Physical ac9vity, no smoking, diet

Understanding brain func9on from gene to behaviour

understanding ourselves
understanding animal kingdom ethology

Learning and memory - the importance of brain func9on for

educa9on
Develop pharmaceu9cal industry drugs considering
degenera9ve diseases and psychiatric condi9ons
Robo9cs, computers, informa9on processing

 Basic science the unexpected usefulness

-- transistors, CCD cameras, MRI, penicillin,
DOPA therapy against Parkinsons
Clinical care versus investment in science
care versus polio virus vaccine

Translatory from basic mechanisms to

therapy all clinical disciplines

a great challenge for current neuroscience

the interface between
the cellular level and global brain func@on -

?
Behaviour is produced by networks/microcircuits
of interacting nerve cells
gene/molecule - cell - synapse - network behaviour - cognition

How to support??
major breakthroughs are due to individual scien0sts -
through dedicated work and crea0ve recombina0ons
Project grants
Program grants several inves0gators with
complementary exper0se addressing the same problem

Plaaorm building important eg the Human Genome

project, Allen Brain ins0tute, Flagship projectsINCF

Priori0es
US success acer the 2nd world-war funding
but also eec0ve peer review
scholarly selec0on of grants
Problem-oriented rather than purely
descrip0ve
Breakthroughs to be preferred, but it ocen
comes from systema0c incremental research
towards solving a problem

Different Brain initiatives

EU flagship - Human Brain Project

The Obama initiative NIH, NSF, DARPA
Japanese initiative - marmoset
Chinese initiative on the way
Australian initiative on the way?

Current challenge

Excessive accumula0on of neuroscience data at all levels
of analyses
- Diculty to integrate and fundamentally understand
- Extending from genes to cogni0on and diseases
Fragmenta0on and subspecialisa0on many
subdisciplines with very dierent methodology
Many dynamic complex interac0ve processes
Neuroinforma0cs important aid

26-28 Jan 2015

HBP Period 1 Review (Oct 2013 Sep 2014)

Slide 21

GAC - Grants
For specic ac0ons
Prin0ng of advocacy material
Strategy workshops, analyses of specic situa0on
with GAC grants in a given country etc
Organize advocacy ac0ons legislators, media etc
5000?
Prefer not for BAW
Not for transla0ng....

What do we like to achieve??

Awareness of possible strategies for advocacy
for dierent groups
Which organiza0ons are ac0ve, role of APRC
Knowledge of strategies, materials developed
by SfN, FENS or DANA
Experience from other socie0es
Views of dierent funding organiza0ons

Join forces between basic and clinical

neuroscience, and brain-inspired technologies
to argue for all the dierent aspects of
neuroscience

9th IBRO World Congress 2015

7-11 July, Rio de Janeiro, Brazil

IBRO2015.org

IBRO World Congresses

1.Lausanne, Switzerland (1982)
2. Budapest, Hungary (1987)
3. Montral, Canada (1991)
4. Kyoto, Japan (1995)
5. Jerusalem, Israel (1999)
6. Prague, Czech Republic (2003)
7. Melbourne, Australia (2007)
8. Florence, Italy (2011)

IBRO fellowships

Travel grants to mee0ngs,

Short lab visits
Post doc fellowships
Return home fellowships

IBRO Schools

To strengthen research training in each region

100 Schools from 2008-2014

IBRO-FENS Cajal
Advanced Training Programme

Champalimaud Centre and Bordeaux Neurocampus

Neuroscience Journal

Ocial journal of IBRO, 28 issues per year by Elsevier

www.journals.elsevier.com/neuroscience

IBRO-Kemali Founda9on

 IBRO-Kemali Founda9on

IBRO-Kemali Interna9onal Prize

Research in the Field of Basic and Clinical Neuroscience

THANK YOU

IBRO Secretariat
255 rue Saint-Honor
75001 Paris, France
ibrocentral@gmail.com
www.ibro.info

The Brain and society?

The goal must be to inform at all
levels of society
Legislators
Funding organisations
Lay public

solid information on important items

delivered by the best available
scientists credibility. No Hype.

The HUMAN BRAIN is the challenge

of the 21st century

It is an electrochemical machine that enables us to think,

perceive, act and remember that consists of:
100 000 000 000 nervecells
10 000 000 000 000 synapses (contact points)
nervecells form functional modules/networks that
subserve different functions
Energy efficient runs on 30 60 watts
Diseases of the nervous system causes 35% of the
costs for healthcare in North-America and Europe

A large number of subdisciplines deal with brain

func9on with widely dierent techniques

Psychiatry
Neurology
Psychology
Linguis9cs
Systems Neuroscience
Pharmacology
Neurophysiology
Molecular biology

Disease mechanisms
Cogni9on
Emo9ons
Memory and learning
Motor co-ordina9on
Networks
Nerve cells & synapses
Genes

Data bases thus need to extend from genes to

behaviour and disease

Advocacy of Neuroscience in Japan

Chief Vice President, Japan Neuroscience Society

Professor, National Institute for Physiological Sciences
Tadashi Isa

The current situation of neuro-psychiatric disorder

is very serious in Japan
1. The biggest factor that harms the QOL of the Japanese nation is neuro
-psychiatric disorder.
2. 1/40 of the Japanese nation is currently under treatment of neuro-psychiatric
disorder this ratio will further increase in future).
3. The number of people with dimentia is estimated to be 4.6 million
(, which will increase in future because of longevity, while the total
population of Japan, currently 120 million, will decrease).
4. Economical loss by dimentia is estimated to be 1,000,000 million yen/year.
Furthermore, the Japanese peoples average life span is very long, but the number
of children is decreasing (male: 80.21 (world no.4), female: 86.61 (world no.1)).
Currently (in 2015), 25 % of the total population is over 65.

But drug development for neuro-psychiatric disorder is very difficult, presumably

because of the complexity of the target organ, brain.
We may need different strategies from that for cardiovascular disease or liver
dysfunction (drug delivery, animal model, physiological measure).

For this, we need to know more about the brain.

Topics
1. Funding system (s) in Japan
Different Ministries fund neuroscience.
MEXT+JSPS KAKENHI Grant (Bottom-up)
MEXT Flagship (top-down) project (Brain Science Committee)
SRPBS, MINDS
JST
ERATO, CREST, PRESTO, ERATO
Other Ministries (MHLW, MITI, MIC)
2. Japan Neuroscience Society----community of neuroscientists in Japan
3. Japanese Union of Neuroscience Societies
4. Activity for advocacy
Briefing in the Committee of LDP
Master-plan
5. Good side and bad side.
Abbreviations;
MEXT: Ministry of Education, Culture, Sports, Science and Technology
MHLW: Ministry of Health, Labour and Welfare
MITI: Ministry of International Trade and Industry
MIC: Ministry of Internal Affairs and Communications
JSPS: Japan Society for Promotion of Sciences (Agency related to MEXT)
JST:
Japan Science and Technology Agency (Agency related to MEXT)

Funding system(s) in Japan

Different Ministries fund neuroscience.

Strategic
(top-down)

MIC Innovative researches utilizing brain mechanisms

(FY2011-2014, FY2011; 845 million yen)
MITI Early diagnosis of AD by integrating
brain imaging, clinics and IT
(FY2014; 370 million yen)
MLHW Development of Biomarkers and imaging
Technology for depression and schizophrenia
(FY2014; 400 million yen)
MHLW Preclinical AD research
(FY2014; 600 million yen)

MEXT Strategic research programs for brain sciences (SRPBS)

MEXT Brain Mapping by Integrated Neurotechnologies for Disease Studies(Brain/MINDS)
(FY 2015; totally 5,837 million yen)

Development of strategies
for diagnosis,
prevention and therapies

Elucidating the mechanism

of neuro-psychiatric diseases

JST CREST neural circuit analysis

(FY 2009-2016; 19 teams supported for 5 years, 0.5-1 million yen each)
JST CREST Diagnosis and therapies of neuro-psychiatric diseases based on molecular pathology
(FY2007-2014; 14teams supported for 5 years, totally 2.5-5 million yen for each)
JST PRESTO Development and function of neural networks
(FY 2009-2014; supporting 43 young scientists for 3-5 years; totally 50-100 million yen for each)
JST PRESTO Decoding and controlling brain information
(FY 2009-2014; supporting 37 young scientists for 3-5 years; totally 50-100 million yen for each)

Idea-driven
(bottom-up)

MEXT & JSPS Grant-in-Aid for Scientific researches (KAKENHI)

Individual grants; Specially promoted research (no upper limit, 5 years), Type S (totally 200 million yean/5 years)
Young B (totally 5 million yen/2-3 years)
Group grants (Scientific Researches in Innovative Areas); currently totally 19 neuroscience-related groups
(/117 groups from all the scientific fields) are funded (5 years for each, 300 million yean for each group)

Overcoming
neuro-psychiatric diseases

MEXT Strategic researches

of molecular imaging
(FY2014; 250 million yen)

Application of BMI to
Communication technology

Developing
Communication
technology

Application

Basic

Strategic research programs for Brain Sciences (SRPBS)

by MEXT
FY
2008 2009 2010 2011 2012 2013 2014 2015 2016 2017
Topic A (Group leader; M. Kawato (ATR))
Development of BMI

Topic B (individual)
Development of BMI

Topic B (individual)
BMI

Development of creative animal model

(genetic manipulation of primate brain)

Topic D (Group leader; M. Kano (Tokyo))

Development of social brain marker

Topic E (Group leader; H.Mizusawa(Tokyo MD))

Neural functions for life-long health

Topic F (Group leaders; S. Yamawaki, N.Ozaki,

M. Takeda)Elucidating neural mechanism of neuropsychiatric disease and developing therapies

Topic G (Group leader; K.Kaibuchi (Nagoya))

Information infrastructure of neuroscience

BMI technologies Restoration of impaired

body and mental functions by BMI technologies

Development of primate model

Development and distribution of TG
marmosets

Totally 2,630 million yen

Contribution to the Society

Topic C (Group leader; T. Isa (NIPS))

Brain Mapping by Integrated Neurotechnologies for Disease Studies

RIKEN BSI

http://brainminds.jp/en/

How is the decision formed

on the top-down strategic projects?
MEXT, Minister

Brain Science Committee

(neuroscientists (both basic and clinical),
member from pharmaceutical company,
journalist, liberal arts)
+ working groups

Union of Brain Science Associations in Japan

Neuroscience community

Science Council
of Japan
Master Plan

Unique community activity

One of the KAKENHI grant Scientific Researches of Innovative Areas

More than 700 neuroscientists participate

1. Support system (5 items and 13 support centers)
(brain bank, behavioral analysis platform, molecular profiling
large-scaled neural recording technologies, developing animal models etc.)
Upon approval of applications, supports are available.

