Toxidromes

Toxidrome Presentation Vital Sign Changes Causative

Agents
Anticholinergic Delirium, Flushed Skin, Tachycardia Antihistamines
Dilated Pupils, Urinary Hyperthermia Scopolamine
Retention, Decreased Hypertension Jimson Weed
Bowel Sounds, Memory Angel Trumpet
Loss, Seizures Benztropine
Hot as a Hare, Dry as a Tricyclic Anti-
Bone, Red as a Beet, Blind Depressants
as a Bat
Atropine
Cholinergic Confusion, Weakness, Bradycardia Organophosphates
Salivation, Lacrimation, Hypothermia Carbamates
Defecation, Emesis, Tachypnea Mushrooms
Diaphoresis, Muscle
Fasciculations, Miosis,
Seizures
Hallucinogenic Disorientation, Tachycardia Amphetamines
Hallucinations, Visual Tachypnea Cannabinoids
Illusions, Panic Hypertension Cocaine
Reaction, Moist Skin, Phencyclidine
Hyperactive Bowel (PCP)
Sounds, Seizures
Opiate/Narcotic Altered Mental Status, Shallow Respirations Opiates
Unresponsiveness, Slow Respiratory Rate Propoxyphene
Miosis, Shock Bradycardia Dextromethorphan
Hypothermia
Hypotension
Sedative/Hypnotic Coma, Stupor, Apnea Barbiturates
Confusion, Sedation, Benzodiazepines
Progressive Ethanol
Deterioration of CNS Anticonvulsants
Function
Sympathomimetic Delusions, Paranoia, Tachycardia Cocaine
Diaphoresis, Bradycardia (if pure Amphetamines
Piloerection, Mydriasis, alpha agonist) Methamphetamine
Hyperreflexia, Seizures, Hypertension Phenylpropano-
Anxiety Lamine
Ephedrine
Pseudoephedrine
Albuterol
Ma huang