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Hypopituitarism, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
Hypopituitarism, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
Hypopituitarism, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
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Hypopituitarism, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions

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Hypopituitarism is a medical disorder in which the pituitary gland does not normally produce usual amounts of some or all of its eight hormones.
Hypopituitarism is due to an inadequate production of hypothalamic-releasing hormones or due to an inability of the pituitary gland to secrete hormones.
Hypopituitarism is typically chronic and lifelong unless successful surgery or medicinal therapy of the underlying cause can restore pituitary function.
Causes
In hypopituitarism, there is a loss or decrease of one or more pituitary hormones.
Decrease of a hormone results in loss of function in the gland and the hormonal regulation.
Loss of TSH results in loss of function of the thyroid gland.
1.Brain surgery
2.Brain tumor
3.Head trauma
4.Infections or inflammation of the brain and the tissues that support the brain
5.Radiation therapy
6.Stroke
Sometimes, hypopituitarism is due to abnormal immune system or metabolic diseases, such as:
1. Hemochromatosis
2. Histiocytosis X
Symptoms
The patient presents with endocrine dysfunction:
A.Adrenocorticotrophic hormone (ACTH) deficiency:
1.Chronic: fatigue, pallor, anorexia, weight loss.
2.Acute: weakness, dizziness, nausea, vomiting, fever, shock.
3.Children: delayed puberty, failure to thrive.
4.Hypoglycemia, hypotension, anemia, lymphocytosis, hyponatremia.
B.Thyroid-stimulating hormone (TSH) deficiency:
1.Tiredness, cold intolerance, constipation, hair loss, dry skin, cognitive slowing.
2.Weight gain, bradycardia, hypotension.
3.Children: delayed development, growth restriction, intellectual impairment.
C Gonadotrophin deficiency:
1.Women: oligomenorrhea, loss of libido, dyspareunia, infertility, osteoporosis.
2.Men: loss of libido, loss of facial, scrotal, and body hair, mood impairment, reduced muscle mass, osteoporosis, anemia.
3.Children: delayed puberty.
D.Growth hormone deficiency:
1.Reduced muscle mass and strength, visceral obesity, impairment of attention, memory.
2.Dyslipidemia, premature atherosclerosis.
3.Children: growth restriction.
E.Antidiuretic hormone deficiency:
1.Polyuria, polydipsia.
2.Reduced urine osmolality, hypernatremia.
3.May also present with features due to the underlying cause:
a.Space-occupying lesion: headaches or visual field deficits.
b.Large lesions affecting the hypothalamus: polydipsia and inadequate secretion.
Diagnosis:
To diagnose hypopituitarism, there must be low hormonal amounts from the pituitary gland.
1.Serum ACTH
2.Serum cortisol
3.Serum estradiol
4.Serum follicle stimulating hormone
5.Serum insulin-like growth factor 1
6.Serum luteinizing hormone
7.Serum testosterone level
8.Serum thyroid stimulating hormone
9.Thyroid hormone
10.Brain CT scan
11.Pituitary MRI
Treatment
Acute resuscitation, such as intravenous fluids, may be needed
If hypopituitarism has been caused by a tumor, pituitary function may be returned to normal after successful surgical or medical removal of the lesion.
Surgical:
In pituitary stroke or coma, immediate operative decompression may be life-saving.
Removal of macroadenomas may be needed if they do not respond to medical therapy.
If hypopituitarism is caused by a tumor, you may require surgery to excise the tumor.
Radiation therapy may also be needed
Medical care consists of hormone replacement as appropriate and treatment of the underlying cause.
The patient will need lifelong hormone medicines to replace hormones that are no longer made by glands under the regulation of hormones from the pituitary gland.
1.Corticosteroids (cortisol)
2.Growth hormone
3.Sex hormones (testosterone for men and estrogen for women)
4.Thyroid hormone

TABLE OF CONTENT
Introduction
Chapter 1 Hypopituitarism
Chapter 2 Causes
Chapter 3 Symptoms
Chapter 4 D

LanguageEnglish
PublisherKenneth Kee
Release dateApr 17, 2018
ISBN9781370212897
Hypopituitarism, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions
Author

