Name: RAFAEL, DUNE VIENIS KAREN N.

Year & Section: BS-Pharmacy 4A

Group No.: _____________________ Date Started: November 27, 2009
Date Submitted: November 23, 2009

Exercise No. 5
PREPARATION OF SIMPLIFIED CEPHALOSPORIN SKIN TESTING

I. Objectives:
a. Prepare a simplified cephalosporin for skin testing,
b. Label the solution properly,
c. To give brand names of cephalosporin drugs, and
d. To identify the positive signs showing allergic reaction.

II. Data Output:

The label of the preparation:

Saint Luke’s Hospital
Father Selga Street, Davao City
Patient’s Name: Robert John R. Rafael Age: 23 Sex: Male
Attending Physician: J. Noveno, MD. Room No.: 47

Ceftriaxone sodium (Medcef®)

1 mcg/ml solution for Skin Testing

Prepared by: Dune Rafael, RPh

Pharmacist

III. Answers to Questions:

1. Give the brand name of the following cephalosporin:

Generic Name of Brand Names Available in the Philippines

Cephalosporin
a. Cefotaxime Axitof vial®, Cefox vial®, Ceptax vial®, Cetaxima vial®, Cladex
vial®, Clafetam vial®, Clafojen vial®, Claforan vial®, Clafoxim
vial®, Clinbaxef vial®, Fotexin vial®, Foximet vial®, Haxim
vial®, Lac-xim vial®, Losforexan vial®, Ofetaxim vial®, Pantaxin
vial®, Sefotak vial®, Taxim vial®, Zalor vial®, Zefocent vial®
b. Cefazolin Biocef vial®, Cifoxim vial®, Cizo vial®, Cloviz vial®, Fazol vial ®,
Fonvicol vial®, Hazolin vial®, Ilozef vial®, Leklin vial®, Lozan
vial®, Maxcep vial®, Megacef vial®, Novecef vial®, Oryant
vial®, Plezolin vial®, Refzolin vial®, Samarial vial®, Stancef inj®,
Zalulin vial®, Zofadep vial®, Zolival vial®
c. Cefalexin Airex cap, drops & susp®, Bacilexin cap, drops & susp®,
Bandax cap & drops®, Benlexin cap®, Bloflex cap®, Canelin
cap®, Cefalin Capsule®, Cendalex cap®, Ceporex®, Civalex®,
Clephin®, Difalex®, Edexin®, Eliphorin®, Exel®, Fablex®,
Falex®, Falteria®, Forexine®, Infexin®, Ivynall®, Keflex®,
Lafayette Cefalexin cap®, Lewimycin®, Lexum®, Lyceplix®,
 Madexin®, Medilexin®, Medoxine®, Mexin, Nefadon®,
Neolecsin®, Nerfalex®, Oneflex, Pediaflex®, Pharex
Cefalexin®, Respinal®, RiteMED Cefalexin®, Selzef®, Sorlex®,
Xeface®, Xinflex®, Zepharyl®, Zeporin®, Zepotex®, Zexanta®
and Zinace®
d. Cefadroxil Drolex®, Drozid®, and Lexipad®
e. Cefuroxime Aeruginox®, Altacef®, Ambixime®, Axet®, Axurocef®,
Cefogen®, Ceftil®, Cefucil®, Cefumax®, Cervin®, Cidokez®,
Cimex®, Clovixime®, Cosef®, C-Tri T®, Curecef®, Darcef®,
Ecocef®, Elixime®, Emixor®, Eurimax®, Finax®, Furocef®,
Furocem®, Furomax®, Furoxim®, Furoxy®, Harox®, Ifurax®,
Infekor®, Jectocef®, Kefezy®, Kefox®, Kefstar®, Kefsyn®,
Keunzef®, Lasuzef®, Laxinat®, Medxil®, Mircozef®, Panaxim®,
Plerozef®, Profurex®, Proxim®, Rexofen®, Rezafil®, RiteMED
Cefuroxime®, Romicef®, Rovix®, Roxetil®, Roxicef®, Roxime®,
Shincef®, Xorimax®, Zefur®, Zefuxim®, Zegen®, Zinacef®,
Zinnat®, Zurenix®
f. Cefaclor Aczebri®, Ceclobid®, Ceclor®, CFC®, Clorcef®, Ephron®,
Lorcef®, Pharex Cefaclor®, RiteMED Cefaclor®, Remedlor®,
Surecef®, Vefarol®, Versef®, Verzat®, Xelent®, Yucro®,
Zeclor®, Zynolex®, Zyrcef®
g. Cefamandole Mandol®
h. Cefoxitin Dintaxin®, Haxotin®, Monowel®, Pacetin®, Panafox®,
Pharmawealth Lab Cefoxitin Sodium®, Zepax®
i. Ceftriaxone Acrexon®, Afrixon®, Armak®, Bactrias®, Cef-3®, Cefotrim®,
Ceftrox®, Ceptrocin®, Cikedrix®, Clovizone®, Cryaxon®,
Dintri®, Efekton®, Eroxet®, Eurosef®, Fazactin®, Fenadef®,
Forgram®, Haxon®, Kenaxef®, Keptrix®, Maxeftin®, Medzef®,
Megion®, Monocrin®, Norcephin®, Novosef®, Noxoram®,
Pantrixon®, Recephin®, Rocephin®, Roxifen®,
j. Ceftazidime Bactizef®, Ceftaz®, Fortum®, Flazidem®, Zeptrigen®

