GENERIC NAME: Budesonide

BRAND NAME: Asmavent

DRUG CLASS: Beta2-Agonist, Corticosteroid, Antiasthma, Antitussive, Analgesic-Antipyretic
DRUG MECHANISM: Budesonide is an anti-inflammatory corticosteroid that exhibits potent
glucocorticoid activity and weak mineralocorticoid activity. The exact mechanism of action on
inflammation is not known. Glucocorticoids inhibit multiple cell types (e.g., mast cells, eosinophils,
neutrophils, macrophages, and lymphocytes) and mediator (e.g., histamine, eicosanoids, leukotrienes,
and cytokines) production or secretion involved in the inflammatory response. The anti-inflammatory
actions of glucocorticoids contribute to their efficacy in asthma. Budesonide decreases airway reactivity
to histamine and methacholine in hyperreactive patients.
Indications:
1. For the chronic control of signs and symptoms of bronchial asthma
2. For the maintenance treatment of asthma and as prophylactic therapy in adults and children
3. For the management of childhood croup

Contraindications:
1. Hypersensitivity to any component in the product
2. Primary treatment of status asthmaticus or other acute episodes of asthma where intensive measures
are required
DOSAGE: 250 mcg/mL (500 mcg/ 2 mL) Pulmoneb Suspension for Nebulization
ADVERSE EFFECTS: Cough, Vomiting, diarrhea, restlessness, dry mouth, nausea, throat irritation
NURSING RESPONSIBILITIES:
1. Budesonide inhalation is NOT indicated for the relief of acute bronchospasm
2. As with other inhaled medications, bronchospasm may occur with an immediate increase in
wheezing after dosing.
3. Treat bronchospasm immediately with a fast-acting bronchodilator if it occurs after dosing with
inhaled budesonide.
4. During inhalation turbuhaler must be in the upright or horizontal position
5. Advice patient to gargle with water after each dose