Unit Name: Cell Biology and Disease Unit Grade Level: 6 th Grade STAGE ONE - DESIRED RESULTS Established Learning Goals local! state or national standards" Content Statement: Cells are the funamental unit of life! Throu"h in#uir$ an %ra&ti&in" of s&ientifi& s'ills( stuent )ill unerstan essential &on&e%ts about &ells! #$ Through scienti%ic in&uiry and several activity 'riting (rom(ts! students 'ill (ractice the scienti%ic s)ills o% designing investigations! organi*ing data! analy*ing data! understanding conce(ts! recogni*ing relevant evidence! evidence and trade+o%%s! communication s)ills! organi*ing scienti%ic ideas! and grou( interactions to understand that cells are the %undamental unit o% li%e$ ,$ -tudents 'ill use their scienti%ic s)ills and their understanding o% cell biology and disease to research an assigned disease in grou(s o% t'o and (resent a .ublic -ervice /nnouncement at the end o% the unit to the rest o% the class in the %orm o% a movie! .o'er.oint! or (oster$ -ource o% the Learning Goals 0 The 1hio /cademic Content -tandards %or -cience Understandings: #$ /ll living things are com(osed o% cells$ ,$ /ll cells come %rom (ree2isting cells$ 3$ Di%%erent body tissues and organs are made o% di%%erent )inds o% cells$ 4$ /ll cells come %rom (ree2isting cells$ 5$ 6any basic %unctions o% organisms occur in cells$ 6$ Cells ta)e in nutrients and energy to (er%orm 'or)! li)e ma)ing various molecules re&uired by that cell or an organism$ 7$ Every cell is covered by a membrane that controls 'hat can enter and leave the cell$ 8$ 9ithin the cell are s(eciali*ed (arts %or the trans(ort o% materials! energy ca(ture and release! (rotein building! 'aste dis(osal! and in%ormation %eedbac)$ .redictable 6isunderstandings: #$ :% something moves it alive$ ,$ :% it ma)es light or noise it is alive$ 3$ :t is not alive unless it is doing something$ 4$ To be alive! something has to breath$ Entire UbD Unit .lan .age # o% ; Essential <uestions! e2(lanation! and rationale #$ 9hat does it mean to be alive= 9hat ty(e o% evidence do 'e need to classi%y something as >alive?= @ationale %or &uestion: This &uestion is to s(ar) in&uiry on the characteristics o% 'hat ma)es o% li%e$ -tudents 'ill learn that one o% the %undamental ans'ers to this &uestion is that all li%e is made o% cells$ ,$ :% all cells come %rom (ree2isting cells! 'here did the %irst cell come %rom= @ationale %or &uestion: This is one o% the biggest most controversial &uestions in li%e science$ Those 'ho believe in creationism use this &uestion to argue their case against those 'ho only believe in evolution$ /s)ing this &uestion and having students tal) about it 'ill s(ar) interest and curiosity into the unit$ 3$ Ho' does /((le : (ad %actory relate to the order and %unction o% a cell= @ational %or &uestion: This &uestion is meant to get students to use analogies o% cells to other things they are more %amiliar 'ith to learn the (arts o% the cell and 'hat they are res(onsible %or doing 'ithin the cell$ 4$ 9hat 'ould the 'orld be li)e! i% there 'ere no disease= 9hat diseases can 'e cure! 'hich ones 'e cannot= 9hy= @ationale %or &uestion: This &uestion is to get students thin)ing about and in&uiring about disease$ This &uestion is to s(ar) the curiosity o% 'hat is disease! 