ABTRACT THE RELATIONSHIP BETWEEN HEMATOCRIT AND THROMBOCYTE IN DENGUE HEMORRHAGIC FEVER AT RSUP PROF. DR. R. D.

KANDOU MANADO Hukom AO, Warouw SM, Memah MF, Mongan AE Clinical Pathology Medical Faculty Sam Ratulangi University, Manado

Background: Dengue hemorrhagic fever (DHF) has been an international problem especially for children. Two main pathophysiological changes occur in dengue hemorrhagic fever. First one is an increased vascular permeability and the second one is disorder of haemostasis Hematocrit and thrombocyte are laboratory parameters that needed to monitoring development of DHF. Methods: A retrospective cross sectional study. Samples are patients that diagnosed with dengue hemorrhagic fever in RSUP Prof. Dr. R. D. Kandou Manado in 2012. Criterias include are patients < 15 years old and diagnosed based from WHO 1997, in this case already tested with hematocrit test and platelet count. This research use medical record and for the statistical analysis use t test also spearmans correlation test. Result: There were 137 children with dengue hemorrhagic fever and 62 children become the sample. There is no significance relationship between hematocrit and thrombocyte in dengue hemorrhagic fever patients (p=0,133). Conclusion: In dengue hemorrhagic fever children patients, there is no significance relationship between hematocrit and thrombocyte. Keywords: dengue hemorrhagic fever, hematocrit, thrombocyte

ii