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Vessel due F is an anticoagulant used to treat various vascular conditions and diseases. It works by inhibiting coagulation through several mechanisms including augmenting the activity of antithrombin III. This allows it to inactivate several coagulation factors and prevent thrombin formation. It is dosed either as 1 capsule twice daily for 60-90 days or 1 ampule daily for 10-20 days followed by the capsule dosage, depending on if it is for an acute or chronic condition. Nurses should monitor for signs of bleeding or hemorrhage and hypersensitivity reactions and check platelet counts regularly during treatment.
Vessel due F is an anticoagulant used to treat various vascular conditions and diseases. It works by inhibiting coagulation through several mechanisms including augmenting the activity of antithrombin III. This allows it to inactivate several coagulation factors and prevent thrombin formation. It is dosed either as 1 capsule twice daily for 60-90 days or 1 ampule daily for 10-20 days followed by the capsule dosage, depending on if it is for an acute or chronic condition. Nurses should monitor for signs of bleeding or hemorrhage and hypersensitivity reactions and check platelet counts regularly during treatment.
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Vessel due F is an anticoagulant used to treat various vascular conditions and diseases. It works by inhibiting coagulation through several mechanisms including augmenting the activity of antithrombin III. This allows it to inactivate several coagulation factors and prevent thrombin formation. It is dosed either as 1 capsule twice daily for 60-90 days or 1 ampule daily for 10-20 days followed by the capsule dosage, depending on if it is for an acute or chronic condition. Nurses should monitor for signs of bleeding or hemorrhage and hypersensitivity reactions and check platelet counts regularly during treatment.
Copyright:
Attribution Non-Commercial (BY-NC)
Formati disponibili
Scarica in formato DOC, PDF, TXT o leggi online su Scribd
Indication: Vascular pathologies w/ thrombotic risk, transient ischemic attacks & cerebrovascular disease, peripheral vascular insufficiency, diabetic retinopathy, MI, retinal vasal thrombosis. Mechanism of action: Inhibits coagulation by attacking several sites of the coagulation system. Its effect is dependent on the presence of antithrombin III, an alpha 2- globulin whose activity is augmented by heparin. The heparin- antithrombin complex inactivates factors IXa, Xa, XIa and XIIa, and prevents thrombin formation. Furthermore, the complex reverses the effect of already formed thrombin. In high concentrations, heparin also inhibits thrombocyte aggregation. Drug Classification: Anticoagulant, antithrombotics & fibrinolytics Dosage: Acute cases 1 amp 10-20 days once daily followed by 1-2 cap bid 30 mins before meals for 60-90 days. Chronic cases1-2 cap bid 30 mins before meals for 60-90 days. Special Precaution: Periodically monitor parameters. Pregnancy. Pregnancy Risk Category: (not yet applicable); Heparin: C Adverse Reaction: Cap GI disorders: nausea, vomiting, epigastralgia. Amp Pain, burn, hematoma at the site of injection. Contraindication: Hypersensitivity to sulodexide, heparin & heparin- like products. Diathesis & hemorrhagic diseases. Form: Capsule- 250 LSU; Ampule- 300 LSUx2 mL Nursing Responsibilities: Assess patients for signs of bleeding and hemorrhage (bleeding gums; nosebleed; unusual bruising; black, tarry stools; hematuria; fall in hematocrit or blood pressure; guaiac- positive stools). Notify physician if these occur. Monitor patient for hypersensitivity reactions (chills, fever, urticaria). Report signs to physician Subcutaneous: observe injection sites for hematomas, ecchymosis, or inflammation. Monitor platelet count every 2-3 days throughout therapy. May cause mild thrombocytopenia, which appears on the 4th day and resolves despite continued heparin therapy.