CNS Pharmacology I - vivas 2010/1: Describe how phenytoin is administered in status epilepticus? Describe t he adverse effects phenytoin.

2010/1: Describe the pharmacokinetics of atropine. At which receptors does atrop ine act? What are the effects of atropine on heart rate? 2009/2: Describe the pharmacokinetics of propofol. What are the side-effects of propofol? 2009/2: How does ketamine affect the cardiovascular system? What are the side ef fects of ketamine? 2009/2: Describe the mechanism of action of suxamethonium. What are the side eff ects of suxamethonium? 2009/2: What is the mechanism of action of local anaesthetics? Which local anaes thetics are used topically? 2009/1: Describe the mechanism of action of carbamazepine. How is carbamazepine metabolised? What is the effect of the metabolism of other drugs? 2008/2: Describe the pharmacokinetics of phenytoin. Describe the pharmacodynamic s of phenytoin. 2008/1: Describe the pharmacokinetics of thiopentone. What adverse effects does it cause when used as an anaesthetic induction agent? 2008/1: What is the mechanism of action of atropine? What are the toxic effects of atropine? What are the therapeutic uses for atropine? 2007/2: Why is levodopa used in combination with carbidopa? What are the adverse effects of levodopa? 2007/1: What is the mechanism of action of prilocaine? Describe the adverse effe cts of prilocaine. How is prilocaine metabolized? 2007/1: What is the mechanism of action of atropine? Give examples of organ effe cts. What are the features of atropine poisoning? 2006/2: What types of anaesthesia does ketamine produce? Which receptor action p roduces the anaesthesia? What are the cardiorespiratory effects of ketamine? 2006/2: What is benztropine? What are the adverse effects of benztropine? 2006/1: Describe succinylcholine and its metabolism. What are the adverse effect s of depolarising neuromuscular blockade? 2006/1: What are the organ effects of nitrous oxide? What is the mechanism of ac tion of nitrous oxide? Are there any other mechanisms by which nitrous oxide wor ks? 2006/1: What is the mechanism of action of local anaesthetics? How are local ana esthetics classified? Give an example of each group. Describe the ideal local an aesthetic for topical application. 2005/1: Describe the mechanism of action of sodium valproate. What potential dru g interactions can occur with sodium valproate? 2005/1: What are the effects of nitric oxide? What are the potential therapeutic applications of nitric oxide? 2005/1: What are the pharmacodynamic effects of lignocaine on the heart? What fe atures distinguish lignocaine from other Class I antiarrhythmics? What are the c linical uses of lignocaine? 2004/2: Explain the chemical classification of local anaesthetics. Explain tachy phylaxis associated with local anaesthetic use. 2004/2: Describe the mechanism of action of lignocaine on the heart. Describe th e adverse effects of lignocaine. 2003/1: Describe the pharmacokinetics of propofol. What are the adverse effects of propofol? 2003/1: What are the pharmacokinetics of suxamethonium? What are the adverse eff ects of suxamethonium?