'hich ones can 'e cure or (revent and 'hich ones 'e cannot$ This is im(ortant because students need to be able to ans'er these &uestions in order to do the end o% unit (er%ormance assessment o% researching and (resenting their assigned disease$ 5$ 9hy is it im(ortant %or scientist to collect! organi*e! analy*e! inter(ret! and communicate scienti%ic data= @ationale %or &uestion: This &uestion is to get students to thin) about 'hy it is im(ortant %or them to accurately collect! analy*e! and inter(ret data that they %ind in lab activities$ -tudents 'ill be (racticing these s)ills in lab activities and is im(ortant %or them to see that they are doing 'hat real scientist do and 'hy it is im(ortant %or them to do right$ Ho' : develo(ed the essential &uestions$ : too) the goals listed belo' and tried to come u( 'ith student %riendly &uestions that 'ill s(ar) conversations and relate to the >real 'orld? as much as (ossible$ /t the end o% the %irst goal! the goal is to have students understand that cells are the %undamental unit o% li%e$ There are several di%%erent (arts to that goal$ The %irst three essential &uestions are aimed to'ard hel(ing students come to a dee(er and more com(lete understanding o% 'hat a cell is and 'hat it does$ Essential &uestion number %our %ocuses on students learning and understanding the scienti%ic s)ills that they are going to (ractice and 'hy it is im(ortant %or them to (ractice these s)ills and ho' these s)ills relate to the >real 'orld? 'or) o% scientist$ Entire UbD Unit .lan .age , o% ; Essential &uestion number %ive is meant to start the discussion o% 'hat is disease and ho' disease a%%ects the lives o% all human beings$ The students 'ill be loo)ing at disease and disease (revention throughout the unit and (resenting a researched (resentation about a disease at the end o% the unit$ 3$ Through scienti%ic in&uiry and several activity 'riting (rom(ts! students 'ill (ractice the scienti%ic s)ills o% designing investigations! organi*ing data! analy*ing data! understanding conce(ts! recogni*ing relevant evidence! evidence and trade+o%%s! communication s)ills! organi*ing scienti%ic ideas! and grou( interactions to understand that cells are the %undamental unit o% li%e$ -tudents 'ill use their scienti%ic s)ills and their understanding o% cell biology and disease to research an assigned disease in grou(s o% t'o and (resent a .ublic -ervice /nnouncement at the end o% the unit to the rest o% the class in the %orm o% a movie! .o'er.oint! or (oster$ *no)le"e -tudents 'ill )no'A -tudents 'ill )no'A #$ Bey terms+ in%ectious disease! disease! in%ectious! non+in%ectious! evidence! trade+ o%%s! carrier! e(idemiologist! vectors! &uarantine! ethics! microsco(e! %ield o% vie'! microbe! cell! cell theory! multicellular! germ theory o% disease! cell membrane! (ermeability! organelles! nucleus! nuclear membrane! chloro(lasts! cyto(lasm! mitochondria! (rotist! bacteria! viruses! red blood cells! 'hite blood cells! agar! (etri dish! immune system! antibiotics! vaccine$ -tudents 'ill be able toA #$ Develo( and test hy(otheses about the (ath o% disease transmission in a %ictional situation$ ,$ Discus societal res(onses to in%ectious disease$ 3$ Use a microsco(e to investigate li%e$ 4$ Construct a cell model and e2(lain the %unction o% cell organelles$ 5$ :nvestigate the e%%ects o% various antimicrobial solutions on the gro'th o% common bacteria$ 6$ Design an e2(eriment to reduce the number o% microbes %ound on their hands a%ter hand 'ashing$ 7$ .er%orm a role+(lay on the use o% vaccines and antibiotics in the treatment and (revention o% in%ectious disease$ 8$ 6odel the e%%ects o% antibiotics on the (o(ulation o% the disease causing bacteria during an in%ection$ @esearch a disease and (roduce a .ublic -ervice /nnouncement on the disease$ STAGE T+O - ASSESS,ENTS Performan&e Tas's #$ -tudents 'ill 'or) in grou(s o% t'o to create a .ublic -ervice /nnouncement about a (articular disease$ The .-/ 'ill be (resented orally and they 'ill also turn in a %ormal research re(ort$ They can (resent this .-/ in several 'ays$ They can create a (oster! animation! .o'er .oint! or i6ovie$ They 'ill (resent their .