2. Organizing group meetings twice/year.

Research progress report, poster sessions, discussing on future proposals etc.
Budget; 360 million yen/year

The Japan Neuroscience Society

----community of neuroscientists in Japan
Founded in 1974 by 70 members.
Current number of members; 6000
Headed by Keiji Tanaka as the president

Annual Meetings
About 2000 titles
of presentations
About 3500-4000
participants
All in English
Travel awardees are
invited (30-40 from
all over the world)

Union of Brain Science Associations in Japan

--to form the coherent voice of neuroscientists-Total number of members; 80,000 (22 associations, in August 2014)
Japan Neuroscience Society (6,000)

Japanese Society of Neurology (8,900)

Japanese Society of Child Neurology (3,800)

Physiological Society of Japan (2,800)

Japanese Society of Clinical Neurpphysiology (3,100)

The Japanese Association of

Anatomists (2,500)

Japan Society for Dementia Research (2,400)

The Japanese Society for Neurochemistry

(1,400)

Japan Society of Neurovegetative Research (1,200)

Japanese Neural Network Society

(800)

Japan Neuroendocrine Society (600)

Japanese Society for Neuroimmunology (580)

Neurology
Basic science
Psychology
Japanese Psychological Association
(7,400)

Rehabilitation
Japanese Association of Rehabilitation Medicine
(9,800)
Japanese Society for Neural Repair and
Rehabilitation (460)

Japanese Society of Psychiatry and

Neurology (16,000)

Japanese Society of Sleep Research

(2,700)
Japanese Society Biological
Psychiatry(1,600)
Japanese Society of
Neuropsychopharmacology (1,200)

Japanese Society of Clinical

Neurophychopharmacology (800)

Psychiatry

Neurosurgery
Japan Neurosurgical Society (8,800)

Advocacy by the Union of Brain Science Associations

Chairperson; Hidehiro Mizusawa (Neurology)
Vice chairperson; Shigeo Okabe (Anatomy)
Shigeto Yamawaki (psychiatry)
Executive Committee; Keiji Tanaka (Neuroscience)
Meigen Liu (Rehabilitation)
Nobuto Saito (Neurosurgery)
Tadashi Isa (Physiology)
Toru Nishikawa (Psychiatry)
Future Planning Committee
Chair; Tadashi Isa (Neurophysiology)*
Vice chair; Mitsuo Kawato (Neurocomputation)
Norio Ozaki (Psychiatry)
* Previous chair was Shigeo Okabe.
Proposal
Science Council of Japan

Liberal Democratic Party

Committee for Science &
Technology Innovation
Hearing & briefing (about 1/year)

Good side and bad side (& concerns)

1. Neuroscientist community is more and more integrated
for making coherent voice.
(ref. Union of Brain Science Associations, CBSA)
2. But the policy of the government is becoming
more top-down, application-oriented.
3. From April 2015, a new organization (AMED; Japanese
version of NIH) will start and many of the MEXT
projects (most of the top-downs) will shift to it.

4. Share of Neuroscience papers from Japan is decreasing (!?)

Direction of FY 2015 Korean Government Investment

in Life Health Care Areas
Increased sustainable investment for public
health and new industries creation (Creativ
e Economy)

Maximize R&D performance and efficiency

Strengthen the efficient investment of core technol
ogies
-6-

FY 2015 Government R&D Budget

(Unit :$ In millions)

2014

2015

Total

16,413

17,378

Basic science
Nanotechnology

2,293

2,028

Energy-Environment

2,339

2,350

Aerospace-Life Science

4,348

4,870

Life Science & Healthcare R&D

$ 1,715
(10% of

Machinary-Manufacturing
-Process

1,560

1,589

Information-Electronics

2,400

2,336

Others

3,472

3,814

Total Budget)

Source:- FY 2 0 1 5 B u d g e t b y Ministry of Strategy and Finance

Top of the World Research Intensity : 4% of GDP

(Japan 3.4%, Germany & US, 2.8%)

Investment of Government Departments

in Brain Research for Last 3 Years
(Unit : $ In millions)

Year
Departments

2013

2014

2015

Total

81

100

120

Ministry of Science, ICT and Future Planning

(Government-funded research institution)

60.5

72
(45)

90
(60)

Ministry of Education

Ministry of Trade, Industry and Energy

1.5

Ministry of Health and Welfare

13

16

18

Investment of Government in
Brain Research Areas for Last 3 Years
(Unit: $ In millions)

Year

2013

2014

2015

Total

81

100

120

Brain disorders

40

45

60 (50%)

Basic Neuroscience

15

17

18 (15%)

Neural information &

brain engineering

11

12 (10%)

Cognition

18

27

30 (25%)

Areas

* New Launched Projects :

Brain mapping project of Brain Development, PTSD project,
Pre-diagnostic project for AD prediction, and Internet and game detox project

FY 2015 KBRI Budget

(Unit: $ In millions )

Year
Areas

2014

2015

Total

66

70

Institute Operating Budget

7.3

10.6

Salaries

1.8

2.5

Recurring expenses

0.8

3.5

Intramural R&D

4.6

4.6

Special Budget

6.0

7.9

General expenses

6.0

7.9

- Computer network system

1.3

1.3

- Equipments

3.2

2.7

- Korea Brain Bank

0.7

0.7

- Animal Facility

0.7

3.1

Construction

52.7

51.5

Alzheimers Disease

Death rate of AD
only increases!

Breast
Cancer

Prostate Heart
Cancer Disease

Stroke

HIV

Alzheimers
Disease

Alzheimers Disease
Global Economic Lo
ss
$ 350 billion

World

Economic Impact

Research Fund

2 times higher than

cancer

1/12 of cancer

UK

Korea

UK

R&D Budget
300
250
Direct
Cost

200
Direct
Cost

Indirect
Cost

High income Low income

countries
countries

150
Indirect
Cost

5.7%

100
Dementia
heart
Cancer

Stroke

Dementia
Cancer

heart

Stroke

50
0
Cancer

Vascular
Disorder

Dimentia

We have to try to increase

government R&D Budget
for Brain Research!

KBRI International Network

FY 2014 International Cooperative

Brain Research of Korea

$80,000

KOREA

$80,000

 

$160,000

CNRS

 
$30,000

 

A3

  Foresight

  Program

 
$600,000

 

Securing Core Technology via Strengthening the Strategic Investment

Cognition
Neurooscience

Perception, Attention & Consciousness

Learning, Memory & Language
Emotion, Motivation & Decision-making
Social Cognition

Neural Development & Regeneration

Neural Molecular & Cell Biology
Synaptic Plasticity & Excitation
Regulation of Neuron-Specific Function

Brain Disorders

Brain Engineering
Measurement & Modeling of Brain Structure
Brain-Machine Interface
Brain Function Enhancement Technology

Identification of Disease Mechanism

Drug Development for Brain Disorders

Patent(No.)
Year

Domestic

Articles(No.)
International

Over IF 20

Over IF 10

Total SCI

21

719

45

14

20

532

59

36

12

127

610

49

52

16

10

525

App

Issue

App

Issue

2010

112

32

41

2011

124

80

2012

96

2013

63

Korea Brain Research Institute(KBRI)

We had the opening and completion ceremony o

f the KBRI building on Dec. 4th, 2014.

Vision & Strategy of KBRI

Top 7 World-leading Research Institute
on Convergence Brain Science

Basic Brain Science Research

(Neurobiology & Cognitive
Neuroscience) for Brain
Disease Solution

Medical Brain Science Research

(Brain Diseases Research:
Neurodegenerative and
Neurodevelopmental Disorders)

Convergence Brain
Research:
Brain Mapping
& Brain Engineering

Recruitment plan of KBRI

PI at Assistant or Associate Professor levels should be at

the cutting edge of their field with an established record of
EXCELLENCE in brain research.
We will especially evaluate the record of research within
RECENT 5 YEARS (2009 ~ 2014).

VII. Working Environments of KBRI

Competitive Salary

National Pension,
4 Major Social Insuranc
e

KIST Brain Science Institute

Main Research Areas

Center for Neuroscience
Synaptic mechanisms of cognitive functions
Molecular mechanisms of cognitive functions
Research tool for acquiring, processing, and analyzing brai
n signals
Center for Functional Connectomics
Mapping of functional brain circuit by analyzing mouse mod
els at the synaptic and molecular level
Construction of the brain circuitry database by comparing h
ealthy and diseased brains
Developing therapeutic tools for various neurological disord
ers by identifying molecular mechanisms
Center for Neuro-Medicine
Synthesis and development of leading therapeutic candidat
es
Evaluation of the efficacy of lead compounds in animal mod
el
Development of neuro-imaging probes to diagnose brain di
seases
In silico drug design and assay development
Preclinical evaluation of lead compounds

IBS Institute for Basic Science

Center for Synaptic Brain Dysfunctions
Key Mecanisms of Synaptic Brain Dysfunctions
Neural Mechanism of Dicision making and Episodic momery

Center for Cognition and Sociality

Neural mechanism study on controlling consciousness and unconsciousness

Neural mechanism study on emotion and cognition
Neural mechanism study on sociality
Comprehensive analysis of protein-protein interaction networks
Development of molecular controllers manipulating signaling networks

Center for Neuroscience Imaging Research

Neurophysics, Neurochemistry, and Neural Engineering Group

Computational Neuroscience and Neural Imaging Data Analysis Group
Neurovascular Signaling Group
Primate Systems Neuroscience Group
Human Cognition Mapping Group

Neuroscience Research Institute (NRI)

of Gachon University
Research Team

PET-MRI Fusion
Stroke and Microvascular Imaging
Parkinson's and DBS
Hippocampus and Alzheimer's
fMRI and Cognitive Neuroscience
Animal and Molecular Imaging
RF and GR Coil Engineering
Cyclotron & Radiochemistry

Research Facility
PET-MRI
7.0T MRI
Cyclotron
1.5T MRI, 3.0T MRI & PET/CT
HRRT PET
Micro PET/CT
Ultra Definition Display System

Brain Researchers of Korea

Eight Korean neuroscientists got together during the 1982 meeting of SFN in Minneapolis, Minn
esota and agreed to have annual gatherings of Korean neuroscientists at subsequent meetings of the S
ociety