Kenneth Kee

Medical doctor since 1972.Started Kee Clinic in 1974 at 15 Holland Dr #03-102, relocated to 36 Holland Dr #01-10 in 2009.Did my M.Sc (Health Management ) in 1991 and Ph.D (Healthcare Administration) in 1993.Dr Kenneth Kee is still working as a family doctor at the age of 74However he has reduced his consultation hours to 3 hours in the morning and 2 hours inthe afternoon.He first started writing free blogs on medical disorders seen in the clinic in 2007 on http://kennethkee.blogspot.com.His purpose in writing these simple guides was for the health education of his patients which is also his dissertation for his Ph.D (Healthcare Administration). He then wrote an autobiography account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.comThis autobiography account “A Family Doctor’s Tale” was combined with his early “A Simple Guide to Medical Disorders” into a new Wordpress Blog “A Family Doctor’s Tale” on http://ken-med.com.From which many free articles from the blog was taken and put together into 1000 eBooks.He apologized for typos and spelling mistakes in his earlier books.He will endeavor to improve the writing in futures.Some people have complained that the simple guides are too simple.For their information they are made simple in order to educate the patients.The later books go into more details of medical disorders.He has published 1000 eBooks on various subjects on health, 1 autobiography of his medical journey, another on the autobiography of a Cancer survivor, 2 children stories and one how to study for his nephew and grand-daughter.The purpose of these simple guides is to educate patient on health disorders and not meant as textbooks.He does not do any night duty since 2000 ever since Dr Tan had his second stroke.His clinic is now relocated to the Buona Vista Community Centre.The 2 units of his original clinic are being demolished to make way for a new Shopping Mall.He is now doing some blogging and internet surfing (bulletin boards since the 1980's) startingwith the Apple computer and going to PC.The entire PC is upgraded by himself from XT to the present Pentium duo core.The present Intel i7 CPU is out of reach at the moment because the CPU is still expensive.He is also into DIY changing his own toilet cistern and other electric appliance.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"

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    Book preview

    Hypopituitarism, A Simple Guide To The Condition, Diagnosis, Treatment And Related Conditions - Kenneth Kee

    Hypopituitarism,

    A

    Simple

    Guide

    To

    The Condition,

    Diagnosis,

    Treatment

    And

    Related Conditions

    By

    Dr Kenneth Kee

    M.B.,B.S. (Singapore)

    Ph.D (Healthcare Administration)

    Copyright Kenneth Kee 2015 Smashwords Edition

    Published by Kenneth Kee at Smashwords.com

    Dedication

    This book is dedicated

    To my wife Dorothy

    And my children

    Carolyn, Grace

    And Kelvin

    This book describes the Hypopituitarism, Diagnosis, Treatment and Related Conditions or in vernacular terms

    (What You need to treat Hypopituitarism)

    This eBook is licensed for the personal enjoyment only. This eBook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each reader.

    If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy.

    Thank you for respecting the hard work of this author.

    Introduction

    I have been writing medical articles for my blog http://kennethkee.blogspot.com (A Simple Guide to Medical Condition) for the benefit of my patients since 2007.

    My purpose in writing these simple guides was for the health education of my patients.

    Health Education was also my dissertation for my Ph.D (Healthcare Administration).

    I then wrote an autobiolographical account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.com.

    This autobiolographical account A Family Doctor’s Tale was combined with my early A Simple Guide to Medical Conditions into a new Wordpress Blog A Family Doctor’s Tale on http://ken-med.com.

    From which many free articles from the blog was taken and put together into 600 eBooks.

    Some people have complained that the simple guides are too simple.

    For their information they are made simple in order to educate the patients.

    The later books go into more details of medical conditions.

    The first chapter is always from my earlier blogs which unfortunately tends to have typos and spelling mistakes.

    Since 2013, I have tried to improve my spelling and writing.

    As I tried to bring you the latest information about a condition or illness by reading the latest journals both online and offline, I find that I am learning more and improving on my own medical knowledge in diagnosis and treatment for my patients.

    Just by writing all these simple guides I find that I have learned a lot from your reviews (good or bad), criticism and advice.

    I am sorry for the repetitions in these simple guides as the second chapters onwards have new information as compared to my first chapter taken from my blog.

    I also find repetition definitely help me and maybe some readers to remember the facts in the books more easily.

    I apologize if these repetitions are irritating to some readers.

    Chapter 1

    Hypopituitarism

    What is Hypopituitarism?

    Hypopituitarism is a medical disorder in which the pituitary gland does not normally produce usual amounts of some or all of its eight hormones.

    Hypopituitarism is due to an inadequate production of hypothalamic-releasing hormones or due to an inability of the pituitary gland to secrete hormones.

    Symptoms are dependent on the amount of hormone reduction and the sudden onset.

    Hypopituitarism is normally a mixture of eight hormonal deficiencies but rarely affects every pituitary hormone.

    Hypopituitarism is typically chronic and lifelong unless successful surgery or medicinal therapy of the underlying condition can restore pituitary function.

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