-/ to the class and ans'er classmate &uestions about the disease$ Entire UbD Unit .lan .age 3 o% ; This (roCect is meant to be done over time and is assigned to students at the beginning o% the unit$ :t 'ill be e2(lained to the students that they 'ill need the in%ormation they learning throughout the unit to success%ully com(lete the (roCect$ -tudents 'ill also be instructed that they 'ill need additional in%ormation that they 'ill have to %ind on their o'n using outside resources$ -tudents 'ill be given a timeline o% suggested com(letion$ ,$ Cell /nalogy$ -tudents 'ill be given the o((ortunity to 'or) in grou(s! or on their o'n to (resent a Cell /nalogy to the class that demonstrates their understanding o% the di%%erent (arts o% a cell and their %unction$ -tudents can create models or conduct a (er%ormance to demonstrate their understanding$ Other E-ien&e .ormati-e Assessments #$ Throughout the unit! students 'ill com(lete analysis &uestions and com(lete lab (rocedures that test their di%%erent scienti%ic s)ills organi*ing data! analy*ing data! designing investigations! understanding conce(ts! recogni*ing relevant evidence! evidence and trade+o%%s! communication s)ills! organi*ing scienti%ic ideas! and grou( interactions"$ :% graded! students are given a rubric and e2em(lar e2am(les to hel( guide them$ ,$ <uic) chec)s o% student understanding during classroom discussions! chec) in during lab activities! and e2it sli(s at the end o% the lesson$ 3$ Docabulary &ui**es Summati-e Assessments /t the end o% the unit! there is a summative assessment that is com(osed o% multi(le choice! short ans'er! and e2tended res(onse &uestions$ The short ans'er and e2tended res(onse &uestions are graded using the rubric o% >Understanding Conce(ts?$ This s)ill is (racticed throughout the unit and students$ STAGE T/REE - LEARNING PLAN Lesson 9HE@ET1 Begin unit lesson se&uence: 9hy is it im(ortant %or scientist to collect! organi*e! analy*e! inter(ret! and communicate scienti%ic data= These &uestions are (osed to students and told that 'e 'ill be ans'ering them as 'e 'or) through the lab activities$ A&ti-it$ 01 -tudents model the s(read o% an in%ectious disease by e2changing >saliva$? They use a >disease indicator? to %ind out i% and 'hen" they 'ere in%ected$ The class results are used to discuss the (attern o% in%ectious+disease s(read and to lay a A&ti-it$01 9+ -tudents are introduced to in%ectious disease and com(lete an >/ntici(ation Guide? on diseases$ H+ -tudents are as)ed to (lay the role o% an e(idemiologist by %iguring out 'ho started out 'ith the disease and ho' it s(read$ This lesson Entire UbD Unit .lan .age 4 o% ; %oundation %or (reventive measures$ A&ti-it$02 9hat 'ould the 'orld be li)e! i% there 'ere no disease= 9hat diseases can 'e cure! 'hich ones 'e cannot= 9hy= These essential &uestions are discussed be%ore starting the activity$ -tudents are introduced to a variety o% diseases 'ith a classroom scavenger hunt$ The class com(ares the %amiliarity 'ith various diseases among di%%erent generations studentsE vs$ (arentsE generation andFor grand(arentsE generation"$ / long+term research (roCect on disease is assigned$ -tudents eventually com(lete the (roCect by develo(ing a (ublic service announcement in the %orm o% a cartoon stri($ A&ti-it$03 -tudents build on their understanding o% disease transmission as they investigate the outbrea) o% a disease transmitted by direct human+to+human contact$ They develo( hy(otheses %or the (ath'ay o% disease transmission and then test their hy(otheses by using simulated saliva sam(les$ The conce(t o% an asym(tomatic carrier is introduced$ A&ti-it$04 -tudents 'atch a segment o% the