In 1988, at the Toronto, Canada meeting, bylaws were and the Association was formally founded

There have been well over 230 Korean neuroscientists in attendance at recent annual dinner meet
ings

AKN ANNUAL MEETING REPORT 2014

WASHINGTON, DC

Sponsors 2014

Brain Researchers of Korea

Neuroscience Annual Meeting at SFN Top 5

Thank you
(yhsuh@kbri.re.kr)

Neuroscience Research and

Funding in
Hong Kong SAR / PR China
Ying-Shing Chan
State Key Laboratory of Brain & Cognitive Sciences, University of Hong Kong
Past President, The Hong Kong Society of Neurosciences
Standing Executive Committee Member, Chinese Neuroscience Society

CHINA
Shanghai

Hong Kong SAR

Neuroscience Research Ac5vi5es of universi5es in Hong Kong

- Signal transduc5on in the nervous system

- Forma5on of synapses during development
- Molecular mechanisms underlying neuronal survival
- Structural biology of neuronal signaling complex
- Drug discovery for neurodegenera5ve diseases

- Neuroplas5city
- Parkinsonism

The Chinese University

of Hong Kong

Hong Kong University of

Science and Technology
- Auditory func5on
- Visuo-auditory
interac5on

City University
of Hong Kong

The University
of Hong Kong

- Synap(c plas(city:
Neurotransmi5ers / Neuromodulators
- Neural stem cell: Neurogenesis / iPSCs
- Memory & Alzheimers disease
- Neural regenera(on:
SCI, op(c nerve, peripheral nerve

Hong Kong Grants:

Hong Kong Research Grant Council (RGC)

General Research Fund [USD 150,000 for 3 years]
Funded projects / year: 200 (for Biology & Medicine)

Neuroscience
Collabora5ve Research Fund [USD 500,000 1,000,000 for 3 years] 21 projects
Funded projects / year: 15

Areas of Excellence [USD 4M for 5 years]

Funded projects / round: 3

Theme-based Research Scheme [USD 5M 10M for 5 years]

Funded projects / round: 3
(a) Promo5ng good health

Understanding Disease Mechanisms to Improving Health

Stem Cells and Regenera5ve Medicine

(b) Developing a sustainable environment

Hong Kong Grants:

Hong Kong Research Grant Council (RGC)

Joint Research Schemes

Na5onal Natural Science Founda5on of China / RGC Joint

Research Scheme
[USD 100,000 200,000 for 4 years]
Funded projects / year: 20

Agence Na5onale de la Recherch / RGC Joint Research Scheme

[USD 200,000 300,000 for 4 years]
Funded projects / year: 5

ScoPsh Funding Council / RGC Joint Research Scheme

[USD 20,000 for 1 year]

Hong Kong Grants:

Food and Health Bureau, HK Government

- Health and Medical Research Fund (HMRF) [USD 120,000 for 2 years]

Funded projects / year: 100
1) Infec5ous Diseases / Health Services
2) Advanced Medical Research - Paediatrics, Clinical Gene5cs, etc.
Neuroscience

Industrial & Technology Fund, HK Government [USD 120,000 1M / year]

S.K. Yee Medical Founda5on Grants

1) Establishment of medical services for the poor and sick and the provision of equipment
for such services.
2) Provision of funding to promote biomedical research. [USD 600,000 for 3 years]

The Croucher Founda5on

1) Postdoctoral Research Fellowships - local & overseas. [USD 50,000 / year]

2) Clinical Assistant Professorships [USD 100,000 / yr salary + USD 70,000 seed funding]
3) Advanced Study Ins5tute (5-day workshops) [USD 100,000 @]

The Hong Kong Society of Neurosciences

Founded in 1979
Current President: Wing-Ho YUNG
A corporate member of:

- Interna5onal Brain Research Organiza5on (IBRO)

- Federa5on of Asian-Oceanian Socie5es of Neurosciences (FAONS) -
hosted 4th Congress
- Asia Pacic Society of Neurochemistry (APSN)

Symposia in 2014 Conference:

- Hypoxia
- Learning and memory
- Molecular neuroscience
- Nerve regenera5on
- Neural stem cells
- Neurological disorders
- Neuropep5des
- Neurotrophic factors
- Synap5c plas5city
- Transla5onal neuroscience

Workshop on Biomedical Educa5on

Acupuncture
Astrocyte
Emo5onal disorders (Addic5on, Pain)
Calcium signaling
Cogni5on and fMRI
Computa5onal neuroscience
Nerve injury & repair
Sensory circuitry & behavior
Social behavior: Molecular gene5cs & Circuitry

Peking U
Tsinghua U
Inst Biophysics, CAS
Beijing Normal U

Qingdao U

Cerebellum
Hypothalamus-brainstem interac5on Nanjing U

Xian
4th Military Medical U
Pain

Qingdao
Nanjing

Learning and memory

Degenera5on of basal ganglia

Drug addic5on
Ion channels and receptor
Learning and memory
Neural stem cells
Plas5city: Circuit & Behavior
Sensory systems: Vision, Pain

Inst Neurosci, CAS

Fudan U
Shanghai Jiaotong U
2nd Military Medical U

Shanghai
Hangzhou

Zhejiang U

Kunming
Inst Zoology, CAS

Parkinson disease

Guangzhou

Astrocyte
Circuitry of psychiatric diseases
NMDA receptors

Sun Yat-sen U
Astrocyte
Hippocampal neurogenesis
Pain

PR China Grants:

Na5onal Science Founda5on of China

Regular Research Projects
General Research Projects [USD 0.1 M for 2-4 years] Funding rate: 20%
Key Projects [USD 0.4 M for 2-4 years] Funding rate: 20%
Other funding opportuni5es
- Interna5onal Joint Research Fund
- Key / Major Research Plans

Talent Projects for Young Scien5sts

Young Scien5sts Fund [USD 0.04 M for 2-3 years] Funding rate: 24%
Excellent Young Scien5sts Fund [USD 0.7 M for 2-3 years] Funding rate: 11%
Crea5ve Research Groups [USD >0.5 M]

Research Environment Building Fund

Major Research Equipment & Facili5es [USD 0.5 - 25M] Funded projects / year: 40
Basic Scien5c Research Instrument [USD 0.5 M] Funded projects / year: 50

PR China Grants:

Ministry of Science & Technology

973 Program

Popula5on and Health 17% Projects [USD 90 M]

Resource and Environment

Agriculture
Energy
Informa8on
Materials
Synthesis and Fron8er Science

9% Projects
9% Projects
8% Projects
11% Projects
8% Projects
4% Projects

863 Program

Biology 19% Projects [USD 35 M]

Resource and Environment
12% Projects
Energy
12% Projects
Informa8on
11% Projects
Synthesis 10% Projects
Agriculture 8% Projects
Marine 6% Projects
Materials
6% Projects

(forthcoming)


??

New Program
Chinese NIH equivalent

Source:
MST Annual Report of the State Programs of
Science and Technology Development 2013

The Chinese Neuroscience Society

Founded in 1995
Current President: Shumin DUAN

The Chinese Neuroscience Society

Founded in 1995
Current President: Shumin DUAN

Symposia:

Beijing / September 19 - 22, 2013

- AD, PD
- Auditory circuits & func5on
- Au5sm; Depression; ForgePng
- Computa5onal neuroscience
- Glial cells
- Iron metabolism & neurodegenera5ve disorders
- Tracking of receptors & ion channels
- Motor control & diseases
- Neural stem cell & 5ssue engineering
- Pathological pain
- PET / MRI in human brain
- Repair & regenera5on : CNS and PNS

Neuroscience Educa5on Workshop

The Chinese Neuroscience Society

Founded in 1995
Current President: Shumin DUAN

Chinese Neuroscience Society

will host the 6th FAONS Congress
in Sept. 20-23, 2015
hnp://www.csn.org.cn/en/enindex.asp

Founded in 1996
FAONS Call for Symposia Submission

 Situa'ons of Neuroscience
Funding and Research in Taiwan
Ding-I Yang, Ph.D.
Secretary General-
Taiwan Neuroscience Society
Professor, Ins'tute of Brain Science, Na'onal Yang-
Ming University, Taipei, Taiwan

TAIWAN: Where?
China

TAIWAN

Philippines

IBRO-APRC Global Advocacy/2014-Feb-03

TAIWAN: basic informa'on

Republic of
China
Area:
36,193 km2
Popula'on:
23.4 million
Ocial
language:
mandarin
Capital: Taipei

Taipei

Taipei 101 (508 m)

Na'onal Palace Museum

IBRO-APRC Global Advocacy/2014-Feb-03

Jadeite Cabbage

Outline
1. Es'mated numbers of PIs and publica'ons in neuroscience and
brain research since 2012
2. Major funding agencies in Taiwan
1. Ministry of Science and Technology (MOST)
2. Ministry of Educa'on (MOE)
3. Na'onal Health and Research Ins'tute (NHRI)
4. Private founda'ons
5. Hospitals
3. Funding situa'ons in the neuroscience- and brain-related
research ins'tutes in Taiwan
4. Crises and challenges in current situa'ons for neuroscience
research in Taiwan
IBRO-APRC Global Advocacy/2014-Feb-03

1. Researchers in neuroscience and

brain science
Facul'es in the research ins'tutes related to
neuroscience and brain science: 11 ins'tutes, 82
facul'es in total.
Facul'es in neuroscience/brain research who are in
other ins'tu'ons like pharmacology, physiology,
toxicology, biochemistry, molecular biology, cellular
biology, and anatomy, etc.
Taiwan Neuroscience Society: 158 regular
members, 140 student members, 318 in total.
Clinical neurologists who are ac've in research.
IBRO-APRC Global Advocacy/2014-Feb-03

Number of Published Articles

1. Publica'ons during 2012-2015

Total: 2690+850=3540

1000

Brain-related articles
Neuron-related articles

800
600
400
200
0

* Up to January 30th, 2015

2012

2013

2014

2015*

Searched from PubMed

IBRO-APRC Global Advocacy/2014-Feb-03

2. Funding resources in Taiwan

1. Ministry of Science and Technology (MOST)
2. Ministry of Educa'on (MOE)
3. Na'onal Health and Research Ins'tute
(NHRI)
4. Private founda'ons
5. Hospitals (especially those aliated with
medical schools)

