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COLLEGE OF NURSING
1962 J.P. Laurel National Highway, Lipa City
Tel. (043)756-5555, 756-2491, 756-2391 loc 270
GENERIC NAME
DRUG STUDY
BRAND NAME
MAJOR DRUG
CATEGORY
Amlodipone 10 mg every
after dinner
Norvase
DRUG ACTION
USES
SIDE
EFFECTS/ADVERSE
REACTIONS
Binds to dihydropyridine
and nondihydropyridine
cell membrane receptor
sites on
myocardial and vascular
smooth-muscle
cells and inhibits influx of
extracellular calcium
ions across slow calcium
channels.
SIGNIFICANT DRUG
INTERACTION
beta blockers: Possibly
excessive hypotension
fentanyl: Increased risk of
severe hypotension
and increased fluid volume
requirements
Antihypertensive
Headache
Peripheral edema
Nausea
Muscle cramps
Rash
Pruritus
CONTRAINDICATIONS
Hypersensitivity to
amlodipine or its
components
during surgery
NURSINGMEDICATION MANAGEMENT
ASSESSMENT
Assess for heart failure, report signs
and symptoms to prescriber.
EDUCATION
Tell patient to take missed dose as
soon as remembered and next dose
in 24 hours.
Tell patient to immediately notify
prescriber of dizziness, arm or leg
swelling, difficulty breathing, hives,
or rash.
Suggest taking amlodipine with
food to reduce GI upset.
Advise patient to routinely have
blood pressure checked for possible
hypotension
INTERVENTION
Use amlodipine cautiously in
patients with heart block, heart
failure, impaired renal function,
hepatic disorder, or severe aortic
stenosis.
Monitor blood pressure while
adjusting dosage, especially in
patients with heart failure or severe
aortic stenosis.
EVALUATION
Review all other significant adverse
reactions.