video! A Science Odyssey: >6atters o% Li%e and Death!? that %ocuses on the bubonic (lague e(idemic in -an Grancisco in the early #;HHs$ This story becomes the basis %or investigating the relationshi( bet'een scienti%ic )no'ledge and the (revention o% disease$ is designed to hoo) the students into the overall unit o% cell biology and disease by %irst loo)ing at something they are %amiliar 'ith! disease$ E+ -tudents become engaged by 'or)ing through the activity and e2(lore ho' diseases actually s(read$ @+ -tudents com(lete a data table and re%lect and revise their inter(retation o% data$
A&ti-it$02 9+ This activity is designed to introduce students to various diseases and 'hat a >.-/? .ublic -ervice /nnouncement" is$ Due dates %or (arts o% the assignment are handed out and e2(lained$ E+ This activity is designed to e&ui( the students 'ith the basic outline o% the (er%ormance tas) they 'ill com(lete at the end o% the unit$ A&ti-it$03 H+ -tudents are hoo)ed by being (resented a scenario in 'hich they once again (lay the role o% an e(idemiologist and 'or) to %igure out the (ath o% disease transmission$ E+ -tudents 'ill use 'hat they have learned so %ar about diseases and evaluate 'hat they have learned 'hile 'or)ing through the lab activity$ @+ -tudents 'ill com(lete a data chart and com(lete analysis &uestions in 'hich they 'ill be able to rethin) big ideas and revise their 'or)$ A&ti-it$04 H+ -tudents are introduced to an actually historically event o% disease transmission and attem(t to %igure out ho' the bubonic (lague 'as s(read so &uic)ly and easily among humans$ E+-tudents are e&ui((ed 'ith the necessary real li%e e2(eriences o% disease transmission to increase their understanding o% disease and Entire UbD Unit .lan .age 5 o% ; A&ti-it$ 05 -tudents learn ho' to use a microsco(e$ A&ti-it$06 -tudents (re(are a 'et mount in order to %ind evidence o% microsco(ic li%e$ A&ti-it$ 07 9hat does it mean to be alive= 9hat ty(e o% evidence do 'e need to classi%y something as >alive?= essential &uestion is (osed to students"$ / history o% the scienti%ic discoveries leading to the germ theory o% disease is e2amined as students read! discuss! and role+(lay the contributions o% di%%erent scientists$ -cienti%ic advancements based on the germ theory! such as the use o% chemical disin%ectants! are (resented$ -tudents construct a timeline o% events %rom notes ta)en during the role (lays o% other grou( A&ti-it$ 08 -tudents observe stained Amoeba proteus cells! green (lant cells! human chee) cells! and stained and unstained onion cells under a microsco(e$ -tudents ma)e observations o% structures that are shared and that di%%er among the cells$ The im(ortance o% staining %or the visuali*ation o% cell disease transmission$ @+ -tudents com(lete grou( analysis &uestions in 'hich they rethin) big ideas! re%lect on their (rogress o% understanding about disease and disease transmission and revise their 'or) a%ter classroom discussion$ A&ti-it$ 05 9+ -tudents are introduced to a microsco(e and ho' to (ro(erly use it$ -tudents are in%ormed that they 'ill be using the microsco(e in u(coming labs and must learn ho' to use it (ro(erly in order to success%ully com(lete the lab activities$ H+ -tudents are hoo)ed in the activity by getting to use a ne' (iece o% lab e&ui(ment to loo) at various items underneath the microsco(es$ E+ -tudents are e&ui((ed 'ith the basic )no'ledge about microsco(es in order %or them to be able to use them in u(coming lab activities$ A&ti-it$ 06 H+ -tudents are using microsco(es and loo)ing %or li%e underneath the microsco(es$ E+ -tudents are e&ui((ed 'ith the basic )no'ledge o% all the di%%erent ty(es o% micro+li%e and ho' to %ind this li%e