From: AgeAgeing.2010July39(4):412423.

Publishedonline2010April13.doi:10.1093/ageing/afq034
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Table5
Diagnosisofsarcopenia:measurablevariablesandcutoffpoints
Criterion

Muscle
mass

Measurement Cutoffpointsby Referencegroupdefined

method

gender

DXA

Skeletalmuscle

Basedon2SDbelowmeanofyoungadults(Rosetta

Ref

[66]

massindex(SMI) Study)
(Appendicular
skeletalmuscle
2
mass/height )
2
Men:7.26kg/m
Women:5.5
2
kg/m
SMI

(ASM/height )

Basedonsexspecificlowest20%ofstudygroup(n=

[17]

2,976)

2
Men:7.25kg/m
Women:5.67
2
kg/m
SMI

Basedonsexspecificlowest20%(HealthABCStudy) [68]

(ASM/height )
2
Men:7.23kg/m
Women:5.67
2
kg/m
Residualsof
linearregression
onappendicular
leanmass
adjustedforfat
massaswellas
height
Men:2.29
Women:1.73

Basedonsexspecificlowest20%(HealthABCStudy) [68]

BIA

SMIusingBIA

Basedon2SDbelowmeanofyoungadultsinstudy

predicted

group(n=200)

[8]

skeletalmuscle
mass(SM)
equation

2
(SM/height )
2
Men:8.87kg/m
Women:6.42
2
kg/m
SMIusing

BasedonstatisticalanalysisofNHANESIIIdataon

absolutemuscle older(60years)menandwomen

[19,
67]

mass,not
appendicular
musclemass
(absolutemuscle
2
mass/height )
Men:
Severe
sarcopenia8.50
2
kg/m
Moderate
sarcopenia8.51
2
10.75kg/m
Normalmuscle
2
10.76kg/m
Women:
Severe
sarcopenia5.75
2
kg/m
Moderate
sarcopenia5.76
2
6.75kg/m
Normalmuscle
2
6.76kg/m
Muscle

Handgrip

strength

strength

Men:<30kg

Basedonstatisticalanalysisofstudygroup(n=1,030) [13]

Women:<20kg
Men:
BMI2429
kg
BMI24.126
30kg
BMI26.128
30kg

Basedonquartilesofstudygroup(n=5,317)

[27]

BMI>2832
kg
Women:
BMI2317
kg
BMI23.126
17.3kg
BMI26.129
18kg
BMI>2921
kg
Physical

SPPB

SPPB8

performance

SPPBscoreisasummationofscoresonthreetests:

[62]

Balance,GaitSpeedandChairStand.Eachtestis
weightedequallywithscoresbetween0and4
quartilesgeneratedfromEstablishedPopulationsfor
EpidemiologicStudiesoftheElderly(EPESE)data(n=
6,534).ThemaximumscoreontheSPPBis12
SPPB06Low
performance
SPPB79
Intermediate
performance
SPPB1012
High
Performance
Gaitspeed

6mcourse

BasedonstatisticalanalysisofHealthABCparticipant [63]

GS<1m/s

data

6mcourse

BasedonROCcurvesanalysisofHealthABCdata

[63]

GS<1.175m/s
15ft(4.572m)
course
Men:
Height173
cm7s(GS<
0.65m/s)
Height>173
cm6s(GS<
0.76m/s)
Women:
Height159
cm7s(GS<
0.65m/s)

Basedonquartilesofstudygroup(n=5,317)

[27]

 Height>159
cm6s(GS<
0.76m/s)
4mcourse

Basedonstatisticalanalysisofstudygroup(n=1,030) [13]

GS<0.8m/s
8ft(2.438m)
course
Quartilesof
performance:
0.43m/s
0.440.60m/s
0.610.77m/s
0.78m/s

BasedonSPPBvalues