2. What are the positive signs that show allergic reaction?

Since our subject is about skin testing, the positive signs that show allergic
reaction is the reddening and swelling of the skin [ CITATION Med02 \l 1033 ].

3. What are the emergency steps to be done in the presence of anaphylactic reaction
while performing skin testing?

There is only one rapidly effective treatment for anaphylaxis – epinephrine by

injection. Epinephrine is adrenaline and it rapidly reverses anaphylactic symptoms. It is
typically given through an automatic injection device. The most common injection site is
the thigh [ CITATION Web09 \l 1033 ].

In addition to epinephrine, treatment for shock includes intravenous fluids and

medicines that support the actions of the heart and circulatory system. After a person in
 shock is stabilized, antihistamines and steroids may be given to further reduce
symptoms [ CITATION Web09 \l 1033 ].

IV. Conclusion:

Skin testing can help confirm the substances that cause severe allergic reactions. In
preparing admixtures for skin testing, aseptic techniques should be practiced in order prevent
contamination. Skin testing admixture should be prepared right before the skin testing is
conducted to assure freshness of the admixture.

In the advent of an anaphylactic shock during skin testing, epinephrine is the effective
treatment for anaphylaxis. In addition to epinephrine, treatment for shock includes intravenous
fluids and medicines that support the actions of the heart and circulatory system. After a
person in shock is stabilized, antihistamines and steroids may be given to further reduce
symptoms.

Bibliography
 MedicineNet.com. (2002, April 16). Skin Test For Allergy. Retrieved December 55, 2009, from
MedicineNet.com Website:
http://www.medicinenet.com/skin_test_for_allergy/article.htm#3whatis

 MIMS Philippines. (2009). Methycobal amp. Retrieved November 22, 2009, from MIMS.com:
http://www.mims.com/Page.aspx?
menuid=mng&name=Methycobal+amp&h=methycobal&CTRY=PH&searchstring=Methycobal+a
mp

 RxMed. (2009, January 15). Nipride. Retrieved November 22, 2009, from RxMed.com:
http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-
%20Monographs/CPS-%20(General%20Monographs-%20N)/NIPRIDE.html

 WebMD. (2009, February 05). Allergies and Anaphylaxis. Retrieved December 05, 2009, from
WebMD.com: http://www.webmd.com/allergies/guide/anaphylaxis