GROUP 1

Pathophysiology, clinical manifestations, nursing and

medical management of sexually transmitted diseases

MANAGEMENT OF
PATIENTS
WITHREPRODUCTIVE
DISORDERS

Genital herpes

Genital herpes or
Type 2 Herpes
Simplex is a
recurrent viral
infection primarily
affecting the genital
area. It causes
painful clusters of
small ulceration.
(Pathophysiology made
incredibly easy, 1998)

Pathophysiology
The causative agent, Herpesvirus hominis,
is transmitted during sexual contact.
(Pathophysiology made incredibly easy, 1998, pg. 49-50)

Virus fuses
to host cell

Viral
replication
and structural
proteins
synthesized

Viral DNA
released into
cytoplasm OF
host cell

Virus releases
enzyme

Enzymes
inhibit hosts
protein
synthesis

Virion
transported
to cell
surface

Clinical Manifestation

Tingling
Malaise
Dysuria
Dyspareunia/ Coitus
- Painful intercourse

Leukorrhea (in females)

- white vaginal discharge containing mucus and pus cells
(Pathophysiology made incredibly easy, 1998)

Clinical Manifestation
contd

Localized fluid filled vesicles occur on cervix,

labia, perianal skin, vulva and vagina, in
women.

Vesicles appear on glans penis, foreskin, and

penile shaft.

According to Pathophysiology made incredibly

easy (1998) lesions on mouth and anus or
inguinal swelling may manifest.

Treatment

Pharmacologic
-Acyclovir, Valacyclovir, Famciclovir
-Calamine lotion soothe lesions on labia and skin
-Lidocaine in mouthwash for oral lesions

Non- Pharmacologic
- Patient teaching on disease spread, transmission
prevention, self care during outbreaks.
- Emphasize abstinence until complete healing
occurs

Points to Note

The risk of cervical cancer is increased

in women with genital herpes.

Virus becomes latent inside cell where it

replicates and redevelops lesions even after
cell death.

Petroleum based salves or dressing can

cause viral spread and slow healing.
(Pathophysiology made incredibly easy, 1998)