IBRO-APRC Global Advocacy/2014-Feb-03

2.1. Ministry of Science and

Technology
MOST, formally the Na'onal Science Council (NSC),
is the main government funding agency for research
in Taiwan
Department of Life Sciences in MOST is the division
to which most of the researchers in neuroscience
and brain science submit their grant proposals.
The only funding opportunity specic for
neuroscience research is Projects for the
Promo'on of Neuroscience Research (2008-2017).
IBRO-APRC Global Advocacy/2014-Feb-03

MOST: Projects for the Promo'on of

Neuroscience Research-I

(*104 USD)

300
250

250

271

301

200
150
100
50
0

201

201

201

60
(*104 USD/project)

350

6/32

50

18.8%

40
30

14/69

20
10
0

IBRO-APRC Global Advocacy/2014-Feb-03

20.3%

38/149
25.5%

2
3
4
201
201
201
38=30+8 (2 program projects)
14=11+3 (1 program project)
9

MOST: Projects in Neurology-II

(*104 USD)

300
250

257

293
244

200
150
100
50
0

201

3
201

(*104 USD/project)

350

6
5

45/107
45/106
42.5%

42.1%

42/102
41.2%

4
3
2
1
0

2
3
4
201
201
201
45=41+4 (1 program project)
45=45+0 (No program project)
IBRO-APRC Global Advocacy/2014-Feb-03 42=42+0 (No program project)
10

201

MOST: Projects in Neurosurgery-III

(*104 USD)

168

184

150
100
50
0

201

3
201

4
201

8
(*104 USD/project)

190

200

25/59
42.4%

28/66
34/75

42.4%

45.3%

4
2
0

2
201

3
201

4
201

No program project
IBRO-APRC Global Advocacy/2014-Feb-03

11

MOST: Projects in Psychiatry-IV

293
257

200
(*104 USD)

244

150
100
50
0
2

012

3
201

014

7
(*104 USD/project)

250

35/85 35/84

38/91

41.2%

41.7%

41.8%

4
3
2
1
0

2
201

3
201

4
201

No program project
12
IBRO-APRC Global Advocacy/2014-Feb-03

MOST: I+II+III+VI

1200
800

874

984

961

600
400
200
0

201

201

4
201

(*104 USD/project)

(*104 USD)

1000

10

7.69

8
6

8.66

5.99

4
2
0

IBRO-APRC Global Advocacy/2014-Feb-03

201

201

201

13

Neuroscience budget in MOST

The 2013 annual budget for MOST is approximately
42.26 billion NTD, corresponding to 1.41 billion
USD.
This gure represents around 0.291% of our GDP
(gross domes'c product; 484.7 billion USD in 2013).
The 9.84-million gure in 2013 represents 0.698% of
the total MOST annual budget.
This is underes'mated value as funding from other
categories (such as biochemistry) is not included.
IBRO-APRC Global Advocacy/2014-Feb-03

14

Budget for a Typical MOST Grant

This is a 3-year grant
supported by MOST, the 1st
year budget is 43333 USD.
The pie chart demonstrates
the distribu'on of various
costs for this project in USD.
The consumables and
reagents may also used to
hire a technician, cos'ng
approximately 17000 USD/
year.
IBRO-APRC Global Advocacy/2014-Feb-03

Administrative cost: 4683

Travel: 3333
Personnel: 12800
Consumables and reagents: 22517

29.54%

7.69%
10.81%

51.96%

15

2.2 Ministry of Educa'on:

the 5-Y/5-B Plan
5-Year/5-Billion NTD (1.6 billions USD)
The rst term (2006-2010): Aim for Top University and Research
Center Plan
The second term (2011-2016): Aim for the Top University Plan

Brain/Neuroscience-related research: Na'onal Taiwan

University (Neuroscience and cogni've science; I); Na'onal
Yang-Ming University (Brain science; I and II); Taipei Medical
University (Stroke Research Center; I); Na'onal Tsing-Hua
University (Brain science; II)
Brain Research Center in Na'onal Yang-Ming University
each year received <1 million USD research funding,
individual PI may receive 10000-20000 USD research
funding each year. IBRO-APRC

Global Advocacy/2014-Feb-03
16

2.3-5. Other Funding Resources

3. Na'onal Health and Research Ins'tute (NHRI)
4. Private founda'ons
Taiwan Founda'on for Rare Disorders
Yen Tjing Ling Medial Founda'on

5. Hospitals (especially those aliated with medical

schools)
Department of Health in Taipei City Government
Cheng Hsin General Hospital
Taipei Veterans General Hospital
IBRO-APRC Global Advocacy/2014-Feb-03

17

3. Funding situa'on in individual

research ins'tute
Depending on the number of faculty, as well as
their research performance, one ins'tute may
receive approximately 44000-1380000 USD from
MOST each year during 2012-now.
Each PI may receive 27000-138000 USD for each
project of 1-4 years.
Funding from other resources are not included.

IBRO-APRC Global Advocacy/2014-Feb-03

18

Na'onal Yang-Ming University

Ins'tute of Brain Science
70

(*104 USD/faculty)

(*104 USD)

60
50
40
30
20
10
0

013 3/2014 4/2015 5/2016

2
/
2
201 201 201 201

Faculty number: 9

5
4
3
2
1
0

013 3/2014 4/2015 5/2016

2
/
2
201 201 201 201

IBRO-APRC Global Advocacy/2014-Feb-03

19

4. Crises and Challenges

Less young men are willing to devote themselves
into basic research, including neuroscience and
brain science, which is in part due to the lack of
opportuni'es for permanent job posi'ons in either
academy or industry.
Low birth rate leading to less undergraduate and
graduate students
Shortage in funding opportuni'es and resources.
Basic research versus clinical applica'on.
IBRO-APRC Global Advocacy/2014-Feb-03

20

Acknowledgements
Dr. Shaw-Jeng Tsai; Director, Department of
Life Sciences, Ministry of Science and
Technology, Taiwan
Dr. Ching Cheng; Program Manager for
Promo'on of Neuroscience Research,
Department of Life Sciences, Minister of
Science and Technology, Taiwan

IBRO-APRC Global Advocacy/2014-Feb-03

21

International Brain Research Organization

Tata Institute of Fundamental Research

Bringing Neuroscience to the World

(Deemed University)

APRC member society representative

(Malaysia)
Dr. Pike-See Cheah (Pixie)
Universiti Putra Malaysia
Chair (Basic Neuroscience Chapter Malaysian Society of Neurosciences)
Vice president (Malaysian Society of Neurosciences)
Council member (Asia Pacific Society for Neurochemistry)

1
1

Universi(es in Malaysia

21

Public =
(APEX U = 1)
(RU = 4)

Private Universi(es,
Universi(es colleges, Malaysian
campuses of foreign universi(es
=

82

The Neuroscience Research is recognised as one

of the priority niche areas in some universities
of Malaysia.

Situa(on of support and funding

to brain science/neuroscience in
Malaysia

Research Funding in Malaysia

MP is a comprehensive blueprint prepared by the
Economic Planning unit (EPU) of the PMs Department
& the Finance Ministry of Malaysia

Research Funding in Malaysia

In year 2011, 10th Malaysia Plan

allocated RM 600 millions /
US $ 170 millions as research grant
for public ins(tu(ons of higher
learning.
- Educa(on and Higher Learning Minister
II , Datuk Seri Idros Jusoh

Tenth Malaysia Plan (MP10)

2011-2015

Tenth Malaysia Plan (MP10)

2011-2015
MOSTI Ministry of Science, Technology & Innova(on

Research Funding in Malaysia

~US $148

~US $75

~US $287

~US $89

~US $434

~US $163

The por(on of research funding on NEUROSCIENCE

9
is NA MOSTI, Malaysia (data obtained on 30 Nov. 2014)
th

Situa(on of support and funding

to brain science/neuroscience in
Malaysia (RU, APEX)

10

Research Funding in Malaysia

In 2011, a total RM20 million has been given to seven
Centres of Excellence (CoEs) to spur them to achieve the
status of Higher Ins(tu(on Centres of Excellence
(HICoEs).
1. Ins(tute of Oceanography, UMT
2. Photonics Research Centre, UM
3. Environment and Development Ins(tute, UKM
4. The Malay World and Civilisa(on Ins(tute, UKM
5. Centre of Excellence for Malaysian Technical University
Network (CoE MTUN)
6. Centre for Research in Nanotechnology and Catalysis, UM

7. Neuroscience Service and Research Centre, USM

11

Mission : P3Neuro aims to welcoming the

Government's call to generate insightful and highly
potential human resources for science
Vision : P3Neuro offers eight main excellence
services to local, regional and international levels.
12

* Clinical Neuroscience

* Social Neuroscience

* Fundamental Neuroscience

* Neuro-industry & community

* Neuroeducation (innovation)

* Neuroinformatics,
computering neuroscience

* Neuro-literatures, public research

* Neuro-aesthetics (music, media)

* Cognitive Neuroscience

* Neuroimaging

https://www.facebook.com/P3NeuroUSM

* Biomedical
Neuroengineering

13

Large scale brain mapping

14

Public Universi(es

Neuroscience
research program
Brain & Neuroscience (BNS)
Community of Research (CoRe)

Neuroscience Research
Institute (coming soon)

15

Private Universi(es

16

Funding opportunity
Funding
body
MOSTI

Grant name
E-science fund
FRGS (Fundamental Research

Neuroscience
field (specify or not?)
YES

Grant Scheme)

MOE
ERGS (Exploratory Research
(Ministry of Grant Scheme)
Education) LRGS (Long-term Research
Grant Scheme)

PRGS (Prototype Research

Grant Scheme)

RU (Research Various types

University)

17

MOSTI Malaysia

Ministry of Science, Technology & Innova(on

Malaysian Research and Development Classica(on System - 6th Edi(on

FOR (Field of Research)
Category

Group

Area

Division 1
Natural Sciences

Systems
Biology

Systems Neuroscience

Division 5
Medical and
Health Sciences

Neurosciences

Auditory Neuroscience, Autonomic Nervous System,

Cell Receptors , Cellular Nervous System,
Central Nervous System, Cerebral Palsy,
Cerebral Vascular Disorder, Degenerative Diseases,
Epilepsy, Migraine,
Molecular Characterization, Neuropsychiatry,
Peripheral Nervous System, Psychogeriatrics
Sensory Systems, Sleep Disorders,
Trauma Inflammation (Including
Mechanism of Tissue Damage;
Head Injury)
Other Neurosciences n.e.c.