underneath the microsco(e$ A&ti-it$07 H+ -tudents are assigned grou(s and each grou( is assigned a scientist in 'hich they create a role (lay to (er%orm in %ront o% their classmates$ E+ -tudents are e&ui((ed 'ith the )no'ledge o% ho' the >Germ Theory o% Disease? has advanced throughout history$ -tudents 'al) a'ay 'ith a better understanding o% ho' medicine has advanced throughout history$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and establish ne' connections! re%lect on their (rogress so %ar in the unit and ho' things relate$ A&ti-it$08 Entire UbD Unit .lan .age 6 o% ; structures is highlighted$ A&ti-it$09 :n this activity! the idea that cells are alive and (er%orm li%e %unctions such as res(iration" is e2(lored$ -tudents are introduced to yeast as they investigate the ability o% yeast cells to res(ire$ Com(arisons o% human and yeast cells rein%orce the cellular nature o% all li%e$ A&ti-it$01: The conce(t o% the cell as a )ey biological structure is %urther investigated$ -tudents construct a sim(le cell model to investigate the %unction o% the cell membrane$ E2(erimental results demonstrate the (ermeability o% the cell membrane 'hen smaller (articles! such as those o% LugolEs solution! can cross! 'hile larger (articles! such as those o% starch! cannot$ The class discusses ho' cell (ermeability relates to cell %unctioning$ A&ti-it$011 / reading elaborates u(on the basic structures common to all cells$ The roles o% the cell membrane! cyto(lasm! and nucleus are em(hasi*ed$ The relationshi( bet'een cell biology and disease is (resented$ -tudents 'or) on cell analogy$ A&ti-it$012 -tudents begin to investigate ho' microbes are grou(ed$ -tudents vie' (re(ared slides o% (rotists 9+-tudents understand that the unit is headed to'ard the cell and 'hat ma)es u( the cell! both (lant and animal$ H+ -tudents are loo)ing at (re(ared slides underneath a microsco(e$ E+ -tudents are e&ui((ed 'ith the )no'ledge o% ho' (lant and animals cells are the same and di%%erent$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ A&ti-it$09 9+ -tudents understand that they are starting to learn the di%%erent %unctions o% a cell and ho' a cell obtains and uses energy$ H+ -tudents are creating a lab that simulates cellular res(iration$ -tudents come to understand 'hy yeast is uses in ba)ing bread and ca)es$ E+ -tudents are e&ui((ed 'ith the %undamental understand that all li%e needs energy! even at the cellular level$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ A&ti-it$ 01: 9+ -tudents develo( a basic understanding that cells are the basic unit o% all li%e$ -tudents understand the unit is no' %ocusing on 'hat organelles ma)e u( cells$ H+ -tudents are ma)ing cell models that demonstrate ho' the cell 'all is (ermeable$ E+ -tudents are e&ui((ed 'ith the )no'ledge o% ho' di%%erent cell organelles %unction together in order %or the cell to survive$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ A&ti-it$011 9+ -tudents understand ho' cells %orm tissues and tissue %orm organs$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ -tudents also com(lete a B9L chart 'ith the reading to Entire UbD Unit .lan .age 7 o% ; and bacteria to investigate some o% the characteristics o% these t'o grou(s! including si*e and the (resence or absence o% a nucleus$ A&ti-it$013 -tudents %ind out more about microbes by reading about the di%%erences among bacteria! (rotists! and viruses$ Classi%ication o% organisms is introduced as a conte2t %or the classi%ication o% microbes$ A&ti-it$ 014 / reading about (rotists! bacteria! and viruses and ho' they are classi%ied$ A&ti-it$015 -mall grou(s o% students (artici(ate in a role+(lay$ :n the %irst scene! they learn about ho' vaccinations 'or) to (rotect (eo(le against viral and bacterial illnesses$ :n the second scene! they are introduced to the use and misuse o% antibiotics$ A&ti-it$016 -tudents learn ho' 'as the %irst antibiotic discovered$ -tudents e2(lore the (roblems encountered in testing and (roducing this >miracle drug?