Drug Caleuitions & ug Adminstration What IS Dopamine? Dopamine (Incopin, Dopastat, Revimine) isan IV injectable medication that produces fees associated with the stimulation ofthe sympathetic nervoussyscem (sympathomimeticagene). Dopamine causes renal, mesen- teri and cerebral artery vatodilation (i, a dopaminergic effet) in drug, dosages les chan 3 meg/kgimin. In moderate dosages, beeween 3 and 10 meg/kg/min, i improves blood pressure (BP) in nodhypovoleric states of shock. In higher dosages (above 10 meglkg/mnin), dopamine ‘causes the release of norepinephrine and stimulates alpha receptors, ‘There are cwo main reasons thet you need to monitor patients receiving dopamine 1, Sudden increases in BP can cas in the brain, myocardial infu ‘ooring of surgical and bone marrow aspiration sites, oozing of vascular suture lines, and aortic aneutysi oozing if 4 | dents (CVA) tear, increased I}Drug Caleiione& Drug Adisbin _ ‘Thre wep cn be wed calculate the dose of dopamine rom the ow et: ‘Sep 1: Deter the dove pr hon, ‘Siap 2: Convert wiligams to microg. ‘Step 3: Conver microgramslhour to miropramslninut EXAMPLE: You have 500 mL D,W to which you add 400 mg of opamine. This io infest 400 meg/nin IV. ‘What ie the low ret Stop 114500 xefin x 60 i= 24,000 ingfbe ‘Step 2:24,000 mega = 24 mgr ‘Step 3:400 mg: 800 eal.» 24g. “Anse « 30 ml ele EXAMPLE: You have $00 mL D,W plas 800 mg dopemine at 25 male LV. Whats the dose? Step 11800 mg. 500 es. gs 25 = 0 mle ‘Step 2:40 hr = 40,000 megs ‘Step 340,000 meer 60 min 656.6 Asie: 667 mein (ounded up fom 666.8) our stp can be uted to cleat che Bow ite fam the dow of Aoparsine pr klogram of patient weight: ‘Stop 1s Calle the don et nn. ‘Susp 2s Clelt the dae pe ho, ‘Step 3+ Convert ike unis. ‘Step 4: Caeser per our ow ete EXAMPLE: You have dopamine prescribed a 10 mcgky/min. You have 0250 ml. bag of DW with 400 mgoF “cio tr ee Wh Shenae Sup 120 ip 8 ea a Sipaeroncgniencinm= 000mm Gf ‘Seep 3:48,000 mcg = 48 gb ‘Step 4:40 ng 250 el. 48mg. “Anse: x= 30 mtd (ein)