Figure 1 Clinical, histochemical and immunohistochemical findings before and aft er narrow-band UVB phototherapy in a vitiligo patient.

Negative and positive tyr osinase (A, B), HMB45 (C, D) and Masson-Fontana (E, F) staining before (A, C, E) and after (B, D, F) therapy; lesion appearance before (G) and after (H) therapy . Histology: vitiligo, 10x, H&E. Note that tissue appears normal. Histology: vitiligo, 10x, stained for melanin. Note that melanin (tiny, dark spo ts) is absent on the basal layer of the epidermis although it is preserved aroun d the hair follicle.