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Units
1 gram (g) = 1000 miligrams(mg) 1 mg = 1000 micrograms(microg) 1 microgram = 1000 nanograms (nanog)
Standard formula
What you want x What its in What youve got All of the values must be in the same unit of measure e.g. mg, mls, hour
150mg phenytoin is prescribed (what you want) you have 250mg (what youve got) in 5 ml (what its in) 150 x 5 = 3ml is the volume you need to give 250
Rates to dosages
1. Convert to same unit of measure
Divide by the volume of diluent Multiply by the rate
1.
I have x microgram
2.
2.
I have y microgram/ml
3.
3. 4. 5.
4.
5.
Example
Adrenaline 10mg in 100ml running at 4ml/hr in a 70 kg patient. How many microg/kg/min is the patient getting?
1.
2. 3. 4. 5.
Doses to rates
Amount of drug required x weight x (60) Divided by microgram/ml of drug = ml/hr
Example 2
Patient of 70kg prescribed adrenaline at 0.2 microgram/kg/min. 0.2 x 70 x 60 = 840 microg/hr = what you want 10mg in 100ml = 100 microg/ml = what youve got What you want = What youve got 840 100 = 8.4 ml/hr