A 23 YEAR OLD WOMAN HAD

COMPLAINTS OF WEAKNESS AND

LETHARGY. HER HAEMOGLOBIN LEVEL
WAS 7 GM / DL. HER BLOOD WAS FOUND
TO CONTAIN LARGE, ABNORMAL
IMMATURE ERYTHROCYTES. THIS
WOMAN HAD A HIGHLY ELEVATED
EXCRETION OF FIGLU, A METABOLITE OF
HISTIDINE IN URINE
1) WHAT IS THE PROBABLE CAUSE OF
THE ANEMIA
2) WHICH TYPE OF ANEMIA DOES
THE PATIENT SUFFER FROM
3) WHAT IS THE BIOCHEMICAL BASIS



A FOUR YEAR OLD CHILD IS
CHARACTERIZED BY BONE DEFORMITIES
DUE TO INCOMPLETE MINERALIZATION,
RESULTING IN SOFT AND PLIABLE BONES.
THERE IS DELAY IN TEETH FORMATION.
THE CHILD IS DIAGNOSED TO HAVE
RICKETS
1) HOW MANY TYPES OF RICKETS ARE
THERE
2) STATE THE CAUSE OF THE DISEASE
3) HOW CAN THE DISEASE BE TREATED






A PATIENT IN THE HOSPITAL HAD
SEIZURES AND USUALLY APPEARED TIRED
AND WEAK. PHYSICAL FINDING WAS
DEPOSITION OF COPPER AS GREEN RING
ROUND THE CORNEA AND
HEPATOMEGALY
1) WHAT IS THE PROBABLE DISEASE
2) WHAT IS THE BIOCHEMICAL
PROBLEM IN THIS DISEASE
3) WHAT IS THE TREATMENT OF THIS
DISEASE






AN ADOLESCENT INDIVIDUAL CAME TO
THE OPD WITH COMPLAINTS OF
GROWTH FAILURE, SEXUAL
IMMATURITY, LOSS OF TASTE ACUITY
AND DELAYED WOUND HEALING
1) IDENTIFY DEFICIENT MINERAL
2) WHAY IS ITS DAILY REQUIREMENT
3) NAME THE ENZYMES ASSOCIATED
WITH THIS MINERAL







A 35 YEAR OLD MAN REPORTED IN THE
HOSPITAL WITH LACK OF APPETITE,
LISTLESSNESS AND WEAKNESS OF LEGS.
HE HAD A FEELING OF HEAVINESSS AND
NUMBNESS OF LEGS WITH PINS AND
NEEDLES SENSATION. LAB
INVESTGATIONS SHOWED RAISED
PLASMA PYRUVATE LEVEL.
TRANSKETOLASE ACTIVITY IN THE RBCs
WAS LOW BUT IT SHOWED A RISE BY 40
% AFTER ADMINISTRATION OF THIAMINE
PYRO PHOSPHATE (TPP)

1) GIVE THE DIAGNOSIS
2) GIVE THE DAILY REQUIREMENT OF
THE DEFICIENT VITAMIN
3) GIVE DIETARY SOURCES OF THIS
VITAMIN
1) IDENTIFY THE INSTRUMENT
2) STATE BEERS LAW
3) STATE LAMBERTS LAW












1) DEFINE COLORIMETRY
2) STATE BEERS LAW
3) GIVE IMPORTANCE OF
COLORIMETRY