Biomedical
Science

Behavioural Neuroscience

18

Funding opportunity
Funding
body
MOSTI

Grant name
E-science fund
FRGS (Fundamental Research
Grant Scheme)

MOE
ERGS (Exploratory Research
(Ministry of Grant Scheme)
Education) LRGS (Long-term Research

Neuroscience
field (specify or not?)
YES
NO
NO

Grant Scheme)

PRGS (Prototype Research

Grant Scheme)

RU (Research Various types

University)

19

Funding opportunity

20

Funding opportunity
Funding
body
MOSTI

Grant name
E-science fund
FRGS (Fundamental Research
Grant Scheme)

MOE
ERGS (Exploratory Research
(Ministry of Grant Scheme)
Education) LRGS (Long-term Research
Grant Scheme)

Neuroscience
field (specify or not?)
YES
NO
NO
NO

PRGS (Prototype Research

Grant Scheme)

RU (Research Various types

University)

21

Funding opportunity

22

Funding opportunity
Funding
body
MOSTI

Grant name
E-science fund
FRGS (Fundamental Research
Grant Scheme)

MOE
ERGS (Exploratory Research
(Ministry of Grant Scheme)
Education) LRGS (Long-term Research

Neuroscience
field (specify or not?)
YES
NO
NO
NO

Grant Scheme)

PRGS (Prototype Research

if applicable

Grant Scheme)

RU (Research Various types

University)

23

Funding opportunity

24

Funding opportunity

NO local grants specially dedicate to the elds of

fundamental neurosciences.
For MAJOR grant applica(on, there is ligle or no room
for the neurosciences elds as we know exist in
developed countries.

25

Eorts that the community has

made in Malaysia for promo(on
of funding to brain science/
neuroscience (successful and
unsuccessful results)

26

Funding from community

Limited funding from Malaysian community dedicated to
the research of fundamental neurosciences (unlike
cancer research) .

27

Eorts for promo(on of

funding to brain science/
neuroscience
To gather together all professionals and allied health professionals in
related fields to encourage activities promoting greater interest in the
ever-widening field of Neurosciences. www.neuro.org.my
To foster fundamental and comparative scientific research
contributing to an understanding of the nervous system of
higher brain functions, biological basis of behaviour and its
disorders.. hCp://www.med.monash.edu.my/research/priori(es/
brims/neuromalaysia-society

28

Eorts for promo(on of

funding to brain science/
neuroscience

Malaysian Neuroinformatic Node & Collaborative Projects Workshop

29
5-year roadmap of projects. Oct. 2014.

Support from government

MyCEB (Malaysia Conven(on & Exhibi(on Bureau)
A non-prot organiza(on established by the Ministry of Tourism, Malaysia.

2016

13th Meeting of the APSN, Kuala Lumpur , Malaysia.

250-300

30

13th Meeting of APSN 2016

Kuala Lumpur, Malaysia
27th-30th August 2016
APSN Neuroscience School 2016,
Kuala Lumpur , Malaysia.
22nd 26th August 2016

Presented by

Supported by

31

Support from government

32

Ideas , for interna(onal

coopera(on in advocacy of brain
science/ neuroscience to policy
makers and public

33

Strategy : Malaysian researchers collaborate with

overseas collaborators via a win-win collabora(on to
work on the compounds isolated from plants or other
natural products in Malaysia to facilitate the
iden(ca(on of novel drugs in trea(ng neurological
disorders.

34

Strategy : Similar massive ini(a(ve like the Brain

Research Through Advancing Innova(ve
Neurotechnologies (BRAIN) in United States.

35

Materials and / or thoughts that

will help other par(cipants to
think about promo(on of funding
to brain science/neuroscience
research and related
interna(onal coopera(on
36

Bigger science funding is absolutely crucial

Malaysias funding for scientific research
compared to the countrys GDP is hugely
imbalanced.

37

Research and development expenditure

(% of GDP, 2014)
Country

% of GDP

South Korea

3.60

Japan

3.40

United States

2.80

Singapore

2.70

Taiwan

2.40

Australia

2.30

China

2.00

New Zealand

1.27

India

0.90

12

Malaysia

0.80
38

Interdisciplinary Research
To attract more attention of government and
public to capitalize/invest on the brain, there is a
need to create symbiotic development of
neuroscience in business & marketing is a
potential approach.

39

Brain in Business (B in B)
To promote an exotic union of science and the
arts, focus on the economics of neuroscience
integrated neuroscience:
vNeuroeconomics
vNeuromarketing
vNeurogovernance
(by Ahmad, ZA., 2010)

40

Does Neuroscience stand for a chance for

the funding opportunity below?
Effort of MOSTI, Malaysia with regard to funding
as well as other initiative :
v Additional allocation of RM 50 million (~US
$13.8 million) for Strengthen Technology
Commercialization Platform Programme
v RM 100 million to fund high impact R,D & C
programme
41

Do you agree ?
The new brain THINKS. It processes rational data.
The middle brain FEELS. It processes emotions and gut feelings.
The old brain DECIDES. It takes into account the input from the
other 2 brains, but the old brain is he actual trigger of decision.
by Renvoise & Morin, Neuromarketing, 2007.

42

THANK you!

43

43

NEUROSCIENCE
COMMUNITY AND
RESEARCH IN SINGAPORE
S T Dheen
President, Singapore Neuroscience Association
Asst Dean (Ph D Program)
Chairman, NUS Medicne Graduate Program Committee,
Yong Loo Lin School of Medicine.
National University of Singapore
03 February 2015

SINGAPORE NEUROSCIENCE
ASSOCIATION (SNA):
AN INTRODUCTION

CELEBRATING
Founded by
Professor Laurence Garey
on
29 January 1988

OF JOURNEY

Our Mission
To encourage dialogue and collaborations between
neuroscientists in Singapore

PAST PRESIDENTS

Prof. Laurence
Garey
Prof. Tan Choon
Kim
Prof. Ling EngAng
Prof. Samuel Tay

PRESENT COMMITTEE
President

A/P S. T. Dheen

Vice President

Hon Secretary

A/P Ong Wei Yi

Members

A/P Samuel S.W. Tay A/P Charanjit Kaur

A/P Gavin Dawe

A/P Liang Fengyi

Hon Treasurer

Dr. Karthik Harve

Ms Shweta Jadhav

PROMOTE NEUROSCIENCE
RESEARCH IN SINGAPORE
Bring basic scientists & clinicians
together
Train young researchers
Public awareness

BRING BASIC SCIENTISTS

AND CLINICIANS
TOGETHER

COLLABORATIONS BETWEEN
CLINICIANS AND BASIC SCIENTISTS

Neuroscience seminars to forge

collaborations between clinicians
and basic scientists

Dr. Wai T Wong

Prof. Jeffory Raisman

Prof. Ling Eng-Ang Prof. Ranga Krishnan

Prof. Bin Hu Dr.. John W McDonald III

ORGANIZE NEUROSCIENCE CONFERENCES

L O C A L LY A N D I N T E R NA T I O NA L LY

10

11

TRAIN YOUNG
NEUROSCIENTISTS IN
NEUROSCIENCE EDUCATION
AND RESEARCH

FINANCIAL SUPPORT TO STUDENTS AND

P O S T- D O C S F O R A T T E N D I N G
INTERNATIONAL CONFERENCES

12

IBRO-APRC NEUROSCIENCE
SCHOOL 2015
Motivate young aspiring neuroscientists
from Singapore and the Asia-Pacific region
Offer them an in-depth understanding of the
functioning of the nervous system in health
and disease
Demonstrate advanced neuroscience
techniques to enable them in performing
competitive neuroscience research

13

14

PROMOTE PUBLIC AWARENESS

ABOUT NEUROSCIENCE
EDUCATION & RESEARCH

Singapore Brain Bee Challenge

A not-for-profit neuroscience competition for high school
students to motivate students to learn about the brain

Singapore Brain Bee Challenge 2012

Singapore Brain Bee Challenge 2013

15

PRESS RELEASE: BRAIN BEE

CHALLENGE

16

U P DA T E S O N R E C E N T H A P P E N I N G S
IN BRAIN RESEARCH IN SINGAPORE

Issue 1

Issue 2

Issue 3

Issue 4

Neuroscience.org.sg

17

18

NEUROSCIENCE RESEARCH
AREAS & INSTITUTES IN
SINGAPORE

N E U RO S C I E N C E R E S E A RC H
IN SINGAPORE
By research topic
v Cognitive Neuroscience
v Psychophysics
v Systems Neuroscience
v Molecular Neuroscience

By institution
v NNI
v SINAPSE
v Duke-NUS
v NUS
v NTU

v Computational Neuroscience

19

FUNDING
funded by a number of funding agencies/ institutes

20

R E C E N T LY F U N D E D N E U R O S C I E N C E
PROJECTS BY NMRC
v Alzheimers disease
v Spinal Muscular Atrophy
v Chronic pain
v Neuropathic pain
v Neural crest-derived tumors
v Diabetic peripheral neuropathy

21

Tan Tock Seng Hospital

Singapore General Hospital (SGH)

Areas of Research/Programs

Stroke

Dementia
Movement Disorders
Neuro-genetics
Neuro-Oncology (includes stem cell)
Surgical Navigation (includes robotics)

22

National University Hospital

(NUH)
SINAPSE focuses on Neurotechnologies for basic science, clinical application
and commercialization.
The Institute brings together basic scientists, computational scientists,
experimentalists and clinicians, engineers, innovators and entrepreneurs for
innovation of medical devices for brain disorders .

