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    Huntington’s Chorea, A Simple Guide To The Condition, Treatment And Related Conditions
    Huntington’s Chorea, A Simple Guide To The Condition, Treatment And Related Conditions
    Huntington’s Chorea, A Simple Guide To The Condition, Treatment And Related Conditions
    Ebook114 pages1 hour

    Huntington’s Chorea, A Simple Guide To The Condition, Treatment And Related Conditions

    By Kenneth Kee

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    About this ebook

    Huntington's Chorea is a progressive degenerative disease affecting basal ganglia characterized by choreiform movements and mental deterioration.
    The cause is believed to be genetic with autosomal dominance transmission from parent to offspring with full penetrance.
    In Huntington's Chorea, there are widespread degeneration changes with cell loss and reactive gliosis mainly in the cerebral cortex, basal ganglia and caudate nucleus.
    There is deficiency of gamma-aminobutyric acid (GABA).
    Physical symptoms of Huntington's disease can begin at any age from infancy to old age but usually begin between 30 and 45 years of age.
    1. Choreiform movements
    2. Emotional disturbance with mental changes
    3. Cognitive impairment
    The diagnosis of Huntington's Chorea involve
    1. Typical history of choreiform movements, emotional and mental impairment with family history.
    2. Physical and neurological examinations for brain neurological deficit.
    3. CT scan or MRI may show selective atrophy of the caudate nucleus helping to differentiate Huntingdon's Chorea from other causes such as dementia.
    There is no cure for Huntington's Chorea but symptomatic control of choreiform movements with haliperidol or chlorpromazine may help.
    Tetrabenazine was approved in 2008 for treatment of chorea in Huntington's disease in the US.
    Other drugs that help to reduce chorea include neuroleptics and benzodiazepines.
    Newer agents, such as quetiapine, clozapine, olanzapine, and risperidone, are preferred to older agents because of the lower incidence of extrapyramidal side effects and the decreased risk for tardive syndromes.
    Results of some studies have suggested that valproic acid and clonazepam may be effective in the treatment of chorea.
    Patients with Huntington's disease may see a physical therapist for non-invasive and non-medication-based ways of managing the physical symptoms.
    TABLE OF CONTENT
    Introduction
    Chapter 1 Huntington’s Chorea
    Chapter 2 More Facts of Huntington’s Chorea
    Chapter 3 Treatment of Huntington’s Chorea
    Chapter 4 Cerebral Palsy
    Chapter 5 Parkinson's Disease
    Chapter 6 Dementia
    Chapter 7 Seizures
    Epilogue

    Ode to Huntington's Chorea

    Huntington's Chorea is a progressive degenerative brain condition
    The affected basal ganglia causes choreiform movements and mental deterioration
    It is adult-onset, autosomal dominant inherited disorder
    Most adult-onset Huntingtons inherit the gene from their mothers

    The juvenile Huntingtons inherit the gene from their fathers
    Inheritance through the father can lead to the disease onset earlier
    The most important symptom is the choreiform movements
    There is usually emotional disturbance and cognitive impairment

    Diagnosis is from the history of chorea and poor mental abilities
    CT scan or MRI may show the caudate nucleus having selective atrophy
    There is no cure for Huntington's Chorea
    Mental impairment may finally lead to dementia

    Treatment is with medications to control the symptoms
    Psychotic drugs are given for psychosis and behavioral problems
    Drugs that help to reduce chorea include Tetrabenazine
    Other drugs that help include neuroleptics and benzodiazepines

    -An original poem by Kenneth Kee

    LanguageEnglish
    PublisherKenneth Kee
    Release dateDec 17, 2016
    ISBN9781370905157
    Huntington’s Chorea, A Simple Guide To The Condition, Treatment And Related Conditions
    Author

    Kenneth Kee

    Medical doctor since 1972.Started Kee Clinic in 1974 at 15 Holland Dr #03-102, relocated to 36 Holland Dr #01-10 in 2009.Did my M.Sc (Health Management ) in 1991 and Ph.D (Healthcare Administration) in 1993.Dr Kenneth Kee is still working as a family doctor at the age of 74However he has reduced his consultation hours to 3 hours in the morning and 2 hours inthe afternoon.He first started writing free blogs on medical disorders seen in the clinic in 2007 on http://kennethkee.blogspot.com.His purpose in writing these simple guides was for the health education of his patients which is also his dissertation for his Ph.D (Healthcare Administration). He then wrote an autobiography account of his journey as a medical student to family doctor on his other blog http://afamilydoctorstale.blogspot.comThis autobiography account “A Family Doctor’s Tale” was combined with his early “A Simple Guide to Medical Disorders” into a new Wordpress Blog “A Family Doctor’s Tale” on http://ken-med.com.From which many free articles from the blog was taken and put together into 1000 eBooks.He apologized for typos and spelling mistakes in his earlier books.He will endeavor to improve the writing in futures.Some people have complained that the simple guides are too simple.For their information they are made simple in order to educate the patients.The later books go into more details of medical disorders.He has published 1000 eBooks on various subjects on health, 1 autobiography of his medical journey, another on the autobiography of a Cancer survivor, 2 children stories and one how to study for his nephew and grand-daughter.The purpose of these simple guides is to educate patient on health disorders and not meant as textbooks.He does not do any night duty since 2000 ever since Dr Tan had his second stroke.His clinic is now relocated to the Buona Vista Community Centre.The 2 units of his original clinic are being demolished to make way for a new Shopping Mall.He is now doing some blogging and internet surfing (bulletin boards since the 1980's) startingwith the Apple computer and going to PC.The entire PC is upgraded by himself from XT to the present Pentium duo core.The present Intel i7 CPU is out of reach at the moment because the CPU is still expensive.He is also into DIY changing his own toilet cistern and other electric appliance.His hunger for knowledge has not abated and he is a lifelong learner.The children have all grown up and there are 2 grandchildren who are even more technically advanced than the grandfather where mobile phones are concerned.This book is taken from some of the many articles in his blog (now with 740 posts) A Family Doctor’s Tale.Dr Kee is the author of:"A Family Doctor's Tale""Life Lessons Learned From The Study And Practice Of Medicine""Case Notes From A Family Doctor"

