Geraldine D.

Lanuza

3Bio3 Feb 10 2015

FIBRODYSPLASIA OSSIFICANS PROGRESSIVA

Mehul M Gosai1, Hareshwaree B Hariyani2, Monil Shah3, Payal H Purohit4,
Mihir A Sadadia5

Abstract
Fibrodysplasia ossificans progressive or FOP is a rare genetic disease
characterized as the formation of bone in muscles, tendons, ligaments, and other
connective tissues. There was a report of a male child with bilateral Hallux Valgus
commonly called a bunion, is a deformity characterized by medial deviation of the great
toe, and a firm swelling of the lower back region since birth. At age 3, a gradual
progression of the restriction of neck movement occurred, and within a year restriction
involved multiple joints, including the hip, shoulder, spine and knee occurred. Bending
forward, squatting or turning of the head to either side became impossible for the
patient. The patient also developed an acyanotic congenital heart disease, a congenital
disorder manifested with left to right shunting and obstructive lesions. Multiple foci
ossification developed on shoulder, the right hip and the lower back region. Patient has
yet to show development of episodes of crisis and all swellings and restriction were
painless. Only few similar case reports were found in other Brazilian literature. The
criteria for diagnosis and the importance of management and treatment were reviewed.