Areas of Research/Programs

Neurodevices

Systems Neurophysiology
Neural Protheses
Cognitive Engineering
Robotics Rehabilitation

23

Singapore General Hospital

(SGH)

Areas of Research/Programs
vNeuroscience and Behavioral Disorders (NBD)
Parkinsons disease
Cognitive disorders
Developmental disorders
Schizophrenia
Diseases of the neural retina

24

National University Hospital

(NUH)

Areas of Research/Programs
v Synaptic plasticity, learning and memory and cognition
v Epigenetics in neurodevelopment, neuroinflammation, stroke, glioma,
and Alzheimers disease
v Translating basic neurobiological findings to clinically relevant questions

25

Areas of Research/Programs
Molecular and cellular neuroscience using Optogenetics
Translational molecular neuroimaging, testing and validation of novel
molecular imaging biomarkers and humanised animal disease models
for neurological and psychiatric diseases

26

THANK YOU

27

Research Advocacy :
Lessons from the Australian Experience

John A.P. Rostas

President, Australasian Neuroscience Society 2012-2014

University of Newcastle, Australia

JAP Rostas, 2015

Can we idenKfy successful strategies for advocacy

that will work across mulKple societal systems?
Australia
1 country
1 government
23 million people

Asia-Pacic Region
many countries
many governments
> 4 billion people

JAP Rostas, 2015

Burden of Disease

Mental and neurological disorders account for :

43% of disability
25% of combined mortality and disability
~20% of government health research funding

JAP Rostas, 2015

Australias expenditure on research and development in

health is similar to the average of the OECD countries
Government Spending on Health R&D
as Percentage of Health Budget

Government Spending on Health R&D

per capita populaKon ($)
USA
Australia
United kingdom
Canada
Denmark
France
Korea
New Zealand
Germany
Japan
Hungary

USA
Australia
Korea
United Kingdom
Canada
Hungary
Denmark
France
New Zealand
Japan
Germany
0

20

40

60

80

100

120

0.5

1.5

2.5

3.5

JAP Rostas, 2014

Flow of Research Funding

Philanthropy

Government

Industry

Research
Community

~70% of research funding in Australia comes from government (~80% in NZ)

Research funding from philanthropy and industry is growing

JAP Rostas, 2015

Capacity to Inuence Research Funding Through Advocacy

Strength:
Seeking funding for others, represent community popular support
Weakness:
MulKple (oLen narrow) areas of focus,
need organisaKon, technical experKse, high prole champions

Strength:
Can provide co-funding, investment
Weakness:
Narrow focus of interest

Philanthropy

Strength:
Technical experKse, authority, presKge
Weakness:
Self interested (need public support, or high prole champion)
MulKple interests/prioriKes (need coordinaKng organisaKons)

General Public

Government

Industry

Research
Community

JAP Rostas, 2015

Major focus

Secondary Focus

Minor Focus

OrganisaKons

Target for Advocacy and/or Advice

EducaKon &
Research
Community

Industry &
Commercial
Investment

Government
General Public Philanthropy
Policy

ANZ AssociaKon for Advancement of

Science (ANZAAS)
Academic SocieKes
Australian Academy of Sciences (AAS)
Australian Society for Medical
Research ANZAAS
(ASMR) - established 1888

- focus on public appreciaKon of the importance of science; educaKon in schools

Disease L obby Groups and PaKent

Support Groups

Academic SocieKes - most modern scienKc socieKes established aLer 1950

Science and Technology
Australia - focus on advancement of research and teaching
(STA)

AAS
- established 1954
Chief ScienKst
- focus on recogniKon of scienKc excellence; internaKonal collaboraKon;
public educaKon; government policy
Research Australia (RA)

JAP Rostas, 2015

Major focus

Secondary Focus

Minor Focus

OrganisaKons

Target for Advocacy and/or Advice

EducaKon &
Research
Community

Industry &
Commercial
Investment

Government
General Public Philanthropy
Policy

ANZ AssociaKon for Advancement of

Science (ANZAAS)
Academic SocieKes
Australian Academy of Sciences (AAS)
Australian Society for Medical
Research (ASMR)
Disease Lobby Groups and PaKent
Support Groups
Science and Technology Australia
(STA)
ASMR - established 1961

- focus on poliKcal, scienKc and public advocacy for the health

and medical research sector
Support Groups - most formed since 1960s
Research Australia (RA)

- focus on fundraising and policy for beWer paKent care
Chief ScienKst

JAP Rostas, 2015

Major focus

Secondary Focus

Minor Focus

OrganisaKons

Target for Advocacy and/or Advice

EducaKon &
Research
Community

Industry &
Commercial
Investment

Government
General Public Philanthropy
Policy

ANZ AssociaKon for Advancement of

Science (ANZAAS)
Academic SocieKes
Australian Academy of Sciences (AAS)
Australian Society for Medical
Research (ASMR)
Disease Lobby Groups and PaKent
Support Groups
Science and Technology Australia
(STA)
Chief ScienKst

STA Australia
- established
1985
Research
(RA)

- focus on promoKng science & technology policy to government, industry & community
Chief ScienKst
- established 1989

- focus on advice to government on science and technology
JAP Rostas, 2015

Major focus

Secondary Focus

Minor Focus

Target for Advocacy and/or Advice

OrganisaKons

EducaKon &
Research
Community

Industry &
Commercial
Investment

Government
General Public Philanthropy
Policy

ANZ AssociaKon for Advancement of

Science (ANZAAS)
Academic SocieKes
Australian Academy of Sciences (AAS)
Australian Society for Medical
Research (ASMR)
Disease Lobby Groups and PaKent
Support Groups
Science and Technology Australia
(STA)
Chief ScienKst
Research Australia (RA)

RA
Australia

- established 2000
- focus on making health and medical research a higher priority for
JAP Rostas, 2015

Strategies for Successful Advocacy

1. Speak with one voice

One organisaKon (or a few) represenKng an enKre area of

research with reasoned arguments supported by evidence
MulKple organisaKons advocaKng for dierent things are usually
ignored

2. Engage with the community

Engage with passionate volunteers and build interest and

understanding through public events and students
Explain the benets and relevance of research
Build foundaKon for strong public support when needed
CulKvate the natural interest and curiosity of students
recruiKng interest and support from the next generaKon

JAP Rostas, 2015

Strategies for Successful Advocacy

3. Know your audience (e.g. government, industry,
philanthropy, community, journalists)

What is important to them? Frame your arguments in their language.

What do they need from you if they want to help you?
Present informaKon at the right Kme to t their deadlines
Who should present your arguments?

Eminent senior person?

EnthusiasKc young researcher?

Individual person, small group or large delegaKon?

Train researchers especially young researchers for advocacy

4. Independent, authoritaKve data

Commissioned from independent consultancy services

Provided by the Chief ScienKst or independent academy
Peer reviewed, published data
JAP Rostas, 2015

Major focus

Secondary Focus

Minor Focus

OrganisaKons

Target for Advocacy and/or Advice

EducaKon &
Research
Community

Industry &
Commercial
Investment

Government
General Public Philanthropy
Policy

ANZ AssociaKon for Advancement of

Science (ANZAAS)
Academic SocieKes
Australian Academy of Sciences (AAS)
Australian Society for Medical
Research (ASMR)
Disease Lobby Groups and PaKent
Support Groups
Science and Technology Australia
(STA)
Chief ScienKst
Research Australia (RA)

JAP Rostas, 2015

Science Meets Parliament

A Major Event Organised by STA

Annual Event
2 Days in Parliament House (Canberra)
200 scienKsts
>120 parliamentarians (government and opposiKon)

Day 1
InformaKon/training by parliamentarians, staers, journalists, lobbyists in:
How to successfully engage poliKcians, journalists
Requirements of government policy making
Formal dinner at Parliament Houses Great Hall with guest speakers.

Day 2
More than 100 formal meeKngs between scienKsts and Parliamentarians
Usually 2-3 scienKsts speaking with an individual MP.
JAP Rostas, 2014

Keys to Successful Advocacy

1. Speak with one voice
2. Engage with the community
3. Know your audience their needs and interests
4. Use independent, authoritaKve data
5. Provide training in advocacy for researchers
JAP Rostas, 2014

Over the years SmP has received strong support from many sponsors
including:
- Department of Industry, InnovaKon, Science, Research & TerKary
EducaKon
- CSIRO
- Australian Research Council (ARC)
- NaKonal Health and Medical Research Council (NHMRC)
- Australian Academy of Science (AAS)
- Academy of Technological Sciences and Engineering (ATSE)
- Australian Nuclear Science and Technology OrganisaKon (ANSTO)
- Australian Technology Network (ATN)
- Defence Science and Technology OrganisaKon (DSTO)
- Group of Eight UniversiKes (Go8)
- Australian InsKtute of Marine Science (AIMS)
- NaKonal TerKary EducaKon Union (NTEU)
- Australian Synchrotron
- Bio21 Cluster
- Taylor and Francis
- Research Australia
- CSL
- Charles Darwin University
- LaTrobe University
- Australian Astronomical Observatory
- NaKonal Climate Change AdaptaKon Research facility
- ANU Colleges of Science

Neuroscience in India

IBRO-APRC Global advocacy workshop

TIFR, Mumbai

Neuroscience research, funding,

and direcFons in India

Upi Bhalla NCBS Bangalore

Research

InsFtuFons
SocieFes
TranslaFonal and biomedical environment
Academic environment
Regulatory environment
InternaFonal Fes

InsFtuFons

NBRC:

NaFonal Brain Research Centre

1997
Dedicated
neuro insQ
Systems
Human
Imaging
(20)

IISER Pune
2006
General
Science + UG
teaching
Physiology
ComputaFonal
Birds, ies, sh
(6)
6

TIFR Mumbai
1945
All sciences
including
general bio
Dev Neuro
Rodents,
worms,
ies
Cell physiol
Stress
(4)
7

IISc: CNS, MBU, Math, Physics

1909

All Sciences
Primates
AD
Dev neuro
Systems
Comp. neuro
(12+8)
Upcoming
Aging centre
8

NIMHANS:

NaFonal InsFtute for Mental Health and

NeuroSciences: 1870, 1974
Complete
Medical + Basic
Unparalleled
paFent pool
All neurology-
related
acFviFes
Brain Bank
Animal models
~200
9

NCBS/TIFR
1992
General
biology
Systems
neuro
ComputaFon
OlfacFon +
Chem ecology
Rodents,
insects, sh
10
~10

Research

InsFtuFons
SocieFes
TranslaFonal and biomedical environment
Academic environment
Regulatory environment
InternaFonal Fes

11

Research: socieFes
Indian Academy of Neurosciences (1982)
Holds annual meeFng, dierent venues
Over 900 members
Both basic and medical neuro
Travel awards
Publishes Annals of Neurosciences

Indian NaFonal Node for NeuroinformaFcs

INCF member
Holds annual internaFonal workshop
Holds annual short course
12

INNNI members around India

13

Research:

TranslaFonal and biomedical environment

Dicult to wear both
hats
No tradiFon of MD-PhDs
Clinical pressures
Emerging schemes

A few research hospitals

NIMHANS, AIIMS, CMC,
SCTIMST, St. Johns
Remarkable cohorts
Beginning involvement in
naFonal and
internaFonal consorFa
14

Research: Academic environment

Dominated by a few research insFtutes, liQle university
research
Strong medically-based and molecular tradiFons
Anatomy, pharmacology, imaging, neurochem

Other areas sFll small

Few in systems ( more than half in Bangalore)

Few in Dev neuro
Remarkably, few in computaFonal neuro

Winds of change

Many young scienFsts looking to return

Shie from inbred hiring
Stringent tenure policies emerging
Strong summer student and internship tradiFon
Good scholarships at student/postdoc level
15

PublicaFon growth

16

Research: Regulatory environment

IAEC, CPCSEA,
IBSC, IC-SCRT,
NAC-SCRT,
HMSC
17

Research

InsFtuFons
SocieFes
TranslaFonal and biomedical environment
Academic environment
Regulatory environment
InternaFonal Fes

18

Funding
Government
Private
Biography of a grant

19

Funding: Government+

225M$, ~5%

1.6B$

550M$

20

Grants are clustered

21

Government funding prole

5-year plan structure
Unclear about future shape

Financial year rhythm

Ministry of nance role
Disconnect between basic and applied
Big science vs. individual invesFgator-driven

Falling share of GDP

22

Neuroscience-specic schemes
DBT Task force on Neuroscience: 2009 on.

