Spinal

Cord

Prepared by : Adeeb Mahmoud

Jabareen
Supervision of : Dr. nimer khraim

 Part

of the CNS.
Extends from the foramen magnum to
the end of lumbosacral.
Main pathway for information flow to
and from the brain

 Spinal

cord contain central canal, gray

matter, white matter

That Covered by three membranes called

(meninges):
1-dura mater 2-arachnoid mater 3-pia mater

1-Dura mater:
Contain

thick collagen bundles and

elastic fibers.
The dura mater also contains
fibrocytes, nerves, lymph and blood
vessels
The inner surface of dura mater is
lined by multiple layers of flattened
fibrocytes to which outer cells of the
arachnoid membrane cell.

2-Arachnoid(arachnoid membrane)
Consists

of outer layers of flattened

fibrocytes and inner, loosely arranged,
flattened fibrocytes associated with small
bundles of collagen fibers.

3-Pia mater
Highly

vascular layer that covers the

spinal cord.
It is characterized by wide intercellular
spaces containing variable amount of
interlacing collagen fibers and fine
elastic networks with a few fibrocytes,
lymphocytes, and mast cells.

 A basal

lamina separates pia mater

collagen from the underlying glial
limiting membrane
The pia mater is covered on its outer
surface by a layer of flat fibrocytes.
Together

with arachnoid, pia mater

bounds the subarachnoid space, which
contains cerebrospinal fluid.

 The

entire subarachnoid space,

including the surfaces of nerves and
vessels that transverse space, is lined
by flattened fibrocytes joined zonulae
adherens.

 The

fibrocytes are capable of

phagocytosis, and macrophages are
spordically found on the lining of the
subarachnoid space.

 The

fibrocytes layer lining the

subarachoind space lacks a basal
lamina, a limited exchange of fluid ,
small molecules, and
immunocompenent cells between the
cerebrospinal fluid and the arachnoid
and pia compartments is possible.

THE END