RETINOPATI ANEMIA

Farmitalia Nisa Tristianti

122010101037

Anemia px hematologi manifestasi penurunan tingkat sirkulasi darah merah &/ penurunan hb.
Gx umum anemia lemah dan kelelahan

Manifestasi tidak spesifik dan hamper mirip HTN/DM retinopati.

Perubahan pada retina karena anemi cotton wool spot, vena berliku, dan hemoragik pada retina
dan koroid.

Manifestasi

Anoxia

venous stasis

Angiospasm

increased capillary permeability

thrombocytopenia

shock optic neuropathy

Long-standing anemia FROM Vitamin B12 and/or folate deficiency may also present with optic neuropathy.

anemic retinopathy is almost always reversible correction of the anemia.

Pathophysiology

Molekul Hb erit func transport O2 ke jaringan.

sickle cell retinopathy vasoocclusion retinal hypoxia, ischemia,

infarction, neovascularization, and fibrovascularization.

In sickle cell anemia, the amino acid substitution valine for glutamate occurs.

This substitution erythrocyte rigid sebagian tanggungjawab

vasoocclusion.

Vasoocclusion interaction between sickled cells and the vascular

endothelium.

The adherence of sickled cells to the endothelium inflammatory process

with the release of inflammatory agents.

The result of this cascade is vascular stasis, hemolysis, and vasoocclusion of

the capillary beds.

anemia and thrombocytopenia is likely to produce retinal hemorrhages in a

majority of patients

A ce 36 th vegan def as folat utk pembentukan erit