DST CogniFve Sciences IniFaFve

~15 million USD
23

IniFaFves: mixed success

Neuro TF: From 12 to >150 proposals/year

Success rate seemed to seQle at ~30%

Approval cycle fast, funds release lagged. ~100K USD

Indian NaFonal Node for NeuroinformaFcs

Annual meeFng
Annual course

Medical and neuroinformaFcs training iniFaFves

Mixed

CAMP@Bangalore summer course on ComputaFonal

Approaches to Memory and PlasFcity
InternaFonal Fes
Brain Awareness week
DemenFa project and other mulF-insFtuFonal studies
Brain iniFaFve?
24

Funding: Private

25

Biography of a grant

26

Biography of a grant
Submission and review
~1million to 10 million
rupees, over 3 years
Review processes vary,
evolving
Permissions
RestricFons
ClaricaFons
Revisions
LimitaFons

Opera2on
SancFon
Release
When and how much
Spending schedule

Reports
Revisions

Final report
Follow up?

27

DirecFons
Challenges/Opportuni2es
InsFtuFonal
Academic (Leadership)
Economic
Civil society
Engagement
ExpectaFons
Ethics

The role of IBRO

Advisors and reviewers
Mentoring, parFcipaFng,
promoFng, diversifying
Travel. CollaboraFve
funding. Lobbying.
Outreach models and support
Publicity content and training
ParFcipaFon

28

Neuroscience in India

Thank you

29

Neuroscience funding situation and advocacy

activities in Sri Lanka

Ranil De Silva
President, Neuroscience Society of Sri Lanka

rincipal Inves9gator, Gene9c Diagnos9c & Research Laboratory and Human Brain Tissue and DNA Repository,

Chairperson, Neuroscience Module CommiHee,

Faculty of Medical Sciences,
University of Sri Jayewardenepura,
Sri Lanka.
Email: ranil@sjp.ac.lk

Neuroscience Research in Sri Lanka- Current situa4on

Unique
Resources

Collabora4ons

Community
awareness

Funding

Ageing and
Neuromuscular Diseases

Natural Products in vitro and

vivo of an4oxidant, an4-
inammatory, Neuroprotec4v
and memory enhancing abili4
Medita4on

NeuroGene4cs

Bio-repository of DNA/Gene
Bank

Brain Banking

One and only Human

Brain Bank in Sri Lanka -
Age Related Cytoskeletal
Pathology - 76 ageing
brain 4ssue

Stroke 905
Cerebral Arterial Circle 456
Duchenne Muscular Dystrophy
(DMD)- 90
Spinal Muscular Atrophy
(SMA)- 30
Parkinson Disease(PD) 230
Others -65
Control 300

Unique Resources Available

. Human Brain Tissue Repository

The one and only Brain Bank in Sri Lanka with
aging and diseased brain 4ssues stored in formalin and -80C

A Secreted Frizzled Related

Protein
In Human Brain, SFRP-4

The Cerebral Arterial

Circle (Circle Of Willis/
COW) 456 Pa4ents

Asia Oceanic Brain Bank Network?

Age Related Cytoskeletal Pathology

In Human Brain:
76 aging brain 4ssue
Pathologies:
1. Alzheimers Disease
2. Parkinson Disease
3. Progressive Supranuclear Palsy
4. Demen9a with Lewy Body Disease
5. Mul9ple System Taupathy with Demen9a
6. Cerebral Amyloid Angiopathy
7. Argyrophilic Grain Pathology
8. MTHFR
9. Factor VL
10. Prothrombin (FII)
1.
2.
3.

MTHFR
Factor VL
Prothrombin (FII)

Genes:

n6a Prevalence in Developing Countries

South Asia
q23.2% of the world popula9on in 20
q4.5 million people aected with dem
in 2010 (35.6million world wide)
qAnnual cost US$ 4.04 billion in 2010
(world wide US$ 604 billion)
qOver 126 million people aged >60yrs
2011
v 13% - Sri Lanka
v 8% - India
v 7% - Bhutan, Bangladesh & Maldiv
v 6% - Nepal & Pakistan
v 4% - Afghanistan

2. Blood/DNA/Data Bank

A KEY to ne
Gene4c
Findings?

Socio-demographic and Clinical data of over 1500 pa4ents

Disease

oke

kinson disease (PD)

pranuclear Palsy

heimers Disease (AD)

# of pa4ents
905
230
4
9

chenne Muscular Dystrophy (DMD)

90

n9ngton Disease (HD)

21

nocerebellar Ataxia (SCA)

20

sons Disease

gile X Syndrome

otonic Dystropy

edrichs Ataxia

ntatorubro-Pallidolusyian Atrophy

nal Muscular Atrophy (SMA)

3
3
3
3
1
30

ntrol

300

al

1622

More prevalent in younger ages:

17.25% (35 - 44 years)
48.25% (45 - 64 years)
23.36% (65 - 74 years)
11.14% (75 years)

Reports of occupa9onal Hazards:

Gold cyanide inges9on
Mn exposure for 25 years

Iden4cal Twins with DMD:

Fossil evidence: earlies

Homo sapiens
from South Asia

Indigenous Popula4on
(Veddah)
Gene4c admixture
by Indians

7th reported case worldwide.

A female with DMD:

Age 11 yrs

High familial disease clustering;

2 families

1 pa9ent's mother and her twin

sister with SCA

Consanguinity
20%
European Gene4c
Admixture
(16 - 20th century)

Portuguese
Dutch
Bri9sh

 Mul4disciplinary, Innova4ve Research Inves4ga4ng

ndings with Ceylon Natural

ucts;
Completed Two PhDs;

on Black
Tea






eylon
Tea
en



eylon


namon

amomum
lanicum

Total content of an9oxidants

in green tea and black tea
are highest in Sri Lankan
products compares to other
manufacturers of dierent
countries
People who had consumed
tea hold a compara9vely
l o w e r i n A D r e l a t e d
pathological stages/grade
t h a n w h o h a d n e v e r
consumed tea.
The Ceylon Tea Extract
showed 68.27.8% of TEAC
v a l u e c o m p a r e d w i t h
Ascorbic Acid.
Worlds largest (90%)
producer & exporter.

Meditation in Sri Lanka

An in-depth study within the philosophico-litera

aspects of medita4on can help propose testable
hypotheses within the scien4c domain. Awasth
al. (2013)
Iden4ca4on and isola4on of the components o
aken4on within various medita4on methods, co
be a promising start. Sedlmeier et al. (2012),

RAJAGALA in Sri Lanka

Buddhist temple complex originated in th
3rd c B.C. had been in use for a number o
centuries where The mountain the range
doHed with hundreds of caves.
Unique study site for mul9disciplinary
research on,
Mind relaxa9on.
Medita9on and Brain Func9on.
Mindfulness
US Ambassadors Fund- $ 100,000
USJP for Conserva9on of the Monastery

3 Interna4onal Memorandum of Understandings, MoU

1st MoU signed by the;

European Graduate School of

Neuroscience, EURON Netherland

ociated Partner status for The Faculty of Medical

ences, USJP within EURON [
//www.euronschool.eu/page/119/Associated_partners/]-Only other
tners from the whole of Asia, esteemed universi9es
m Japan and Korea
Mul4disciplinary MSc./PhD and Double Doctoral Degree
gram in Neuroscience / Neuro-chemistry -1st Double
toral PhD Degree will be awarded end of March 2015
P eligible for EUR 54 Billion

r. Harry Steinbusch; Director, School for Mental Health

euroscience at Maastricht University, Netherlands
and Dr. N. L. A. Karunaratna, The Vice Chancellor, USJP
December 2013

2nd & 3rd MoU signed by the;

University of Chinese Academy of Sciences, UCAS, China

CAS -TWAS Presidents Postgraduate

Fellowship Programme-

A Double Split MSc /PhD Degree bet

UCAS, China and USJP, Sri Lanka

Prof. Zhu Xiangbin, Assistant President ,UCAS and

Dr. N. L. A. Karunaratna, The Vice Chancellor,
USJP on 23rd January 2014

Prof. Wu Yueliang, Execu9ve Vice-Presiden

UCAS and Dr. N. L. A. Karunaratne, The Vice
Chancellor of the USJP on 16th September
2014

For students to pursue PhD degrees at UCAS, the

University of Science and Technology of China (USTC)
and Ins9tutes of CAS around China.

Collaborations for Academic Guidance, Training &

Technology Transfer
WUR: 13

WUR: 29

WUR: 25

WUR: 26

WUR: 95

WUR: 98

WUR: 168
WUR: 194

WUR - World University Ranking 2013

(hHp://www.9meshighereduca9on.co.uk/world-university-ran

Interna4onal Fellowships

Received by fully Interna4onal Scholarships for the Research Assistants from the Gene4c
Diagnos4c & Research Laboratory and Human Brain Tissue Repository/USJP, Sri Lanka

Canada- 01
Switzerland - 01
USA - 01

China - 04
India - 13

Hong Kong - 01
Malaysia - 01
Singapore - 02
Australia-01

Total 25

For training abroad/

aHending interna9onal
training workshops and
conferences to 25
Research Assistants
from 2006 2014

Our Contribu4on to Promote Neuroscience/

Brain Science in Sri Lanka

rain Awareness Day by Prof. Ann and Gabor Kato

War torn North

Tsunami South

2009

2006

2. Six day Interna6onal Neuroscience Workshops in 1999, 2004,

2006 and 2012
1999

2012

2004

2006

2006

4), six to eight (6 - 8) day Interna9onal Neuroscience Workshop in 1999,2004, 2006 and 2012 with 40 Resource Perso
t academic stature (Australia, India, Italy, Israel, Canada, Hong Kong, Sweden, Netherlands, Japan, Korea, Singapore,
K). Par9cipants at this workshop were from Sri Lanka (151) and neighboring countries (20) from; Bangladesh, India,
an, Singapore, Thailand and Sweden, UK. (full fellowships including travel to selected par9cipants were oered).

