Yasna Molina Guajardo

Homo sapiens human toll-like receptor 4 (TLR4) gene, TLR4B allele, partial cds
GenBank: AF177766.1
FASTA Graphics PopSet Go to: LOCUS 1999 DEFINITION allele, partial cds. ACCESSION VERSION KEYWORDS SOURCE ORGANISM AF177766 AF177766.1 . Homo sapiens (human) Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE AUTHORS TITLE JOURNAL REFERENCE AUTHORS TITLE JOURNAL University 1 (bases 1 to 2576) Poltorak,A., Smirnova,I. and Beutler,B. Genetic variation at the TLR4 locus Unpublished 2 (bases 1 to 2576) Poltorak,A., Smirnova,I. and Beutler,B. Direct Submission Submitted (17-AUG-1999) Department of Internal Medicine, GI:6403466 Homo sapiens human toll-like receptor 4 (TLR4) gene, TLR4B AF177766 2576 bp DNA linear PRI 13-NOV-

of Texas, Southwestern Medical Center and the Howard Hughes Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75235-9050, USA FEATURES source Location/Qualifiers 1..2576 /organism="Homo sapiens" /mol_type="genomic DNA" /db_xref="taxon:9606" /map="9q32-q34" gene <1..2576 /gene="TLR4" /allele="TLR4B" /experiment="experimental evidence, no additional details recorded" /note="most common coding variant of TLR4" intron <1..59 /gene="TLR4" /allele="TLR4B" /experiment="experimental evidence, no additional details recorded" /number=2 exon 60..2576 /gene="TLR4" /allele="TLR4B" /number=3 mRNA <61..2576 /gene="TLR4" /allele="TLR4B" /product="TLR4-B" CDS <61..2319 /gene="TLR4" /allele="TLR4B" /experiment="experimental evidence, no additional details recorded" /codon_start=1 /product="human toll-like receptor 4" /protein_id="AAF07823.1" /db_xref="GI:6403467"

/translation="CEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKL VAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQS IYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCI QGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDGIIDLFN CLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKG GNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTISLKYLDLSFNGVITMSSNFLGL EQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMA GNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDT FPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIK DQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYK FYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRD FIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFI VLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTV GTGCNWQEATSI"

Smbolos:

Intrn Exn CDS

ORIGIN 1 61 121 181 241 301 361 421 481 tattttaggt tgtgaaatcc atattgacag ttacagaagc catctcaaaa cctgagtatt caaagtattt ttagacctgt cttcataagc tcttattcag agacaattga gaaaccccat tggtggctgt ctttgaaaga tttctaatct attgcacaga ccctgaaccc tgactttaag cagaaatatt agatggggca ccagagttta ggagacaaat acttaatgtg gaccaatcta cttgcgggtt tatgaacttt aaataatttt agataatcaa tatcagagcc gccctgggag ctagcatctc gctcacaatc gagcacttgg ctacatcaaa atccaaccag gatagtttaa tgtcttttta taagccacct ccttttctgg tagagaactt ttatccaatc acctttccag tgcccctact gtgcatttaa atgtaatgaa ttcctgtagg ctctacctta actatcaagt ccccattgga tttcaaatta caacaagatt caatctctct agaaattagg aacttgtatt

541 601 661 721 781 841 901 961 1021 1081 1141 1201 1261 1321 1381 1441 1501 1561 1621 1681 1741 1801 1861 1921 1981 2041 2101 2161 2221 2281 2341 2401 2461 2521

caaggtctgg aacttggaaa ttccgattag acaaatgttt tataatttcg ttgaaactca tcagaagttg aaaggttgct ttcaatggtg gatttccagc aacctcattt aatggcttgt cttccagata ctggagcagt agccacaaca gttcttgatt ccaagtagtc cagagtttcc gaatgtgcaa cagatgaata gcagttctgg ggtagaggtg gtaaggaatg cactacagag cataaaagcc atctttgaat ttcattgtcc cttctcagca tggagacgac ggtacaggat tgaggcattt ccacatgtca tgctaatctc ttccaggtgg

ctggtttaga agtttgacaa catacttaga cttcattttc gatggcaaca aatctctcaa atctaccaag gttctcaaag ttattaccat attccaattt accttgacat ccagtctcga tcttcacaga tgtctccaac acttcttttc acagtctcaa tagctttctt tgcaatggat caccttcaga agaccatcat tctataagtt aaaacatcta agctagtaaa actttattcc gaaaggtgat atgagattgc tgcagaaggt ggaacactta tcagaaaagc gcaattggca cttgcccagc ggccttatgc aaggagcttc gcatttcaac

agtccatcgt atctgctcta ctactacctc cctggtgagt tttagaatta aaggcttact ccttgagttt tgattttggg gagttcaaac gaaacaaatg ttctcatact agtcttgaaa gctgagaaac agcatttaac attggatacg tcacataatg aaatcttact caaggaccag taagcagggc tggtgtgtcg ctattttcac tgatgccttt gaatttagaa cggtgtggcc tgttgtggtg tcagacctgg ggagaagacc cctggagtgg cctgctggat ggaagcaaca tgggtccaac taagggtgag cagtgcagag caactcagtc

ttggttctgg gagggcctgt gatggtatta gtgactattg gttaactgta ttcacttcca ctagatctca acaatcagcc ttcttgggct agtgagtttt cacaccagag atggctggca ttgaccttcc tcactctcca tttccttata acttccaaaa cagaatgact aggcagctct atgcctgtgc gtcctcagtg ctgatgcttc gttatctact gaaggggtgc attgctgcca tcccagcact cagtttctga ctgctcaggc gaggacagtg ggtaaatcat tctatctgaa acttgttcag taattccatg ggaataaatg aaggaaccca

gagaatttag gcaatttgac ttgacttatt aaagggtaaa aatttggaca acaaaggtgg gtagaaatgg taaagtattt tagaacaact cagtattcct ttgctttcaa attctttcca tggacctctc gtcttcaggt agtgtctgaa aacaggaact ttgcttgtac tggtggaagt tgagtttgaa tgcttgtagt ttgctggctg caagccagga ctccatttca acatcatcca tcatccagag gcagtcgtgc agcaggtgga tcctggggcg ggaatccaga gaggaaaaat ttaataagta gtgcactaga ctagactaaa tgacaaagaa

aaatgaagga cattgaagaa taattgtttg agacttttct gtttcccaca gaatgctttt cttgagtttc agatctgagc agaacatctg atcactcaga tggcatcttc ggaaaacttc tcagtgtcaa actaaatatg ctccctccag acagcatttt ttgtgaacac tgaacgaatg tatcacctgt atctgttgta cataaagtat tgaggactgg gctctgcctt tgaaggtttc ccgctggtgt tggtatcatc gctgtaccgc gcacatcttc aggaacagtg aaaaacctcc ttaaatgctg tatgcagggc atacagagtc agtcat