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      Book preview

      Huntington’s Chorea, A Simple Guide To The Condition, Treatment And Related Conditions - Kenneth Kee

      Huntington’s Chorea,

      A

      Simple

      Guide

      To

      The Condition,

      Treatment

      And

      Related Conditions

      by

      Dr Kenneth Kee

      M.B.,B.S. (Singapore)

      Ph.D (Healthcare Administration)

      Copyright Kenneth Kee 2014 Smashwords Edition

      Published By Kenneth Kee at Smashwords.com

      Dedication

      This book is dedicated

      To my wife Dorothy

      And my children

      Carolyn, Grace

      And Kelvin

      This book describes the Huntington’s Chorea and The Treatments and Related Diseases or in vernacular terms

      (What You Need to treat Huntington’s Chorea)

      This eBook is licensed for the personal enjoyment only. This eBook may not be re-sold or given away to other people. If you would like to share this book with another person, please purchase an additional copy for each reader.

      If you’re reading this book and did not purchase it, or it was not purchased for your use only, then please return to Smashwords.com and purchase your own copy.

      Thank you for respecting the hard work of this author.

      Introduction

      Ode to Huntington's Chorea

      Huntington's Chorea is a progressive degenerative brain condition

      The affected basal ganglia causes choreiform movements and mental deterioration

      It is adult-onset, autosomal dominant inherited disorder

      Most adult-onset Huntingtons inherit the gene from their mothers

      The juvenile Huntingtons inherit the gene from their fathers

      Inheritance through the father can lead to the disease onset earlier

      The most important symptom is the choreiform movements

      There is usually emotional disturbance and cognitive impairment

      Diagnosis is from the history of chorea and poor mental abilities

      CT scan or MRI may show the caudate nucleus having selective atrophy

      There is no cure for Huntington's Chorea

      Mental impairment may finally lead to dementia

      Treatment is with medications to control the symptoms

      Psychotic drugs are given for psychosis and behavioral problems

      Drugs that help to reduce chorea include Tetrabenazine

      Other drugs that help include neuroleptics and benzodiazepines

      -An original poem by Kenneth Kee

      Interesting Tips about the Huntington's Chorea

      A Healthy Lifestyle

      1. Take a well Balanced Diet

      2. There is no cure for Huntington's Chorea but symptomatic control of choreiform movements with haliperidol or chlorpromazine may help.

      Tetrabenazine was approved in 2008 for treatment of chorea in Huntington's disease in the US.

      Other drugs that help to reduce chorea include neuroleptics and benzodiazepines.

      Compounds such as amantadine or remacemide are still under investigation but have shown preliminary positive results.

      Hypokinesia and rigidity, especially in juvenile cases, can be treated with anti-parkinsonian drugs, and myoclonic hyperkinesia can be treated with valproic acid.

      Psychiatric symptoms can be treated with medications similar to those used in the general population.

      Selective serotonin reuptake inhibitors and mirtazapine have been recommended for depression, while atypical antipsychotic drugs are recommended for psychosis and behavioral problems.

      Weight loss and eating difficulties due to dysphagia and other muscle discoordination are common, making nutrition management increasingly important as the disease advances.

      As the condition progress hospitalization or institutional care is usually indicated.

      Genetic counseling is important for treatment and prevention of Huntington's Chorea.

      3. Keep bones and body strong

      Bone marrow produces our blood

      Eat foods rich in calcium like yogurt, cheese, milk, and dark green vegetables.

      Eat foods rich in Vitamin D, like eggs, fatty fish, cereal, and fortified milk.

      Eat food rich in Vitamins B and C such as green vegetables and fruits

      Zinc and other minerals are important to the body

      4. Get enough rest and Sleep

      Avoid stress and tension

      5. Exercise and stay active.

      It is best to do weight-bearing exercise such as walking, jogging, stair climbing, dancing, or lifting weights for 2½ hours a week.

      One way to do this is to be active 30 minutes a day at least 5 days a week.

      Begin slowly especially if a person has not been active.

      6. Do not drink more than 2 alcohol drinks a day for a man or 1 alcohol drink a day for a woman.

      Alcohol use also increases the chance of falling and breaking a bone.

      Alcohol can affect the neurons and brain cells.

      7. Stop or do not begin smoking.

      It also interferes with blood supply and healing.

      Chapter 1

      Huntingdon’s Chorea

      What is Huntington's Chorea?

      Huntington's Chorea is a progressive degenerative disease affecting basal ganglia characterized by choreiform movements and mental deterioration.

      What causes Huntington's Chorea?

      The cause is believed to be genetic with autosomal dominance transmission from parent to offspring with full penetrance.

      In Huntington's Chorea, there are widespread degeneration changes with cell loss and reactive gliosis mainly in the cerebral cortex, basal ganglia and caudate nucleus.

      The disease is caused by an autosomal dominant mutation in either of an individual's two copies of a gene called huntingtin which means any child of an affected person typically has a 50% chance of inheriting the disease.

      There is deficiency of gamma-aminobutyric acid (GABA).

      Who is at risk of Huntington's Chorea?

      Huntington's Chorea affects sexes in equal numbers.

      On average 50 per cent of children of the sufferers

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