= -tudents vie' historic %ootage and (hotogra(hs that hel( bring alive the climate o% the time and the (ersonalities involved$ A&ti-it$017 -tudents model the e%%ects o% antibiotics on the (o(ulation o% the disease+causing bacteria during an in%ection$ -tudents toss number cubes to determine 'hether an >in%ected (atient? remembers to ta)e the (rescribed daily dose o% antibiotics! 'hich in turn re%lect on and evaluate their level o% understanding$ A&ti-it$012 9+ -tudents begin to learn some o% the di%%erences among the cells o% t'o grou(s o% microbes those 'ith a nucleus and those 'ithout" H+ -tudents are using microsco(es to conduct the investigation$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ -tudents create a Denn Diagram com(aring .rotist! Bacteria! and Human Cells$ A&ti-it$013 9+ -tudents begin to learn ho' microbes %it into the classi%ication o% organisms$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ -tudents create a Denn Diagram o% .rotist! Bacteria! and Diruses$ A&ti-it$014 E+ -tudents are e&ui((ed 'ith the basic )no'ledge about (rotists! bacteria! and viruses and ho' they are classi%ied$ A&ti-it$015 9+ -tudents develo( and understanding o% ho' vaccines (revent disease$ H+ -tudents are (er%orming a role+(lay to learn the content in the lesson$ A&ti-it$016 9+ -tudents learn ho' the %irst antibiotic 'as discovered and ho' antibiotics are used to treat bacterial in%ections$ @+ -tudents 'atch the video and re%lect on the im(act o% (enicillin in society$ Entire UbD Unit .lan .age 8 o% ; a%%ects the si*e o% the bacterial (o(ulation in the (atient$ The results demonstrate that it is critical to remember to ta)e each dose on time and to com(lete the entire (rescribed course o% antibiotics$ A&ti-it$018 This e(idemiological scenario allo's students to a((ly 'hat they have learned about disease and disease transmission in a board game$ The game is closely based on an actual emerging disease$ -tudents gather data by (laying the game and then modi%y their hy(otheses in light o% ne' evidence$ By )no'ing the method o% transmission! students design (ublic health measures to save the 'orld %rom >6aracondo Gever$? Performan&e Pro;e&t E<am =Communi&ation S'ills( Grou% Intera&tion( Unerstanin" Con&e%ts( Or"ani>in" S&ientifi& Ieas an Desi"nin" In-esti"ations: -tudents (resent .-/ (roCects Summati-e E<am =Unerstanin" Con&e%ts an Or"ani>in" S&ientifi& Ieas?: -tudents ta)e multi(le choice! short ans'er! and e2tended res(onse e2am$ A&ti-it$017 H+ -tudents are 'or)ing on a hands on activity that models the e%%ects o% antibiotics on the (o(ulation o% the disease+causing bacteria during an in%ection$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ A&ti-it$018 9+ -tudents see ho' everything ties together throughout the unit! 'hile 'ra((ing u( the unit$ H+ -tudents are (laying a board game that 'ra(s u( the unit and a((ly all that they have learned throughout the unit$ E+ -tudents are e&ui((ed and revie' all conce(ts covered throughout the unit 'hile (laying the board game$ @+ Through analysis &uestions at the end o% the lesson! students rethin) big ideas and re%lect on their (rogress through the unit$ Entire UbD Unit .lan .age ; o% ;
(Models and Modeling in Science Education 4) John K. Gilbert, David F. Treagust (Auth.), Prof. John K. Gilbert, Prof. David Treagust (Eds.)-Multiple Representations in Chemical Education-Springer Neth (Recovered)