No specic category for

Neuroscience
Not sucient for
advanced research.
Do not promote high
impact publica9ons.
Priority given to paper
work other than output.

Interna9onal

Local

rdles to Obtain Funding

Under representa9on of
researchers based in
developing countries
Need solid interna9onal
collabora9ons
Problems in eligibility
criteria.
Mostly Target High-Tec
Research.

CHALLENGES
Local

Insucient
Government funds
Lack of Private-Govt
CollaboraLon and Non-
Govt Funding Bodies.

CENTRE FOR
NEUROSCIENCE,
SRI LANKA
Interna9onal

HIGHLY SOLICITED
InternaLonal
CollaboraLon
High Tec Research

ntre for Neuroscience, Sri Lanka..Cont.

Cost Eec4ve Gene4c
Diagnos4c and carrier
Detec4on.
Income Genera4ng
Neurogene4c and
Neuroimaging
Diagnos4c facility

Expand the established

human Brain Bank

Maximize the usage of

the equipment

Mul4disciplinary
Innova4ve Research
Inves4ga4ng
CENTRE FOR
NEUROSCIENCE

Human Resource
Development

Solidify already
Established
Collabora4ve
Rela4onships

gether we can make a dierence

Local &
interna9onal
funding

Unique
resources in
SL

Scien9c
collabora9ons

Centre for Excellence in Neuroscience Leading to,

1. Discovery of new genes
2. Low cost diagnostics & gene therapy
3. Natural product based drug discovery
4. Research in Mindfulness/ Mind Relaxation

1st IBRO APRC Global Advocacy Workshop

3-4 Feb 2015

Neuroscience funding and research in Iran

Saeed Semnanian MD PhD
Department of Physiology
Tarbiat Modares University, Tehran, Iran

Where we stand
Weak and strong points
Influential people and institutions
Funding institutions

Iran
Population: 80 million
4.5 million students (%60 females)
R & D expenditure (% of GDP. 2014): %0.5

Iran

Scopus

Year

Irans
world
rank

Articles
(documents)

% of
world
production

ISI
Irans
Irans
rank in Articles
world
(documents)
the
rank
region

% of
world
production

Irans
rank in
the
region

2012

39384

17

1.5

28301

20

1.39

2013

40011

17

1.5

3044

21

1.37

2014

36441

16

1.54

27336

20

1.5

Neuroscience research in Iran

15 years ago Iran had a rank of 49 in the world

according to the SJR ranking

Now Iran ranks 37 in the world and 3 in the Middle

East

Fereshteh Motamedi PhD

Iranian academy of Medical Sciences member

Previous FAOPS Vice President
Previous FAONS President
Previous IBRO APRC (Asian Pacific Regional
Committee) member

Research Institutes

IPM - Institute for Research in Fundamental Sciences

The Institute for Cognitive Science Studies (ICSS)

The institute was

founded in 1997

Graduate Programs:
The Master programs:
1- Cognitive Psychology
2- Mind, Brain, and
Education

PhD programs:
1- Cognitive Neuroscience
2- Cognitive Psychology
3- Cognitive Linguistics
4- Cognitive Modeling
5- Philosophy of Mind

The first group of ICSS doctoral students graduated in

February 2011.

The Neuroscience Research Center

Shahid Beheshti University of Medical Sciences

Sina Hospital MS research center

Imam Khomeini Hospital Brain Diseases Research Center

The Scientific Societies

Iranian Society of Physiology and Pharmacology (ISPP)

National non-profit professional organization, founded in 1968

The Congresses

Scientific Journals

Basic and Clinical Neuroscience Journal

Physiology and Pharmacology journal

The official publication of the Iranian Society of Physiology and
Pharmacology

Advances in Cognitive Science

The flagship of the institute is
Advances in Cognitive Science.
First appeared in spring 1999,
the quarterly journal is a
prominent means in Farsi for
scholars,), issues of the journal
often contain, review articles,
book reviews, and a list of the
latest books and articles
published in and out of Iran in
the areas of cognitive sciences.
The journal also includes an
English section, which
provides abstracts of the full
pieces printed in Persian.

Leading Institutions in Neuroscience

Funding

Universities
Research Institutes
Cognitive Science and Technologies Council
Iran National Science Foundation (INSF)

Cognitive Science and Technologies

Council

 Cognitive Science and Technologies Council was

Founded in 2011
Leading Policy-making and Granting Agency Nationwide
To Plan for and Monitor Advancement of CST in
Iran
To Provide Grants to Universities, Institutions,

Enterprises, Faculty Members, Students, Activists

and Researchers
To Develop National and International Collaborative
Environments for Researchers from Different
Disciplines of CST
To Promote Human Resources in CST via Formal
and Informal Education Programs

Cognitive Science and Technologies

Council Main Ten Goals
1.
2.

3.
4.
5.

Developing a national network of scientists, researches,

organizations, institutions, and companies that are
involved in the study of CST.
Promoting cooperation of Iranian scientists, research
centers and universities with those in other parts of the
world by supporting student exchange, visiting professor
exchange, joint graduate programs, joint projects, and
joint conferences.
Publishing and translating books and journals devoted to
the advancement of CST.
Promotion of basic and fundamental research on brain
and its cognitive functions.
Developing cognitive rehabilitation programs to enhance
mental fitness and improve cognitive capabilities.

Cognitive Science and Technologies

Council Main Ten Goals
6. Utilizing and developing advanced technologies and to
conduct a vast range of research from brain & behavior to
computer and machine learning.
7. Developing authentic protocols and techniques for
treatment of mental disorders and cognitive deficiencies.
8. Developing artificial intelligent systems inspired by
human brain and its cognitive functions.
9. Developing a model of cognitive education based on the
findings of cognitive psychology and cognitive science.
10 . Promoting research in philosophy of mind, as it relates
to the Islamic philosophy and tradition.

Iran National Science Foundation (INSF)

Iran National Science Foundation (INSF)

INSF is an Iranian government agency that supports

fundamental research and education in all fields.

The assets of this foundation are supplied via

governmental aids, bank facilities, and investments

of its own surplus assets, receiving financially and
non-financially from true or legal persons.

Neuroscience is one of the priorities for INSF. All of

the neuroscientists in Iran have the opportunity to
submit their projects proposal to INSF.

The RIKEN effect

Masao Ito
MD PhD

Saeed Semnanian MD PhD

Thomas Launey, Ph.D.

Keiji Tanaka, Ph.D.

Farshad A. Mansouri PhD

Hosein Esteky MD PhD

Tadaharu Tsumoto, M.D., Ph.D.

S. Javad
Mirnajafi Zadeh PhD

Mir-Shahram Safari PhD

Abdolrahman Sarihi PhD

The IBRO effect

Jack McMahan

Visiting Lecture Team

Programme (VLTP)

Professor John Nichols

16th Iranian Physiology &
Pharmacology Congress
Tarbiat Modares University, 2003

Professor Alasdair Gibbs

Patch Clamp Workshop
Tarbiat Modares University, 2004

Professor Jack McMahan

19th Iranian Physiology & Pharmacology Congress
Shaheed Beheshti Med Sci University, 2009

1st IBRO Tehran Associate School of Neuroscience, 2006

1st IBRO Tehran Associate School of Neuroscience, 2006

Professor Kaneko, Past IUPS President

Tarbiat Modares
University

Neuroscience Research Center

Shahid Beheshti Univ. Med. Sci

Institute for Research in

Fundamental Sciences

2nd Tehran IBRO School of Neuroscience

May 12 23, 2012

Organizers:

Fereshteh Motamedi
Honorary Director

Saeed Semnanian
Director

Mahyar Janahmadi

Javad Mirnajafi-Zadeh

Masoumeh Jorjani

Hossein Esteky

Mohammad Javan

Abbas Haghparast

Alireza Mani

Hossein Azizi

Lecturers:

Peter Illes
GERMANY

Patrizia Rubini
GERMANY

Hossein Baharvand
IRAN

Fusao Kato
JAPAN

Thomas Launey
JAPAN

Hossein Esteky
IRAN

Vahide Abdolazimi
IRAN

Sakineh Alijanpour
IRAN

Mohammad Amani
IRAN

Abdul Haque Ansari

NEPAL

Ronak Azizibeigi
IRAN

Siamak Beheshti
IRAN

Muhammad Bin Sayeed

BANGLADESH

Omer Celik
TURKEY

Mojtaba Dolatshahi
IRAN

Shima Ebrahimi
IRAN

Rasool Ghasemi
IRAN

Maryam Ghiasvand
IRAN

Lilia Hambardzumyan
ARMENIA

Farina Hanif Chhipa

PAKISTAN

Mansoureh Hashemi
IRAN

Tanzeel Huma Anwar

PAKISTAN

Maryam Jafarian
IRAN

Huma Jawed
PAKISTAN

Hassan Zaffer MirSajad

Farzaneh Nazari
IRAN

Masoumeh Nozari
IRAN

Mohammad Torabi Nami

IRAN

Hakimeh Saadati
IRAN

Abdulhadi Cihangir Uguz

Participants:

INDIA

TURKEY

1st IBRO/APRC Iranian Associate School of Cognitive Neuroscience

Functional Human Brain Mapping May 22-28, 2015
Tehran, Iran

Tarbiat Modares University

Faculty of Medical Sciences
Tehran, Iran

1st IBRO Tehran Associate School of Neuroscience, 2006

Dr Touqueer Ahmad, Pakistan

Science and Technology Development in Iran

PhD programs in neuroscience have been
established in many universities in Iran
(It started from 2007)
Research Institutes which cover Neuroscience and
also Cognitive Science Studies
Scientific congress, workshops and symposia

Science and Technology Development in Iran

PhD programs in neuroscience have been
established in many universities in Iran
(It started from 2007)
Research Institutes which cover Neuroscience and
also Cognitive Science Studies
Scientific congress, workshops and symposia