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    Epigenetic Feeding
    Epigenetic Feeding
    Epigenetic Feeding
    Ebook51 pages33 minutes

    Epigenetic Feeding

    By Carlos Herrero Carcedo

    ()

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    About this ebook

    Diets rich in fat and sugar, as well as obesity, are associated with changes in the usual patterns of DNA methylation in genes involved in energetic homeostasis of the liver.
    There are innumerable nutritional factors that induce important epigenetic modifications that can cause the establishment of the disease or the protection of the organism against it.

    LanguageEnglish
    PublisherCarlos Herrero Carcedo
    Release dateMay 23, 2017
    Epigenetic Feeding
    Author

    Carlos Herrero Carcedo

    Autor de dos Libros con tapa: Manual Básico de Farmacología y 200 Ideas para Mejorar la Rentabilidad de tu Farmacia, una publicación en la revista Alimentación, Equipos y Tecnología: La histamina en las distintas etapas de fabricación de conservas de atún y seis Ebooks: Disruptores Endocrinos, La Salud no es un Negocio, Obesidad Infantil. Rista. Respuesta Insuficientemente Adecuada, Vivir sin Cáncer, Ser Mayor sin Edad y Predisposición a Ser Homosexual.Posee tres licenciaturas (Farmacia, Ciencias Químicas, Ciencia y Tecnología de los Alimentos) y experiencia en los departamentos de Calidad, Producción y Ventas.

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      Book preview

      Epigenetic Feeding - Carlos Herrero Carcedo

      EPIGENETIC

      FEEDING

      Carlos Herrero Carcedo

      www.carlosherrerocarcedo.com

      EPIGENETIC

      FEEDING

      Carlos Herrero Carcedo

      www.carlosherrerocarcedo.com

      Copyright© 2020 by Carlos Herrero Carcedo

      All rights reserved

      LEGAL WARNING

      It is strictly prohibited without the written permission of the copyright holder, the reproduction of this work by any means or process including reprography and computer processing.

      TABLE OF CONTENTS

      1. EPIGENETICS

      2. EPIGENETICS AND DISEASES

      3. METHYL-GROUP DONORS

      4. EARLY NUTRITION

      5. FAST FOOD

      6. EPIGENETIC FEEDING

      7. ENDOCRINE DISRUPTORS

      8. ABBREVIATIONS

      1. EPIGENETICS

      Our body consists of 30 trillion cells, 30 million million, all with the same genome. At the core of each human somatic cell are 23 pairs of chromosomes containing the genetic information. Each chromosome is a DNA molecule of about two meters long, associated with RNA and proteins.

      DNA is a polymer of nucleotides, which are composed of three different substances: phosphoric acid, a monosaccharide of the pentose type (deoxyribose) and a cyclic nitrogenous base that can be purine (adenine or cytosine) or pyrimidine (thymine or guanine). The two long nucleotide strands, in helical form, are held together by the bonds between the nitrogen bases of both helices, only adenine is linked with thymine and cytosine with guanine. DNA genetic information resides in the sequence of the nitrogenous bases in the nucleotide chain.

      Each chromosome is the result of different levels of compaction of the DNA double helix. At a first level, the DNA binds with the structural proteins called histones (H1, H2A, H2B, H3 and H4). Some 146-200 base pairs of DNA are wound around an octamer of histones (two H3, two H4 and two dimers H2A/H2B) and on this complex the histone H1, in charge to seal the two turns of the DNA, being called to the resulting structure the nucleosome. These nucleosomes are repeated forming a structure of DNA type necklace or string of beads. At the next level of compaction, the nucleosome chain is coiled into a solenoid. Likewise, this solenoid is folded to form the chromatin fiber, which in turn is compacted into new loops. Finally, a new degree of compaction will result in a dense package of chromatin, forming the arms of the chromosomes.

      Genes are dispersed linear sequences of nucleotides found in the DNA molecule and encoding the necessary instructions for protein synthesis. The DNA contains 25,000 genes that direct all cellular metabolic activities. A gene is the storage unit of information that is inherited from parents to offspring and the genome is the set of DNA sequences that characterize a person. One could compare nucleotides with letters, genes with phrases and the genome with an encyclopedia where each volume is a chromosome.

      Epigenetics studies heritable changes that affect gene expression, activation or deactivation of genes,

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