Everand Logo

Welcome to Everand!

  • Discover millions of ebooks, audiobooks, and so much more with a free trial

    Only $11.99/month after trial. Cancel anytime.

    Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs
    Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs
    Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs
    Ebook317 pages13 hours

    Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs

    ()

    Read preview

    About this ebook

    There is now enough basic work to sketch out the principal systems at all levels of the brain, from prefrontal cortex to lower brainstem, which are orchestrated to provide control of food selection, preference and consumption. At the same time, the complex interplay between central systems and signals generated from peripheral systems include the gut, liver and fat stores, as well as the interactions with the neuroendocrine system can be described in some detail. A continuing theme throughout the book is that the functional analysis of appetite and food intake cannot be limited to a single focus, e.g. hypothalamic neuropeptides and their interactions, but must be based on a fully integrated view of the several contributing systems.

    Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs provides an expert guide to the neural, neurochemical, autonomic and endocrine interrelations which underpin appetite and the controls of food intake and body weight. The book covers many of the neurochemical entities that are currently under investigation, including: neuropeptides, leptin, insulin, monoamines and endogenous cannabinoids in relation to appetite and body-weight control. In addition to the neuroscience analysis, there are also chapters that provide an expert guide to some of the key psychological concepts that the researchers believe are essential in trying to understand the phenomena under investigation. The volume will also serve as an authoritative guide to the current emphasis on the development of novel, efficacious anti-obesity medication.

    • Provides an integrative view of the many systems involved in appetite how they interact to effect food intake (i.e. the brain, endocrine, gut, liver etc.)
    • Considers psychological aspects such as incentive, preference, liking and palatability, and sets these concepts in their behavioural, pharmacological and neural contexts
    • Examines the development of novel anti-obesity drugs, drawing on experience of pharmacological development work, pre-clinical tests for anti-obesity efficacy, and clinical trials of candidate anti-obesity compounds
    LanguageEnglish
    PublisherAcademic Press
    Release dateApr 28, 2011
    ISBN9780080466460
    Appetite and Body Weight: Integrative Systems and the Development of Anti-Obesity Drugs

    Related to Appetite and Body Weight

    Related ebooks

    Medical For You

    View More
    View More

    Related podcast episodes

    Related articles

    • Article

      Gut Feeling

      Nov 4, 2023

      Gut Feeling
      5 min read

    • Article

      For Diabetics, A High-fiber Diet Feeds Gut Microbes, Lowering Blood Sugar

      Mar 8, 2018

      A high-fiber diet plus some good microbes can keep diabetics' blood sugar in check, a new study finds.

      2 min read

    • Article

      The Gut-brain Axis

      Jul 24, 2022

      Cynthia Thurlow likes to remind her patients that digestion begins in the brain, in the way people think about their food before they have even taken a bite. Conversely, 95 percent of the mood-regulating neurotransmitter serotonin, which is targeted

      1 min read

    • Article

      References

      Mar 5, 2023

      HOW BETTER SLEEP CAN HELP WITH A HEALTHY WEIGHT, p28 Health Navigator. Common Sleep Problems. Available at www. healthnavigator.org.nz Accessed February 2023. Katsunuma et.al. 2017. Unrecognized Sleep Loss Accumulated in Daily Life Can Promote Brain

      2 min read

    • Article

      Gene Variants May Make Obesity ‘All But Inevitable’

      Nov 15, 2017

      New evidence shows that at least some of the weight gain that plagues modern humans is predetermined. Variants in a gene called ankyrin-B—which millions of Americans carry—could cause people to put on pounds, according to a new study with mice. “In c

      3 min read

    • Article

      Go With your Gut

      Dec 2, 2021

      Go With your Gut
      6 min read

    • Article

      Our Food Is Killing Us

      Dec 10, 2021

      Our Food Is Killing Us
      16 min read

    • Article

      Top health

      Sep 29, 2023

      Top health
      3 min read

    • Article

      Our Food Is Killing Us

      Dec 10, 2021

      Our Food Is Killing Us
      16 min read

    • Article

      The Metabolic Approach

      Nov 21, 2021

      Almost 100 years ago, the German physician, researcher and Nobel Laureate Otto Warburg proposed that the primary cause of cancer is a metabolic dysfunction of the mitochondria. Mitochondria are the cellular powerplants that produce ATP, the energy so

      2 min read

    • Article

      How To Have A HEALTHY GUT

      Feb 19, 2023

      How To Have A HEALTHY GUT
      5 min read

    • Article

      How To Have A HEALTHY GUT

      Feb 19, 2023

      How To Have A HEALTHY GUT
      5 min read

    • Article

      You Are What You Just Ate

      Mar 10, 2023

      You Are What You Just Ate
      15 min read

    • Article

      You Are What You Just Ate

      Mar 10, 2023

      You Are What You Just Ate
      15 min read

    • Article

      Holistic Helpers For Bipolar Disorder

      Nov 21, 2021

      Q My daughter has bipolar disorder and takes medication for it, but still suffers badly with symptoms. Can you recommend any holistic therapies? S.K., via email A Formerly known as manic depression, bipolar disorder affects more than 1 percent of

      4 min read

    • Article

      Gut Reaction

      Apr 19, 2023

      Gut Reaction
      9 min read

    • Article

      References

      Mar 4, 2024

      Jianqin et al. 2015. Effects of milk containing only A2 beta casein versus milk containing both A1 and A2 beta casein proteins on gastrointestinal physiology, symptoms of discomfort, and cognitive behavior of people with self-reported intolerance to

      2 min read

    • Article

      The Ultimate Guide To Your

      Nov 16, 2021

      The Ultimate Guide To Your
      7 min read

    • Article

      Gut Instincts

      Jun 14, 2019

      Gut Instincts
      3 min read

    Related categories

    Reviews for Appetite and Body Weight

    0 ratings

    0 ratings0 reviews

    What did you think?

    Tap to rate

    Review must be at least 10 words

      Book preview

      Appetite and Body Weight - Tim Kirkham

      Enjoying the preview?
      Page 1 of 1